4J0N
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![BU of 4j0n by Molmil](/molmil-images/mine/4j0n) | Crystal structure of a manganese dependent isatin hydrolase | Descriptor: | CALCIUM ION, Isatin hydrolase B, MANGANESE (II) ION, ... | Authors: | Bjerregaard-Andersen, K, Sommer, T, Jensen, J.K, Jochimsen, B, Etzerodt, M, Morth, J.P. | Deposit date: | 2013-01-31 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A proton wire and water channel revealed in the crystal structure of isatin hydrolase. J.Biol.Chem., 289, 2014
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4M8D
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![BU of 4m8d by Molmil](/molmil-images/mine/4m8d) | Crystal structure of an isatin hydrolase bound to product analogue thioisatinate | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Putative uncharacterized protein, ... | Authors: | Bjerregaard-Andersen, K, Sommer, T, Jensen, J.K, Jochimsen, B, Etzerodt, M, Morth, J.P. | Deposit date: | 2013-08-13 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A proton wire and water channel revealed in the crystal structure of isatin hydrolase. J.Biol.Chem., 289, 2014
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2VKZ
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![BU of 2vkz by Molmil](/molmil-images/mine/2vkz) | Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FATTY ACID SYNTHASE SUBUNIT ALPHA, ... | Authors: | Johansson, P, Wiltschi, B, Kumari, P, Kessler, B, Vonrhein, C, Vonck, J, Oesterhelt, D, Grininger, M. | Deposit date: | 2008-01-07 | Release date: | 2008-08-12 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex. Proc.Natl.Acad.Sci.USA, 105, 2008
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2W3L
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![BU of 2w3l by Molmil](/molmil-images/mine/2w3l) | Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex | Descriptor: | 1-(2-{[(3S)-3-(aminomethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-4-chloro-5-methyl-N,N-diphenyl-1H-pyrazole-3-carboxamide, APOPTOSIS REGULATOR BCL-2 | Authors: | Porter, J, Payne, A, de Candole, B, Ford, D, Hutchinson, B, Trevitt, G, Turner, J, Edwards, C, Watkins, C, Whitcombe, I, Davis, J, Stubberfield, C, Fisher, M, Lamers, M. | Deposit date: | 2008-11-13 | Release date: | 2008-12-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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2QOS
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![BU of 2qos by Molmil](/molmil-images/mine/2qos) | Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8 | Descriptor: | Complement component 8, gamma polypeptide, Complement component C8 alpha chain | Authors: | Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L. | Deposit date: | 2007-07-20 | Release date: | 2007-10-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding. Mol.Immunol., 45, 2008
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2Q6P
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![BU of 2q6p by Molmil](/molmil-images/mine/2q6p) | The Chemical Control of Protein Folding: Engineering a Superfolder Green Fluorescent Protein | Descriptor: | Green fluorescent protein mutant 3 | Authors: | Steiner, T, Hess, P, Bae, J.H, Wiltschi, B, Moroder, L, Budisa, N. | Deposit date: | 2007-06-05 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline. Plos One, 3, 2008
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1H8N
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![BU of 1h8n by Molmil](/molmil-images/mine/1h8n) | Three-dimensional structure of anti-ampicillin single chain Fv fragment from phage-displayed murine antibody libraries | Descriptor: | GLYCEROL, MUTANT AL2 6E7S9G, SULFATE ION | Authors: | Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-14 | Release date: | 2001-08-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The Importance of Framework Residues H6, H7 and H10 in Antibody Heavy Chains: Experimental Evidence for a New Structural Subclassification of Antibody V(H) Domains J.Mol.Biol., 309, 2001
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1H8O
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![BU of 1h8o by Molmil](/molmil-images/mine/1h8o) | Three-dimensional structure of anti-ampicillin single chain Fv fragment. | Descriptor: | MUTANT AL2 6E7P9G, SULFATE ION | Authors: | Burmester, J, Spinelli, S, Pugliese, L, Krebber, A, Honegger, A, Jung, S, Schimmele, B, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-14 | Release date: | 2001-08-02 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Selection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries J.Mol.Biol., 309, 2001
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2YFY
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![BU of 2yfy by Molmil](/molmil-images/mine/2yfy) | SERCA in the HnE2 State Complexed With Debutanoyl Thapsigargin | Descriptor: | DEBUTANOYL THAPSIGARGIN, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Sonntag, Y, Musgaard, M, Olesen, C, Schiott, B, Moller, J.V, Nissen, P, Thogersen, L. | Deposit date: | 2011-04-11 | Release date: | 2011-06-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mutual Adaptation of a Membrane Protein and its Lipid Bilayer During Conformational Changes. Nat.Commun., 2, 2011
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2WLB
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![BU of 2wlb by Molmil](/molmil-images/mine/2wlb) | Adrenodoxin-like ferredoxin Etp1fd(516-618) of Schizosaccharomyces pombe mitochondria | Descriptor: | ELECTRON TRANSFER PROTEIN 1, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER | Authors: | Mueller, J.J, Hannemann, F, Schiffler, B, Bernhardt, R, Heinemann, U. | Deposit date: | 2009-06-23 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Thermodynamic Characterization of the Adrenodoxin-Like Domain of the Electron-Transfer Protein Etp1 from Schizosaccharomyces Pombe. J.Inorg.Biochem., 105, 2011
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1H8S
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![BU of 1h8s by Molmil](/molmil-images/mine/1h8s) | Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten. | Descriptor: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, MUTANT AL2 6E7P9G, SULFATE ION | Authors: | Burmester, J, Spinelli, S, Pugliese, L, Krebber, A, Honegger, A, Jung, S, Schimmele, B, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-15 | Release date: | 2001-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Selection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries J.Mol.Biol., 309, 2001
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1I3G
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![BU of 1i3g by Molmil](/molmil-images/mine/1i3g) | CRYSTAL STRUCTURE OF AN AMPICILLIN SINGLE CHAIN FV, FORM 1, FREE | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ANTIBODY FV FRAGMENT | Authors: | Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-15 | Release date: | 2001-10-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries. J.Mol.Biol., 309, 2001
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6GHW
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![BU of 6ghw by Molmil](/molmil-images/mine/6ghw) | Substituting the prolines of 4-oxalocrotonate tautomerase with non-canonical analogue (2S)-3,4-dehydroproline | Descriptor: | 2-hydroxymuconate tautomerase, CALCIUM ION | Authors: | Pavkov-Keller, T, Lukesch, M.S, Wiltschi, B, Gruber, K. | Deposit date: | 2018-05-09 | Release date: | 2019-03-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substituting the catalytic proline of 4-oxalocrotonate tautomerase with non-canonical analogues reveals a finely tuned catalytic system. Sci Rep, 9, 2019
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5JAE
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![BU of 5jae by Molmil](/molmil-images/mine/5jae) | LeuT in the outward-oriented, Na+-free return state, P21 form at pH 6.5 | Descriptor: | Transporter, octyl beta-D-glucopyranoside | Authors: | Malinauskaite, L, Sahin, C, Said, S, Grouleff, J, Shahsavar, A, Bjerregaard, H, Noer, P, Severinsen, K, Boesen, T, Schiott, B, Sinning, S, Nissen, P. | Deposit date: | 2016-04-12 | Release date: | 2016-06-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state. Nat Commun, 7, 2016
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5JAG
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![BU of 5jag by Molmil](/molmil-images/mine/5jag) | LeuT T354H mutant in the outward-oriented, Na+-free Return State | Descriptor: | Transporter, octyl beta-D-glucopyranoside | Authors: | Malinauskaite, L, Sahin, C, Said, S, Grouleff, J, Shahsavar, A, Bjerregaard, H, Noer, P, Severinsen, K, Boesen, T, Schiott, B, Sinning, S, Nissen, P. | Deposit date: | 2016-04-12 | Release date: | 2016-06-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state. Nat Commun, 7, 2016
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5JAF
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![BU of 5jaf by Molmil](/molmil-images/mine/5jaf) | LeuT Na+-free Return State, C2 form at pH 5 | Descriptor: | Transporter, octyl beta-D-glucopyranoside | Authors: | Malinauskaite, L, Sahin, C, Said, S, Grouleff, J, Shahsavar, A, Bjerregaard, H, Noer, P, Severinsen, K, Boesen, T, Schiott, B, Sinning, S, Nissen, P. | Deposit date: | 2016-04-12 | Release date: | 2016-06-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.021 Å) | Cite: | A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state. Nat Commun, 7, 2016
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7L23
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![BU of 7l23 by Molmil](/molmil-images/mine/7l23) | |
6IEH
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![BU of 6ieh by Molmil](/molmil-images/mine/6ieh) | Crystal structures of the hMTR4-NRDE2 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | Authors: | Chen, J.Y, Yun, C.H. | Deposit date: | 2018-09-14 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.892 Å) | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. Genes Dev., 33, 2019
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7NSU
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![BU of 7nsu by Molmil](/molmil-images/mine/7nsu) | ColicinE9 intact translocation complex | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ... | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | Deposit date: | 2021-03-08 | Release date: | 2021-08-11 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF. Embo J., 40, 2021
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7NST
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![BU of 7nst by Molmil](/molmil-images/mine/7nst) | ColicinE9 partial translocation complex | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | Deposit date: | 2021-03-08 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF. Embo J., 40, 2021
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3R3K
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![BU of 3r3k by Molmil](/molmil-images/mine/3r3k) | Crystal structure of a parallel 6-helix coiled coil | Descriptor: | 1,2-ETHANEDIOL, CChex-Phi22 helix, CHLORIDE ION, ... | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | Deposit date: | 2011-03-16 | Release date: | 2011-11-16 | Last modified: | 2011-11-30 | Method: | X-RAY DIFFRACTION (2.2009 Å) | Cite: | A de novo peptide hexamer with a mutable channel. Nat.Chem.Biol., 7, 2011
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3R46
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![BU of 3r46 by Molmil](/molmil-images/mine/3r46) | Crystal structure of a parallel 6-helix coiled coil CC-hex-D24 | Descriptor: | CHLORIDE ION, GLYCEROL, SODIUM ION, ... | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | Deposit date: | 2011-03-17 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | A de novo peptide hexamer with a mutable channel. Nat.Chem.Biol., 7, 2011
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3R4A
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![BU of 3r4a by Molmil](/molmil-images/mine/3r4a) | |
3R48
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![BU of 3r48 by Molmil](/molmil-images/mine/3r48) | Crystal structure of a hetero-hexamer coiled coil | Descriptor: | GLYCEROL, coiled coil helix W22-L24H, coiled coil helix Y15-L24D | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | Deposit date: | 2011-03-17 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0011 Å) | Cite: | A de novo peptide hexamer with a mutable channel. Nat.Chem.Biol., 7, 2011
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3R4H
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![BU of 3r4h by Molmil](/molmil-images/mine/3r4h) | |