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2IUX
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BU of 2iux by Molmil
Human tACE mutant g1234
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, ...
Authors:Watermeyer, J.M, Swell, B.T, Natesh, R, Corradi, H.R, Acharya, K.R, Sturrock, E.D.
Deposit date:2006-06-07
Release date:2006-10-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Testis Ace Glycosylation Mutants and Evidence for Conserved Domain Movement.
Biochemistry, 45, 2006
2IDC
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BU of 2idc by Molmil
Structure of the Histone H3-Asf1 Chaperone Interaction
Descriptor: ANTI-SILENCING PROTEIN 1 AND HISTONE H3 CHIMERA
Authors:Antczak, A.J, Tsubota, T, Kaufman, P.D, Berger, J.M.
Deposit date:2006-09-14
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the yeast histone H3-ASF1 interaction: implications for chaperone mechanism, species-specific interactions, and epigenetics.
Bmc Struct.Biol., 6, 2006
2IQ0
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BU of 2iq0 by Molmil
Crystal Structure of Aldose Reductase complexed with Hexanoic Acid
Descriptor: Aldose reductase, HEXANOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Harrison, D.H.T, Brownlee, J.M.
Deposit date:2006-10-12
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
1C4Z
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BU of 1c4z by Molmil
STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY
Descriptor: UBIQUITIN CONJUGATING ENZYME E2, UBIQUITIN-PROTEIN LIGASE E3A
Authors:Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P.
Deposit date:1999-10-14
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
1UB1
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BU of 1ub1 by Molmil
Solution structure of the matrix attachment region-binding domain of chicken MeCP2
Descriptor: attachment region binding protein
Authors:Heitmann, B, Maurer, T, Weitzel, J.M, Stratling, W.H, Kalbitzer, H.R, Brunner, E, Structural Proteomics in Europe (SPINE)
Deposit date:2003-03-27
Release date:2003-08-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the matrix attachment region-binding domain of chicken MeCP2
EUR.J.BIOCHEM., 270, 2003
2K1G
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BU of 2k1g by Molmil
Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162
Descriptor: Lipoprotein spr
Authors:Aramini, J.M, Rossi, P, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.
Biochemistry, 47, 2008
1TVK
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BU of 1tvk by Molmil
The binding mode of epothilone A on a,b-tubulin by electron crystallography
Descriptor: EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Nettles, J.H, Li, H, Cornett, B, Krahn, J.M, Snyder, J.P, Downing, K.H.
Deposit date:2004-06-29
Release date:2004-09-14
Last modified:2023-08-23
Method:ELECTRON CRYSTALLOGRAPHY (2.89 Å)
Cite:The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography
Science, 305, 2004
1UCI
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BU of 1uci by Molmil
Mutants of RNase Sa
Descriptor: Guanyl-specific ribonuclease Sa, SULFATE ION
Authors:Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N.
Deposit date:2003-04-15
Release date:2003-09-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
2JVW
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BU of 2jvw by Molmil
Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117
Descriptor: Uncharacterized protein
Authors:Aramini, J.M, Rossi, P, Wang, D, Nwosu, C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-26
Release date:2007-10-16
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.
Proteins, 79, 2011
2JVD
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BU of 2jvd by Molmil
Solution NMR structure of the folded N-terminal fragment of UPF0291 protein ynzC from Bacillus subtilis. Northeast Structural Genomics target SR384-1-46
Descriptor: UPF0291 protein ynzC
Authors:Aramini, J.M, Sharma, S, Huang, Y.J, Zhao, L, Owens, L.A, Stokes, K, Jiang, M, Xiao, R, Baran, M.C, Swapna, G.V.T, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-18
Release date:2007-10-02
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis.
Proteins, 72, 2008
1B13
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BU of 1b13 by Molmil
CLOSTRIDIUM PASTEURIANUM RUBREDOXIN G10A MUTANT
Descriptor: FE (III) ION, PROTEIN (RUBREDOXIN)
Authors:Maher, M.J, Guss, J.M, Wilce, M.C.J, Wedd, A.G.
Deposit date:1998-11-26
Release date:1999-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rubredoxin from Clostridium pasteurianum. Structures of G10A, G43A and G10VG43A mutant proteins. Mutation of conserved glycine 10 to valine causes the 9-10 peptide link to invert.
Acta Crystallogr.,Sect.D, 55, 1999
2JD4
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BU of 2jd4 by Molmil
Mouse laminin alpha1 chain, domains LG4-5
Descriptor: CHLORIDE ION, LAMININ SUBUNIT ALPHA-1, MAGNESIUM ION
Authors:Harrison, D, Hussain, S.A, Combs, A.C, Ervasti, J.M, Yurchenco, P.D, Hohenester, E.
Deposit date:2007-01-04
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure and Cell Surface Anchorage Sites of Laminin {Alpha}1Lg4-5.
J.Biol.Chem., 282, 2007
1RJN
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BU of 1rjn by Molmil
The Crystal Structure of MenB (Rv0548c) from Mycobacterium tuberculosis in Complex with the CoA Portion of Naphthoyl CoA
Descriptor: 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, COENZYME A, menB
Authors:Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-11-19
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms.
Acta Crystallogr.,Sect.D, 61, 2005
1R48
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BU of 1r48 by Molmil
Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
Descriptor: Proline/betaine transporter
Authors:Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
1R7I
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BU of 1r7i by Molmil
HMG-CoA Reductase from P. mevalonii, native structure at 2.2 angstroms resolution.
Descriptor: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, SULFATE ION
Authors:Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V.
Deposit date:2003-10-21
Release date:2003-11-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-COA Reductase.
To be Published
1RS4
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BU of 1rs4 by Molmil
DHNA, 7,8-Dihydroneopterin Aldolase complexed with 3-(5-Amino-7-hydroxy-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl)-N-(3,5-dichlorobenzyl)-benzamide
Descriptor: 3-(5-AMINO-7-HYDROXY-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-2-YL)-N-(3,5-DICHLOROBENZYL)-BENZAMIDE, Dihydroneopterin aldolase
Authors:Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A.
Deposit date:2003-12-09
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
J.Med.Chem., 47, 2004
1R9I
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BU of 1r9i by Molmil
NMR Solution Structure of PIIIA toxin, NMR, 20 structures
Descriptor: Mu-conotoxin PIIIA
Authors:Nielsen, K.J, Watson, M, Adams, D.J, Hammarstrom, A.K, Gage, P.W, Hill, J.M, Craik, D.J, Thomas, L, Adams, D, Alewood, P.F, Lewis, R.J.
Deposit date:2003-10-30
Release date:2003-11-18
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels
J.Biol.Chem., 277, 2002
2JB7
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BU of 2jb7 by Molmil
PAE2307 with AMP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Rajasekaran, K, Lott, J.S, Johnston, J.M.
Deposit date:2006-12-04
Release date:2008-08-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Pae2307 a Phosphotransferase
To be Published
1RJM
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BU of 1rjm by Molmil
Crystal Structure of MenB (Rv0548c) from Mycobacterium tuberculosis
Descriptor: 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, MenB
Authors:Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-11-19
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms.
Acta Crystallogr.,Sect.D, 61, 2005
1AXC
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BU of 1axc by Molmil
HUMAN PCNA
Descriptor: P21/WAF1, PCNA
Authors:Gulbis, J.M, Kuriyan, J.
Deposit date:1997-10-14
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
1RSI
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BU of 1rsi by Molmil
DHNA complex with 2-Amino-5-bromo-3-hydroxy-6-phenylpyrimidine
Descriptor: 2-AMINO-5-BROMO-6-PHENYLPYRIMIDIN-4-OL, Dihydroneopterin aldolase
Authors:Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A.
Deposit date:2003-12-09
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
J.Med.Chem., 47, 2004
2KIM
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BU of 2kim by Molmil
1.7-mm microcryoprobe solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247.
Descriptor: O6-methylguanine-DNA methyltransferase
Authors:Aramini, J.M, Belote, R.L, Ciccosanti, C.T, Jiang, M, Rost, B, Nair, R, Swapna, G.V.T, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-05-07
Release date:2009-07-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247.
To be Published
2K9D
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BU of 2k9d by Molmil
Solution structure of the domain X of measle phosphoprotein
Descriptor: Phosphoprotein
Authors:Gely, S, Bernard, C, Bourhis, J.M, Longhi, S, Darbon, H.
Deposit date:2008-10-08
Release date:2009-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR.
Febs Lett., 583, 2009
1R31
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BU of 1r31 by Molmil
HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA
Descriptor: (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, ...
Authors:Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V.
Deposit date:2003-09-30
Release date:2003-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase.
To be Published
2KIB
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BU of 2kib by Molmil
Protein Fibril
Descriptor: NFGAIL segment from human islet amyloid polypeptide
Authors:Nielsen, J.T, Bjerring, M, Jeppesen, M.D, Pedersen, R.O, Pedersen, J.M, Hein, K.L, Vosegaard, T, Skrydstrup, T, Otzen, D.E, Nielsen, N.
Deposit date:2009-05-01
Release date:2009-09-08
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Unique identification of supramolecular structures in amyloid fibrils by solid-state NMR spectroscopy.
Angew.Chem.Int.Ed.Engl., 48, 2009

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