7L23
HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrase | polymer | 150 | 16323.6 | 1 | UniProt (Q76353) Pfam (PF00665) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D, E, F, G, H (A) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 4 | I (A) | 3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzoic acid | non-polymer | 334.3 | 1 | Chemie (XFS) | |||
| 5 | J (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 57 - 206 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Glu 131 | Trp 131 | conflict |
| Ser 154 | Met 154 | conflict |
| Lys 185 | Phe 185 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16323.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1161.0 | |
| All* | Total formula weight | 17484.6 |
