7L23

HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid

Summary for 7L23

• Entry DOI: 10.2210/pdb7l23/pdb
• Related: 6WC8
• Descriptor: Integrase, SULFATE ION, IODIDE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, hiv integrase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 1
• Total formula weight: 17484.58

Authors

Gorman, M.A.,Parker, M.W. (deposition date: 2020-12-16, release date: 2021-12-22, Last modification date: 2023-10-18)

• Primary citation: Chiew, B.,Scanlon, M.J.; Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.26 Å)