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PDB: 1 results

Rho-associated protein kinase 1 (ROCK 1) in complex with a pyridine thiazole piperidine inhibitor
Descriptor:	2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamide, Rho-associated protein kinase 1
Authors:	Jacobs, M.J.
Deposit date:	2016-01-28
Release date:	2017-02-08
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	ROCK inhibitors 2. Improving potency, selectivity and solubility through the application of rationally designed solubilizing groups. Bioorg. Med. Chem. Lett., 2018