2ZTA
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![BU of 2zta by Molmil](/molmil-images/mine/2zta) | X-RAY STRUCTURE OF THE GCN4 LEUCINE ZIPPER, A TWO-STRANDED, PARALLEL COILED COIL | Descriptor: | GCN4 LEUCINE ZIPPER | Authors: | O'Shea, E.K, Klemm, J.D, Kim, P.S, Alber, T. | Deposit date: | 1991-07-05 | Release date: | 1992-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science, 254, 1991
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1UW6
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![BU of 1uw6 by Molmil](/molmil-images/mine/1uw6) | X-ray structure of acetylcholine binding protein (AChBP) in complex with nicotine | Descriptor: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, ACETYLCHOLINE-BINDING PROTEIN | Authors: | Celie, P.H.N, Van Rossum-fikkert, S.E, Van Dijk, W.J, Brejc, K, Smit, A.B, Sixma, T.K. | Deposit date: | 2004-01-30 | Release date: | 2004-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures Neuron, 41, 2004
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2HB4
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![BU of 2hb4 by Molmil](/molmil-images/mine/2hb4) | Structure of HIV Protease NL4-3 in an Unliganded State | Descriptor: | MAGNESIUM ION, Protease, R-1,2-PROPANEDIOL | Authors: | Heaslet, H, Tam, K, Elder, J.H, Stout, C.D. | Deposit date: | 2006-06-13 | Release date: | 2007-06-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63, 2007
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1BJG
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![BU of 1bjg by Molmil](/molmil-images/mine/1bjg) | D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING | Descriptor: | 5,10-METHYLENE-6-HYDROFOLIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Sage, C.R, Michelitsch, M.D, Finer-Moore, J, Stroud, R.M. | Deposit date: | 1998-06-25 | Release date: | 1998-11-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry, 37, 1998
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1DNA
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![BU of 1dna by Molmil](/molmil-images/mine/1dna) | D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Sage, C.R, Michelitsch, M.D, Finer-Moore, J, Stroud, R.M. | Deposit date: | 1998-06-25 | Release date: | 1998-11-04 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry, 37, 1998
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1SZB
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![BU of 1szb by Molmil](/molmil-images/mine/1szb) | Crystal structure of the human MBL-associated protein 19 (MAp19) | Descriptor: | CALCIUM ION, mannose binding lectin-associated serine protease-2 related protein, MAp19 (19kDa) | Authors: | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | Deposit date: | 2004-04-05 | Release date: | 2004-06-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin J.Biol.Chem., 279, 2004
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2O17
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![BU of 2o17 by Molmil](/molmil-images/mine/2o17) | Pectate lyase bound to hexasaccharide | Descriptor: | CALCIUM ION, Pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Pickersgill, R.W, Seyedarabi, A. | Deposit date: | 2006-11-28 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry, 49, 2010
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2NZM
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![BU of 2nzm by Molmil](/molmil-images/mine/2nzm) | Hexasaccharide I bound to Bacillus subtilis pectate lyase | Descriptor: | CALCIUM ION, Pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Pickersgill, R.W, Seyedarabi, A. | Deposit date: | 2006-11-24 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry, 49, 2010
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2O04
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![BU of 2o04 by Molmil](/molmil-images/mine/2o04) | Pectate lyase bound to hexasaccharide compound II | Descriptor: | CALCIUM ION, Pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Pickersgill, R.W, Seyedarabi, A. | Deposit date: | 2006-11-27 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry, 49, 2010
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2O1D
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![BU of 2o1d by Molmil](/molmil-images/mine/2o1d) | Pectate lyase bound to trisaccharide | Descriptor: | CALCIUM ION, Pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Pickersgill, R.W, Seyedarabi, A. | Deposit date: | 2006-11-28 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry, 49, 2010
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2O0V
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![BU of 2o0v by Molmil](/molmil-images/mine/2o0v) | Pectate lyase bound to hexasaccharide compound III | Descriptor: | CALCIUM ION, Pectate lyase, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Pickersgill, R.W, Seyedarabi, A. | Deposit date: | 2006-11-28 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase. Biochemistry, 49, 2010
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2WUL
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![BU of 2wul by Molmil](/molmil-images/mine/2wul) | CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Roos, A.K, Johansson, C, Guo, K, Yue, W.W, Pike, A.C.W, Cooper, C.D.O, Pilka, E.S, Kavanagh, K.L, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | Deposit date: | 2009-10-06 | Release date: | 2009-10-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of Human Glrx5: Iron Sulphur Cluster Coordination, Tetrameric Assembly and Monomer Activity. Biochem.J., 433, 2011
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1LQF
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![BU of 1lqf by Molmil](/molmil-images/mine/1lqf) | Structure of PTP1b in Complex with a Peptidic Bisphosphonate Inhibitor | Descriptor: | N-BENZOYL-L-GLUTAMYL-[4-PHOSPHONO(DIFLUOROMETHYL)]-L-PHENYLALANINE-[4-PHOSPHONO(DIFLUORO-METHYL)]-L-PHENYLALANINEAMIDE, protein-tyrosine phosphatase, non-receptor type 1 | Authors: | Asante-Appiah, E, Patel, S, Dufresne, C, Scapin, G. | Deposit date: | 2002-05-10 | Release date: | 2002-07-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates. Biochemistry, 41, 2002
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3DXJ
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![BU of 3dxj by Molmil](/molmil-images/mine/3dxj) | Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M, ... | Authors: | Das, K, Arnold, E. | Deposit date: | 2008-07-24 | Release date: | 2008-10-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The RNA polymerase "switch region" is a target for inhibitors. Cell(Cambridge,Mass.), 135, 2008
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1JLO
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![BU of 1jlo by Molmil](/molmil-images/mine/1jlo) | |
1JLP
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![BU of 1jlp by Molmil](/molmil-images/mine/1jlp) | |
1NCE
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![BU of 1nce by Molmil](/molmil-images/mine/1nce) | Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717 | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | Authors: | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | Deposit date: | 2002-12-05 | Release date: | 2002-12-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The only active mutant of thymidylate synthase D169, a residue far from the
site of methyl transfer, demonstrates the exquisite nature of enzyme
specificity. Protein Eng., 16, 2003
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