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7ZC4
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BU of 7zc4 by Molmil
Cryo-EM structure of POLRMT mutant.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2022-03-25
Release date:2023-02-01
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7O9M
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BU of 7o9m by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2021-04-16
Release date:2021-06-30
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
7O9K
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BU of 7o9k by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2021-04-16
Release date:2021-06-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
7PZP
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BU of 7pzp by Molmil
Mitochondrial DNA dependent RNA polymerase homodimer.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-09-28
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
2UW2
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BU of 2uw2 by Molmil
Crystal structure of human ribonucleotide reductase subunit R2
Descriptor: FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT
Authors:Welin, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Stenmark, P, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
9ENP
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BU of 9enp by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch
Descriptor: CALCIUM ION, DNA (46-MER), DNA (67-MER), ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2024-03-13
Release date:2024-05-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.12 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM.
Nucleic Acids Res., 52, 2024
9ENQ
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BU of 9enq by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch
Descriptor: CALCIUM ION, DNA (46-MER), DNA (67-MER), ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2024-03-13
Release date:2024-05-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.12 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM.
Nucleic Acids Res., 52, 2024
8C2R
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BU of 8c2r by Molmil
SARS-CoV2 Omicron BA.1 spike in complex with CAB-A17 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CAB-A17 antibody (HC), ...
Authors:Das, H, Hallberg, B.M.
Deposit date:2022-12-22
Release date:2024-05-22
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:SARS-CoV-2 omicron Spike (RBD) in complex with CAB-A17 antibody
To Be Published
8C0Y
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BU of 8c0y by Molmil
SARS-CoV2 Omicron BA.1 RBD in complex with CAB-A17 antibody
Descriptor: CAB-A17 antibody (variable), Spike protein S2'
Authors:Das, H, Hallberg, B.M.
Deposit date:2022-12-19
Release date:2024-06-19
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies.
Cell Rep Med, 5, 2024
7PZR
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BU of 7pzr by Molmil
Cryo-EM structure of POLRMT in free form.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-11-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
4XGM
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BU of 4xgm by Molmil
Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.98A
Descriptor: GLYCEROL, Mitochondrial ribonuclease P protein 3, ZINC ION
Authors:Reinhard, L, Sridhara, S, Hallberg, B.M.
Deposit date:2014-12-31
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the nuclease subunit of human mitochondrial RNase P.
Nucleic Acids Res., 43, 2015
4XGL
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BU of 4xgl by Molmil
Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A
Descriptor: GLYCEROL, Mitochondrial ribonuclease P protein 3, ZINC ION
Authors:Reinhard, L, Sridhara, S, Hallberg, B.M.
Deposit date:2014-12-31
Release date:2015-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the nuclease subunit of human mitochondrial RNase P.
Nucleic Acids Res., 43, 2015
8UMC
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BU of 8umc by Molmil
Deinococcus aerius TR0125 C-glucosyl deglycosidase (CGD), cryo-EM
Descriptor: DUF6379 domain-containing protein, MANGANESE (II) ION, Xylose isomerase-like TIM barrel domain-containing protein
Authors:Furlanetto, V, Kalyani, D.C, Kostelac, A, Haltrich, D, Hallberg, B.M, Divne, C.
Deposit date:2023-10-17
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural and Functional Characterization of a Gene Cluster Responsible for Deglycosylation of C-glucosyl Flavonoids and Xanthonoids by Deinococcus aerius.
J.Mol.Biol., 436, 2024
5A2W
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BU of 5a2w by Molmil
Crystal structure of mtPAP in complex with ATPgammaS
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MITOCHONDRIAL PROTEIN, ...
Authors:Lapkouski, M, Hallberg, B.M.
Deposit date:2015-05-26
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
8AS5
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BU of 8as5 by Molmil
CryoEM structure of the human Nucleophosmin 1 core
Descriptor: Nucleophosmin
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2022-08-18
Release date:2023-02-15
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1.
Pnas Nexus, 2, 2023
3BHD
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BU of 3bhd by Molmil
Crystal structure of human thiamine triphosphatase (THTPA)
Descriptor: CHLORIDE ION, CITRIC ACID, GLYCEROL, ...
Authors:Busam, R.D, Lehtio, L, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC)
Deposit date:2007-11-28
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Human Thiamine Triphosphatase.
To be Published
3BIN
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BU of 3bin by Molmil
Structure of the DAL-1 and TSLC1 (372-383) complex
Descriptor: Band 4.1-like protein 3, Cell adhesion molecule 1
Authors:Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Persson, C, Hallberg, B.M.
Deposit date:2007-11-30
Release date:2008-01-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B)
J.Biol.Chem., 286, 2011
3B7K
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BU of 3b7k by Molmil
Human Acyl-coenzyme A thioesterase 12
Descriptor: Acyl-coenzyme A thioesterase 12, COENZYME A
Authors:Lehtio, L, Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human Acyl-coenzyme A thioesterase 12.
To be Published
3C5N
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BU of 3c5n by Molmil
Structure of human TULP1 in complex with IP3
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Tubby-related protein 1
Authors:Busam, R.D, Lehtio, L, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC)
Deposit date:2008-01-31
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human TULP1 in complex with IP3
To be published
3M66
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BU of 3m66 by Molmil
Crystal structure of human Mitochondrial Transcription Termination Factor 3
Descriptor: mTERF domain-containing protein 1, mitochondrial
Authors:Spahr, H, Samuelsson, T, Hallberg, B.M, Gustafsson, C.M.
Deposit date:2010-03-15
Release date:2010-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain.
Biochem.Biophys.Res.Commun., 397, 2010
2C4K
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BU of 2c4k by Molmil
Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)
Descriptor: PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Kursula, P, Stenmark, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
Deposit date:2005-10-20
Release date:2005-10-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39)
To be Published
2BON
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BU of 2bon by Molmil
Structure of an Escherichia coli lipid kinase (YegS)
Descriptor: LIPID KINASE, MAGNESIUM ION
Authors:Bakali, H.M, Johnson, K.A, Hallberg, B.M, Herman, M.D, Nordlund, P.
Deposit date:2005-04-12
Release date:2006-10-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Yegs, a Homologue to the Mammalian Diacylglycerol Kinases, Reveals a Novel Regulatory Metal Binding Site.
J.Biol.Chem., 282, 2007
7NS6
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BU of 7ns6 by Molmil
SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ...
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-03-05
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
5A2Y
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BU of 5a2y by Molmil
Crystal structure of mtPAP in complex with UTP
Descriptor: MAGNESIUM ION, MITOCHONDRIAL PROTEIN, URIDINE 5'-TRIPHOSPHATE
Authors:Lapkouski, M, Hallberg, B.M.
Deposit date:2015-05-26
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015
5A30
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BU of 5a30 by Molmil
Crystal structure of mtPAP N472D mutant in complex with ATPgammaS
Descriptor: MAGNESIUM ION, MITOCHONDRIAL PROTEIN, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Lapkouski, M, Hallberg, B.M.
Deposit date:2015-05-26
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Nucleic Acids Res., 43, 2015

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