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5A1N
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BU of 5a1n by Molmil
The crystal structure of the GST-like domains complex of EPRS-AIMP2 mutant S156D
Descriptor: AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2, BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE, GLYCEROL
Authors:Cho, H.Y, Choi, Y.S, Kang, B.S.
Deposit date:2015-05-03
Release date:2016-06-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase.
J.Mol.Biol., 2019
2OLG
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BU of 2olg by Molmil
Crystal structure of the serine protease domain of prophenoloxidase activating factor-I in a zymogen form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Pro-phenoloxidase activating enzyme-I, ...
Authors:Ha, N.C, Piao, S.
Deposit date:2007-01-19
Release date:2007-02-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the serine protease domain of prophenoloxidase activating factor-I
J.Biol.Chem., 282, 2007
8ERC
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BU of 8erc by Molmil
Human Membrane-bound O-acyltransferase 7
Descriptor: Lysophospholipid acyltransferase 7
Authors:Wang, K, Liao, M, Farese, R.V, Walther, T.C.
Deposit date:2022-10-11
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.
Nat Commun, 14, 2023
6ICI
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BU of 6ici by Molmil
Crystal structure of human MICAL3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3
Authors:Hwang, K.Y, Kim, J.S.
Deposit date:2018-09-06
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
5H6Z
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BU of 5h6z by Molmil
Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe
Descriptor: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, SET domain-containing protein 7, ...
Authors:Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E.
Deposit date:2016-11-15
Release date:2017-11-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis.
Structure, 27, 2019
4R3Z
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BU of 4r3z by Molmil
Crystal structure of human ArgRS-GlnRS-AIMP1 complex
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ...
Authors:Fu, Y, Kim, Y, Cho, Y.
Deposit date:2014-08-18
Release date:2014-10-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.033 Å)
Cite:Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation
Proc.Natl.Acad.Sci.USA, 111, 2014
6B0F
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BU of 6b0f by Molmil
ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102
Descriptor: Estrogen receptor, GLYCEROL, LSZ102
Authors:Kirby, C.A, Baird, J.
Deposit date:2017-09-14
Release date:2018-04-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
J. Med. Chem., 61, 2018
4K86
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BU of 4k86 by Molmil
Crystal structure of human prolyl-tRNA synthetase (apo form)
Descriptor: Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
4K87
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BU of 4k87 by Molmil
Crystal structure of human prolyl-tRNA synthetase (substrate bound form)
Descriptor: ADENOSINE, PROLINE, Proline--tRNA ligase, ...
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
2MNU
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BU of 2mnu by Molmil
Backbone and side chain 1H, 13C, and 15N Chemical Shift Assignments for EDB and specific binding aptide
Descriptor: APT, EDB
Authors:Suh, J, Yu, T.
Deposit date:2014-04-10
Release date:2014-09-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An Unusual Protein-Protein Interaction through Coupled Unfolding and Binding
Angew.Chem.Int.Ed.Engl., 53, 2014
4K88
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BU of 4k88 by Molmil
Crystal structure of human prolyl-tRNA synthetase (halofuginone bound form)
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
6OWL
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BU of 6owl by Molmil
RNA oligonucleotides with 3'-arabino guanosine co-crystallized with GMP
Descriptor: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*R)-3'), RNA (5'-R(P*G)-3')
Authors:Szostak, J.W, Kim, S, Zhang, W.
Deposit date:2019-05-10
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2'-Deoxynucleotides.
J.Am.Chem.Soc., 142, 2020
5T1F
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BU of 5t1f by Molmil
Crystal structure of Phaeospaeria nodrum fructosyl peptide oxidase mutant Asn56Ala
Descriptor: ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Uncharacterized protein
Authors:Yoshida, H, Shimasaki, T, Kamitori, S, Sode, K.
Deposit date:2016-08-19
Release date:2017-06-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction
Sci Rep, 7, 2017
5T1E
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BU of 5t1e by Molmil
Crystal structure of Phaeospaeria nodrum fructosyl peptide oxidase
Descriptor: ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Uncharacterized protein
Authors:Yoshida, H, Shimasaki, T, Kamitori, S, Sode, K.
Deposit date:2016-08-19
Release date:2017-06-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction
Sci Rep, 7, 2017
6IJQ
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BU of 6ijq by Molmil
Solution structure of BCL-XL bound to P73-TAD peptide
Descriptor: Bcl-2-like protein 1,Bcl-2-like protein 1, Tumor protein p73
Authors:Yoon, M.-K, Ha, J.-H, Lee, M.-S, Chi, S.-W.
Deposit date:2018-10-11
Release date:2018-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
J. Biol. Chem., 293, 2018
8DA0
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BU of 8da0 by Molmil
Crystal structure of Mamba alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
Descriptor: ACETATE ION, Alpha-elapitoxin-Dpp2d, Centi-3FTX-D09 Fab heavy chain, ...
Authors:Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
Deposit date:2022-06-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8D9Y
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BU of 8d9y by Molmil
Crystal structure of Taipan alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Centi-3FTX-D09 Fab heavy chain, ...
Authors:Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
Deposit date:2022-06-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8DA1
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BU of 8da1 by Molmil
Crystal structure of Krait alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
Descriptor: Alpha-bungarotoxin, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain
Authors:Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
Deposit date:2022-06-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8D9Z
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BU of 8d9z by Molmil
Crystal structure of Cobra alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
Descriptor: ACETATE ION, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain, ...
Authors:Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
Deposit date:2022-06-12
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
3II5
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BU of 3ii5 by Molmil
The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
Descriptor: B-Raf proto-oncogene serine/threonine-protein kinase, N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION
Authors:Xu, W, Breger, D, Torres, N, Dutia, M, Powell, D, Ciszewski, G.
Deposit date:2009-07-31
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
5E1T
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BU of 5e1t by Molmil
Crystal structure of TRAF1 TRAF domain
Descriptor: TNF receptor-associated factor 1
Authors:Park, H.H, Kim, C.M.
Deposit date:2015-09-30
Release date:2016-12-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway
Sci Rep, 6, 2016
4E37
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BU of 4e37 by Molmil
Crystal Structure of P. aeruginosa catalase, KatA tetramer
Descriptor: Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE
Authors:VanderWielen, B.D, Wilson, J.J, Kovall, R.A.
Deposit date:2012-03-09
Release date:2013-03-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:KatA, the Major Catalase in Pseudomonas aeruginosa, Assists in Protecting Anaerobic Bacteria From Metabolic and Exogenous Nitric Oxide
To be Published
1DU3
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BU of 1du3 by Molmil
Crystal structure of TRAIL-SDR5
Descriptor: DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND, ZINC ION
Authors:Cha, S.-S, Sung, B.-J, Oh, B.-H.
Deposit date:2000-01-14
Release date:2000-09-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
J.Biol.Chem., 275, 2000
5YC1
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BU of 5yc1 by Molmil
TRAF4_GPIb complex
Descriptor: GPIb peptide, TNF receptor-associated factor 4
Authors:Park, H.H, Kim, C.M.
Deposit date:2017-09-06
Release date:2017-10-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Molecular basis for unique specificity of human TRAF4 for platelets GPIb beta and GPVI
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2HWC
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BU of 2hwc by Molmil
A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
Authors:Kim, K.H, Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-11-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993

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