8XJ6
| The Cryo-EM structure of MPXV E5 apo conformation | Descriptor: | AMP PHOSPHORAMIDATE, Monkeypox virus E5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhang, W, Liu, Y, Gao, H, Gan, J. | Deposit date: | 2023-12-20 | Release date: | 2024-05-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structural and functional insights into the helicase protein E5 of Mpox virus. Cell Discov, 10, 2024
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8XJ7
| The Cryo-EM structure of MPXV E5 in complex with DNA | Descriptor: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | Authors: | Zhang, W, Liu, Y, Gao, H, Gan, J. | Deposit date: | 2023-12-20 | Release date: | 2024-05-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural and functional insights into the helicase protein E5 of Mpox virus. Cell Discov, 10, 2024
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7L4S
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5A8H
| cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5, ... | Authors: | Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P. | Deposit date: | 2015-07-15 | Release date: | 2015-08-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env. Cell, 162, 2015
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5A7X
| negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195, ... | Authors: | Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P. | Deposit date: | 2015-07-10 | Release date: | 2015-08-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env. Cell(Cambridge,Mass.), 162, 2015
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2FVO
| Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1 | Descriptor: | Peptide chain release factor 1 | Authors: | Rawat, U, Gao, H, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | Deposit date: | 2006-01-31 | Release date: | 2006-04-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12.8 Å) | Cite: | Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM. J.Mol.Biol., 357, 2006
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2GOY
| Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS | Descriptor: | ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, adenosine phosphosulfate reductase | Authors: | Chartron, J, Carroll, K.S, Shiau, C, Gao, H, Leary, J.A, Bertozzi, C.R, Stout, C.D. | Deposit date: | 2006-04-14 | Release date: | 2006-09-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase. J.Mol.Biol., 364, 2006
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8K5R
| CDK9/cyclin T1 in complex with KB-0742 | Descriptor: | (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 | Authors: | Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.751 Å) | Cite: | Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. J.Med.Chem., 66, 2023
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3TL8
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7YEH
| Cryo-EM structure of human OGT-OGA complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | Authors: | Lu, P, Liu, Y, Yu, H, Gao, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
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7YLL
| Crystal structure of TTEDbh | Descriptor: | DNA polymerase IV, MAGNESIUM ION, PHOSPHATE ION | Authors: | Yan, X, Tian, L, Gao, H. | Deposit date: | 2022-07-26 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.6000092 Å) | Cite: | Structure and function of extreme TLS DNA polymerase TTEDbh from Thermoanaerobacter tengcongensis. Int.J.Biol.Macromol., 253, 2023
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6M4J
| SspA in complex with cysteine | Descriptor: | CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein | Authors: | Liu, L, Gao, H. | Deposit date: | 2020-03-07 | Release date: | 2020-04-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. Mbio, 11, 2020
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7XYF
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7XYG
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7XXE
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6USN
| Co-crystal structure of SPR with compound 5 | Descriptor: | (2-hydroxyphenyl)[3-methyl-1-(pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Huang, X, Wang, K. | Deposit date: | 2019-10-28 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.773 Å) | Cite: | Virtual screening to identify potent sepiapterin reductase inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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2H5E
| Crystal structure of E.coli polypeptide release factor RF3 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor RF-3 | Authors: | Song, H.W, Zhou, Z.H. | Deposit date: | 2006-05-26 | Release date: | 2007-05-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors Cell(Cambridge,Mass.), 129, 2007
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5HVU
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7E6R
| Crystal structure of HCoV-NL63 3C-like protease,pH5.6 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | Deposit date: | 2021-02-23 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6L
| Crystal structure of HCoV-NL63 3C-like protease,pH5.0 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78037143 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6M
| Crystal structure of Human coronavirus NL63 3C-like protease | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.83445024 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6N
| Crystal structure of HCoV-NL63 3C-like protease,pH5.2 | Descriptor: | 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-02-22 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8413 Å) | Cite: | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7DRI
| Structure of SspE_CTD_41658 | Descriptor: | DUF1524 domain | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-28 | Release date: | 2022-06-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRS
| Structure of SspE_40224 | Descriptor: | SspE protein | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-29 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRR
| Structure of SspE-R100A protein | Descriptor: | SspE protein | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-29 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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