6CME
 
 | | Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2 | | Descriptor: | LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2, ZINC ION | | Authors: | Stokes, P.H, Silva, A, Guss, J.M, Matthews, J.M. | | Deposit date: | 2018-03-04 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Mutation in a flexible linker modulates binding affinity for modular complexes.
Proteins, 87, 2019
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4IS1
 | | Crystal structure of ZNF217 bound to DNA | | Descriptor: | 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... | | Authors: | Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. | | Deposit date: | 2013-01-16 | | Release date: | 2013-02-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217.
J.Biol.Chem., 288, 2013
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2RGT
 | | Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1 | | Descriptor: | Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1, ... | | Authors: | Bhati, M, Lee, M, Guss, J.M, Matthews, J.M. | | Deposit date: | 2007-10-05 | | Release date: | 2008-08-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
Embo J., 27, 2008
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1PND
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1PNC
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1M35
 | | Aminopeptidase P from Escherichia coli | | Descriptor: | AMINOPEPTIDASE P, MANGANESE (II) ION | | Authors: | Graham, S.C, Lee, M, Freeman, H.C, Guss, J.M. | | Deposit date: | 2002-06-27 | | Release date: | 2003-05-06 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | An orthorhombic form of Escherichia coli aminopeptidase P at 2.4 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
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4FC3
 | | Crystal Structure of Human Methaemoglobin Complexed with the Second NEAT Domain of IsdH from Staphylococcus aureus | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... | | Authors: | Krishna Kumar, K, Jacques, D.A, Guss, J.M, Gell, D.A. | | Deposit date: | 2012-05-24 | | Release date: | 2013-05-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus
J.Biol.Chem., 289, 2014
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3G9Y
 | | Crystal structure of the second zinc finger from ZRANB2/ZNF265 bound to 6 nt ssRNA sequence AGGUAA | | Descriptor: | RNA (5'-R(*AP*GP*GP*UP*AP*A)-3'), ZINC ION, Zinc finger Ran-binding domain-containing protein 2 | | Authors: | Loughlin, F.E, McGrath, A.P, Lee, M, Guss, J.M, Mackay, J.P. | | Deposit date: | 2009-02-15 | | Release date: | 2009-03-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences
Proc.Natl.Acad.Sci.USA, 106, 2009
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1FSL
 | | FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE | | Descriptor: | LEGHEMOGLOBIN A, NICOTINIC ACID, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Ellis, P.J, Guss, J.M, Freeman, H.C. | | Deposit date: | 1995-12-12 | | Release date: | 1996-06-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of ferric soybean leghemoglobin a nicotinate at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 53, 1997
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4IJ2
 | | Human methemoglobin in complex with the second and third NEAT domains of IsdH from Staphylococcus aureus | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... | | Authors: | Dickson, C.F, Jacques, D.A, Guss, J.M, Gell, D.A. | | Deposit date: | 2012-12-21 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (4.24 Å) | | Cite: | Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus
J.Biol.Chem., 289, 2014
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6OM5
 | | Structure of a haemophore from Haemophilus haemolyticus | | Descriptor: | CHLORIDE ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Torrado, M, Walshe, J.L, Mackay, J.P, Guss, J.M, Gell, D.A. | | Deposit date: | 2019-04-18 | | Release date: | 2019-12-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae.
Mol.Microbiol., 113, 2020
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3MMK
 | | The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification | | Descriptor: | CHLORIDE ION, Fusion of LIM/homeobox protein Lhx4, linker, ... | | Authors: | Gadd, M.S, Langley, D.B, Guss, J.M, Matthews, J.M. | | Deposit date: | 2010-04-20 | | Release date: | 2011-07-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.157 Å) | | Cite: | The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification.
J.Biol.Chem., 2011
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1RUT
 | | Complex of LMO4 LIM domains 1 and 2 with the ldb1 LID domain | | Descriptor: | Fusion protein of Lmo4 protein and LIM domain-binding protein 1, ZINC ION | | Authors: | Deane, J.E, Ryan, D.P, Maher, M.J, Kwan, A.H.Y, Bacca, M, Mackay, J.P, Guss, J.M, Visvader, J.E, Matthews, J.M. | | Deposit date: | 2003-12-11 | | Release date: | 2004-10-12 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
Embo J., 23, 2004
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1AQT
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2BHC
 | | Na substituted E. coli Aminopeptidase P | | Descriptor: | CITRATE ANION, MAGNESIUM ION, SODIUM ION, ... | | Authors: | Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M. | | Deposit date: | 2005-01-10 | | Release date: | 2005-09-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
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2Z26
 | | Thr110Ala dihydroorotase from E. coli | | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, MALONATE ION, ... | | Authors: | Lee, M, Maher, M.J, Guss, J.M. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z28
 | | Thr109Val dihydroorotase from E. coli | | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | Authors: | Lee, M, Maher, M.J, Guss, J.M. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z24
 | | Thr110Ser dihydroorotase from E. coli | | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | Authors: | Lee, M, Maher, M.J, Guss, J.M. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z2B
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2Z25
 | | Thr110Val dihydroorotase from E. coli | | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | Authors: | Lee, M, Maher, M.J, Guss, J.M. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-09 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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1KCI
 | | Crystal Structure of 9-amino-N-[2-(4-morpholinyl)ethyl]-4-acridinecarboxamide Bound to d(CGTACG)2 | | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', 9-AMINO-N-[2-(4-MORPHOLINYL)ETHYL]-4-ACRIDINECARBOXAMIDE | | Authors: | Adams, A, Guss, J.M, Denny, W.A, Wakelin, L.P.G. | | Deposit date: | 2001-11-08 | | Release date: | 2002-02-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of 9-amino-N-[2-(4-morpholinyl)ethyl]-4-acridinecarboxamide bound to d(CGTACG)2: implications for structure-activity relationships of acridinecarboxamide topoisomerase poisons.
Nucleic Acids Res., 30, 2002
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1KSI
 | | CRYSTAL STRUCTURE OF A EUKARYOTIC (PEA SEEDLING) COPPER-CONTAINING AMINE OXIDASE AT 2.2A RESOLUTION | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | | Authors: | Wilce, M.C.J, Kumar, V, Freeman, H.C, Guss, J.M. | | Deposit date: | 1996-07-20 | | Release date: | 1997-12-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a eukaryotic (pea seedling) copper-containing amine oxidase at 2.2 A resolution.
Structure, 4, 1996
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1N51
 | | Aminopeptidase P in complex with the inhibitor apstatin | | Descriptor: | MANGANESE (II) ION, Xaa-Pro aminopeptidase, apstatin | | Authors: | Graham, S.C, Maher, M.J, Lee, M.H, Simmons, W.H, Freeman, H.C, Guss, J.M. | | Deposit date: | 2002-11-03 | | Release date: | 2003-12-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin.
Acta Crystallogr.,Sect.D, 60, 2004
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1JAW
 | | AMINOPEPTIDASE P FROM E. COLI LOW PH FORM | | Descriptor: | ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION | | Authors: | Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | | Deposit date: | 1997-12-22 | | Release date: | 1999-04-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 95, 1998
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3PGB
 | | Crystal structure of Aspergillus nidulans amine oxidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | McGrath, A.P, Guss, J.M. | | Deposit date: | 2010-11-01 | | Release date: | 2011-07-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure and Activity of Aspergillus nidulans Copper Amine Oxidase
Biochemistry, 50, 2011
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