3QNM
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![BU of 3qnm by Molmil](/molmil-images/mine/3qnm) | Haloalkane Dehalogenase Family Member from Bacteroides thetaiotaomicron of Unknown Function | Descriptor: | CHLORIDE ION, Haloacid dehalogenase-like hydrolase, MAGNESIUM ION | Authors: | Matthew, M.W, Ramagopal, U.A, Toro, R, Dickey, M, Sauder, J.M, Poulter, C.D, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2011-02-08 | Release date: | 2011-03-30 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Haloalkane Dehalogenase Family Member from Bacteroides thetaiotaomicron of Unknown Function To be Published
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3QVG
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![BU of 3qvg by Molmil](/molmil-images/mine/3qvg) | XRCC1 bound to DNA ligase | Descriptor: | DNA ligase 3, DNA repair protein XRCC1 | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | Deposit date: | 2011-02-25 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes. Nucleic Acids Res., 39, 2011
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3ALA
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![BU of 3ala by Molmil](/molmil-images/mine/3ala) | Crystal structure of vascular adhesion protein-1 in space group C2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ernberg, K.E, McGrath, A.P, Guss, J.M. | Deposit date: | 2010-07-29 | Release date: | 2010-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A new crystal form of human vascular adhesion protein 1 Acta Crystallogr.,Sect.F, 66, 2010
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1X8E
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![BU of 1x8e by Molmil](/molmil-images/mine/1x8e) | Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme | Descriptor: | Glucose-6-phosphate isomerase | Authors: | Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J. | Deposit date: | 2004-08-18 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis. J.Mol.Biol., 343, 2004
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1XMI
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![BU of 1xmi by Molmil](/molmil-images/mine/1xmi) | Crystal structure of human F508A NBD1 domain with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | Deposit date: | 2004-10-02 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
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1XOD
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![BU of 1xod by Molmil](/molmil-images/mine/1xod) | Crystal structure of X. tropicalis Spred1 EVH-1 domain | Descriptor: | GLYCEROL, Spred1 | Authors: | Harmer, N.J, Sivak, J.M, Amaya, E, Blundell, T.L. | Deposit date: | 2004-10-06 | Release date: | 2005-01-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | 1.15A Crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family Febs Lett., 579, 2005
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3Q7E
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![BU of 3q7e by Molmil](/molmil-images/mine/3q7e) | |
1XOK
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![BU of 1xok by Molmil](/molmil-images/mine/1xok) | crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide | Descriptor: | BROMIDE ION, Coat protein, alfalfa mosaic virus RNA 3' UTR | Authors: | Guogas, L.M, Filman, D.J, Hogle, J.M, Gehrke, L. | Deposit date: | 2004-10-06 | Release date: | 2005-01-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication. Science, 306, 2004
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1XQ9
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1XGD
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![BU of 1xgd by Molmil](/molmil-images/mine/1xgd) | Apo R268A human aldose reductase | Descriptor: | Aldose reductase | Authors: | Brownlee, J.M, Bohren, K.M, Milne, A.C, Gabbay, K.H, Harrison, D.H.T. | Deposit date: | 2004-09-16 | Release date: | 2005-03-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism Biochim.Biophys.Acta, 1748, 2005
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3ENM
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![BU of 3enm by Molmil](/molmil-images/mine/3enm) | The structure of the MAP2K MEK6 reveals an autoinhibitory dimer | Descriptor: | 1,2-ETHANEDIOL, Dual specificity mitogen-activated protein kinase kinase 6, GLYCEROL, ... | Authors: | Min, X, Akella, R, He, H, Humphreys, J.M, Tsutakawa, S, Lee, S.-J, Tainer, J.A, Cobb, M.H, Goldsmith, E.J. | Deposit date: | 2008-09-25 | Release date: | 2009-03-03 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The structure of the MAP2K MEK6 reveals an autoinhibitory dimer Structure, 17, 2009
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1XPR
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![BU of 1xpr by Molmil](/molmil-images/mine/1xpr) | Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-formylbicyclomycin (FB) | Descriptor: | 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3', 5A-FORMYLBICYCLOMYCIN, MAGNESIUM ION, ... | Authors: | Skordalakes, E, Brogan, A.P, Park, B.S, Kohn, H, Berger, J.M. | Deposit date: | 2004-10-09 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural mechanism of inhibition of the rho transcription termination factor by the antibiotic bicyclomycin Structure, 13, 2005
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3E2V
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![BU of 3e2v by Molmil](/molmil-images/mine/3e2v) | Crystal structure of an uncharacterized amidohydrolase from Saccharomyces cerevisiae | Descriptor: | 3'-5'-exonuclease, GLYCEROL, MAGNESIUM ION | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Hu, S, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-08-06 | Release date: | 2008-08-26 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of an uncharacterized amidohydrolase from Saccharomyces cerevisiae To be Published
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1XUF
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![BU of 1xuf by Molmil](/molmil-images/mine/1xuf) | TRYPSIN-BABIM-ZN+2, PH 8.2 | Descriptor: | BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE ZINC, CALCIUM ION, TRYPSIN | Authors: | Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M. | Deposit date: | 1997-10-10 | Release date: | 1998-12-16 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391, 1998
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3R91
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![BU of 3r91 by Molmil](/molmil-images/mine/3r91) | Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity. | Descriptor: | (6S)-4,6,15,15,18-pentamethyl-5,17-dioxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-12,8-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide, Heat shock protein HSP 90-alpha | Authors: | Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Nittoli, T, Otteng, M, Ingalls, C, Golas, J.M, Liu, H, Lucas, J, Boschelli, F, Vogan, E, Hu, Y, Levin, J.I. | Deposit date: | 2011-03-24 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.579 Å) | Cite: | Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity. Bioorg.Med.Chem.Lett., 21, 2011
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1XYR
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![BU of 1xyr by Molmil](/molmil-images/mine/1xyr) | Poliovirus 135S cell entry intermediate | Descriptor: | Genome polyprotein, Coat protein VP1, Coat protein VP2, ... | Authors: | Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M. | Deposit date: | 2004-11-10 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J.Virol., 79, 2005
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3EIC
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![BU of 3eic by Molmil](/molmil-images/mine/3eic) | X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with UDP | Descriptor: | MAGNESIUM ION, Nucleoside diphosphate kinase, URIDINE-5'-DIPHOSPHATE | Authors: | Jeudy, S, Lartigue, A, Claverie, J.M, Abergel, C. | Deposit date: | 2008-09-15 | Release date: | 2009-06-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J.Virol., 83, 2009
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3EJM
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![BU of 3ejm by Molmil](/molmil-images/mine/3ejm) | Crystal structure of the mimivirus NDK +Kpn mutant complexed with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase | Authors: | Jeudy, S, Lartigue, A, Claverie, J.M, Abergel, C. | Deposit date: | 2008-09-18 | Release date: | 2009-08-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J.Virol., 83, 2009
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3RKP
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![BU of 3rkp by Molmil](/molmil-images/mine/3rkp) | Crystal structure of BcpA*(D312A), the major pilin subunit of Bacillus cereus | Descriptor: | Collagen adhesion protein | Authors: | Hendrickx, A.P, Poor, C.B, Jureller, J.E, Budzik, J.M, He, C, Schneewind, O. | Deposit date: | 2011-04-18 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.243 Å) | Cite: | Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Mol.Microbiol., 85, 2012
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1XZ4
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![BU of 1xz4 by Molmil](/molmil-images/mine/1xz4) | Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt | Descriptor: | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kavanaugh, J.S, Rogers, P.H, Arnone, A, Hui, H.L, Wierzba, A, DeYoung, A, Kwiatkowski, L.D, Noble, R.W, Juszczak, L.J, Peterson, E.S, Friedman, J.M. | Deposit date: | 2004-11-11 | Release date: | 2004-11-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Intersubunit interactions associated with tyr42alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin Biochemistry, 44, 2005
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3RTO
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![BU of 3rto by Molmil](/molmil-images/mine/3rto) | Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure | Descriptor: | Insulin, ZINC ION | Authors: | Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. | Deposit date: | 2011-05-03 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
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3B2N
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![BU of 3b2n by Molmil](/molmil-images/mine/3b2n) | Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus | Descriptor: | SODIUM ION, Uncharacterized protein Q99UF4 | Authors: | Malashkevich, V.N, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-10-18 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus. To be Published
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3B1V
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![BU of 3b1v by Molmil](/molmil-images/mine/3b1v) | Crystal structure of an S. thermophilus NFeoB E67A mutant bound to mGMPPNP | Descriptor: | 3'-O-(N-methylanthraniloyl)-beta:gamma-imidoguanosine-5'-triphosphate, CHLORIDE ION, Ferrous iron uptake transporter protein B, ... | Authors: | Ash, M.R, Maher, M.J, Guss, J.M, Jormakka, M. | Deposit date: | 2011-07-15 | Release date: | 2011-11-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB Acta Crystallogr.,Sect.D, 67, 2011
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3QK7
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![BU of 3qk7 by Molmil](/molmil-images/mine/3qk7) | Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001 | Descriptor: | Transcriptional regulators | Authors: | Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2011-01-31 | Release date: | 2011-02-09 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001 To be Published
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3B4T
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![BU of 3b4t by Molmil](/molmil-images/mine/3b4t) | Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340 | Descriptor: | PHOSPHATE ION, Ribonuclease PH | Authors: | Antczak, A.J, Berger, J.M, Lekin, T, Segelke, B.W, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2007-10-24 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis. To be Published
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