215D
 
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277D
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2AFS
 | | Crystal structure of the genetic mutant R54W of human glutaminyl cyclase | | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2005-07-26 | | Release date: | 2005-08-23 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFZ
 | | Crystal structure of human glutaminyl cyclase in complex with 1-vinylimidazole | | Descriptor: | 1-VINYLIMIDAZOLE, Glutaminyl-peptide cyclotransferase, SULFATE ION, ... | | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2005-07-26 | | Release date: | 2005-08-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AFU
 | | Crystal structure of human glutaminyl cyclase in complex with glutamine t-butyl ester | | Descriptor: | Glutaminyl-peptide cyclotransferase, TERT-BUTYL D-ALPHA-GLUTAMINATE, ZINC ION | | Authors: | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2005-07-26 | | Release date: | 2005-08-23 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2DF7
 | | Crystal structure of infectious bursal disease virus VP2 subviral particle | | Descriptor: | CALCIUM ION, CHLORIDE ION, structural polyprotein VP2 | | Authors: | Ko, T.P, Lee, C.C, Wang, M.Y, Wang, A.H. | | Deposit date: | 2006-02-27 | | Release date: | 2006-06-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity.
J.Struct.Biol., 155, 2006
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1M7J
 | | Crystal structure of D-aminoacylase defines a novel subset of amidohydrolases | | Descriptor: | ACETATE ION, D-aminoacylase, ZINC ION | | Authors: | Liaw, S.-H, Chen, S.-J, Ko, T.-P, Hsu, C.-S, Wang, A.H.-J, Tsai, Y.-C. | | Deposit date: | 2002-07-22 | | Release date: | 2003-02-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of D-Aminoacylase from Alcaligenes faecalis DA1. A NOVEL SUBSET OF AMIDOHYDROLASES AND INSIGHTS INTO THE ENZYME MECHANISM.
J.Biol.Chem., 278, 2003
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3LGZ
 | | Crystal structure of dehydrosqualene synthase Y129A from S. aureus complexed with presqualene pyrophosphate | | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | Authors: | Lin, F.-Y, Liu, Y.-L, Liu, C.-I, Wang, A.H.J, Oldfield, E. | | Deposit date: | 2010-01-21 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1I3W
 | | ACTINOMYCIN D BINDING TO CGATCGATCG | | Descriptor: | 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D | | Authors: | Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | | Deposit date: | 2001-02-17 | | Release date: | 2001-05-21 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg.
Biochemistry, 40, 2001
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1AU6
 | | SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX, DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3') | | Authors: | Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Farrell, N, Wang, A.H.-J. | | Deposit date: | 1997-09-11 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA.
Nat.Struct.Biol., 2, 1995
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1VTE
 | | MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4 | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3') | | Authors: | Aymani, J, Coll, M, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | | Deposit date: | 1990-05-21 | | Release date: | 2011-07-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular structure of nicked DNA: a substrate for DNA repair enzymes.
Proc. Natl. Acad. Sci. U.S.A., 87, 1990
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1AU5
 | | SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | Cisplatin, DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3') | | Authors: | Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Wang, A.H.-J. | | Deposit date: | 1997-09-11 | | Release date: | 1998-02-25 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
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1CA5
 | | INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA | | Descriptor: | 5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3', CHROMOSOMAL PROTEIN SAC7D | | Authors: | Su, S, Gao, Y.-G, Robinson, H, Shriver, J.W, Wang, A.H.-J. | | Deposit date: | 1999-02-23 | | Release date: | 2000-02-23 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs
J.Mol.Biol., 303, 2000
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1CA6
 | | INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA | | Descriptor: | 5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3', CHROMOSOMAL PROTEIN SAC7D | | Authors: | Su, S, Gao, Y.-G, Robinson, H, Shriver, J.W, Wang, A.H.-J. | | Deposit date: | 1999-02-23 | | Release date: | 2000-02-23 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs
J.Mol.Biol., 303, 2000
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1NDN
 | | MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4 | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3') | | Authors: | Aymani, J, Coll, M, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | | Deposit date: | 1992-01-15 | | Release date: | 1992-07-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular structure of nicked DNA: a substrate for DNA repair enzymes.
Proc.Natl.Acad.Sci.USA, 87, 1990
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1UCS
 | | Type III Antifreeze Protein RD1 from an Antarctic Eel Pout | | Descriptor: | Antifreeze peptide RD1 | | Authors: | Ko, T.-P, Robinson, H, Gao, Y.-G, Cheng, C.-H.C, DeVries, A.L, Wang, A.H.-J. | | Deposit date: | 2003-04-21 | | Release date: | 2003-05-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (0.62 Å) | | Cite: | The refined crystal structure of an eel pout type III antifreeze protein RD1 at 0.62-A resolution reveals structural microheterogeneity of protein and solvation.
Biophys.J., 84, 2003
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1V4L
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8KB6
 | | Crystal Structure of Canine TNF-alpha | | Descriptor: | Tumor necrosis factor | | Authors: | Lee, C.C, Wang, A.H.-J. | | Deposit date: | 2023-08-03 | | Release date: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.850166 Å) | | Cite: | Structure-based development of a canine TNF-alpha-specific antibody using adalimumab as a template.
Protein Sci., 33, 2024
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1JP3
 | | Structure of E.coli undecaprenyl pyrophosphate synthase | | Descriptor: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, undecaprenyl pyrophosphate synthase | | Authors: | Ko, T.P, Chen, Y.K, Robinson, H, Tsai, P.C, Gao, Y.G, Chen, A.P.C, Wang, A.H.J, Liang, P.H. | | Deposit date: | 2001-07-31 | | Release date: | 2001-08-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.
J.Biol.Chem., 276, 2001
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1KUI
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEQW. | | Descriptor: | CADMIUM ION, EQW, metalloproteinase | | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2002-01-22 | | Release date: | 2002-07-10 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
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1KUF
 | | High-resolution Crystal Structure of a Snake Venom Metalloproteinase from Taiwan Habu | | Descriptor: | CADMIUM ION, metalloproteinase | | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Yuann, J.M, Wang, A.H.J. | | Deposit date: | 2002-01-21 | | Release date: | 2002-07-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium.
Acta Crystallogr.,Sect.D, 58, 2002
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1KUK
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEKW. | | Descriptor: | CADMIUM ION, EKW, metalloproteinase | | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2002-01-22 | | Release date: | 2002-07-10 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
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1KUG
 | | Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with its endogenous inhibitor pENW | | Descriptor: | CADMIUM ION, ENW, metalloproteinase | | Authors: | Huang, K.F, Chiou, S.H, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2002-01-22 | | Release date: | 2002-07-10 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
Eur.J.Biochem., 269, 2002
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3EU0
 | | Crystal structure of the S-nitrosylated Cys215 of PTP1B | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 1 | | Authors: | Chu, H.M, Wang, A.H.J, Chen, Y.Y, Pan, K.T, Wang, D.L, Khoo, K.H, Meng, T.C. | | Deposit date: | 2008-10-09 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation
J.Biol.Chem., 283, 2008
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3X0U
 | | Crystal structure of PirB | | Descriptor: | Uncharacterized protein | | Authors: | Wang, H.C, Ko, T.P, Wang, A.H.J, Lo, C.F. | | Deposit date: | 2014-10-22 | | Release date: | 2015-08-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin.
Proc.Natl.Acad.Sci.USA, 112, 2015
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