7X3E
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![BU of 7x3e by Molmil](/molmil-images/mine/7x3e) | Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 9A3 (CVB1-pre-A:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X2G
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![BU of 7x2g by Molmil](/molmil-images/mine/7x2g) | Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb nAb 2E6 (CVB1-E:2E6) | Descriptor: | 2E6 heavy chain, 2E6 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-25 | Release date: | 2022-09-28 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X2O
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![BU of 7x2o by Molmil](/molmil-images/mine/7x2o) | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6) | Descriptor: | 2E6 heavy chain, 2E6 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-25 | Release date: | 2022-09-28 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X49
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![BU of 7x49 by Molmil](/molmil-images/mine/7x49) | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 9A3) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3D
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![BU of 7x3d by Molmil](/molmil-images/mine/7x3d) | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 9A3 (CVB1-M:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7FJ1
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![BU of 7fj1 by Molmil](/molmil-images/mine/7fj1) | Cryo-EM structure of pseudorabies virus C-capsid | Descriptor: | Capsid vertex component 1, DNA packaging tegument protein UL25, Major capsid protein, ... | Authors: | Zheng, Q, Li, S, Zha, Z, Sun, H. | Deposit date: | 2021-08-02 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (4.43 Å) | Cite: | Structures of pseudorabies virus capsids. Nat Commun, 13, 2022
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7FJ3
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![BU of 7fj3 by Molmil](/molmil-images/mine/7fj3) | Cryo-EM structure of PRV A-capid | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Zheng, Q, Li, S, Zha, Z, Sun, H. | Deposit date: | 2021-08-02 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (4.53 Å) | Cite: | Structures of pseudorabies virus capsids. Nat Commun, 13, 2022
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3RL8
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![BU of 3rl8 by Molmil](/molmil-images/mine/3rl8) | Crystal structure of hDLG1-PDZ2 complexed with APC | Descriptor: | 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1 | Authors: | Zhang, Z, Li, H, Wu, G. | Deposit date: | 2011-04-19 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. Plos One, 6, 2011
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2XCY
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![BU of 2xcy by Molmil](/molmil-images/mine/2xcy) | Crystal structure of Aspergillus fumigatus sialidase | Descriptor: | CHLORIDE ION, EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE, ... | Authors: | Telford, J.C, Yeung, J, Xu, G, Bennet, A, Moore, M.M, Taylor, G.L. | Deposit date: | 2010-04-27 | Release date: | 2010-05-12 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights. J.Biol.Chem., 286, 2011
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4LY9
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![BU of 4ly9 by Molmil](/molmil-images/mine/4ly9) | Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate | Descriptor: | (2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | Authors: | Jordan, S.R. | Deposit date: | 2013-07-30 | Release date: | 2013-11-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. Nature, 504, 2013
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2O9B
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![BU of 2o9b by Molmil](/molmil-images/mine/2o9b) | Crystal Structure of Bacteriophytochrome chromophore binding domain | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | Authors: | Wagner, J.R, Brunzelle, J.S, Vierstra, R.D, Forest, K.T. | Deposit date: | 2006-12-13 | Release date: | 2007-03-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution. J.Biol.Chem., 282, 2007
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2O5J
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![BU of 2o5j by Molmil](/molmil-images/mine/2o5j) | |
7WA9
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![BU of 7wa9 by Molmil](/molmil-images/mine/7wa9) | |
7Y3L
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![BU of 7y3l by Molmil](/molmil-images/mine/7y3l) | Structure of SALL3 ZFC4 bound with 12 bp AT-rich dsDNA | Descriptor: | DNA (12-mer), Sal-like protein 3, ZINC ION | Authors: | Ru, W, Xu, C. | Deposit date: | 2022-06-11 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif. J.Biol.Chem., 298, 2022
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7Y3I
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![BU of 7y3i by Molmil](/molmil-images/mine/7y3i) | Structure of DNA bound SALL4 | Descriptor: | DNA (12-mer), Sal-like protein 4, ZINC ION | Authors: | Ru, W, Xu, C. | Deposit date: | 2022-06-10 | Release date: | 2022-10-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif. J.Biol.Chem., 298, 2022
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7Y3K
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![BU of 7y3k by Molmil](/molmil-images/mine/7y3k) | Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | Authors: | Ru, W, Xu, C. | Deposit date: | 2022-06-11 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif. J.Biol.Chem., 298, 2022
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7Y3M
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![BU of 7y3m by Molmil](/molmil-images/mine/7y3m) | Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | Authors: | Ru, W, Xu, C. | Deposit date: | 2022-06-11 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.723 Å) | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif. J.Biol.Chem., 298, 2022
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4MRO
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![BU of 4mro by Molmil](/molmil-images/mine/4mro) | Human GKRP bound to AMG-5980 and S6P | Descriptor: | 2-(4-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | Authors: | St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L, Kunz, K, Michelsen, K, Nishimura, N, Pennington, L.D, Poon, S.F, Sivits, G, Stec, M.M, Tamayo, N, Van, G, Yang, K, Norman, M.H, Fotsch, C, LLoyd, D.J, Hale, C. | Deposit date: | 2013-09-17 | Release date: | 2014-05-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles. J.Med.Chem., 57, 2014
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7EL6
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![BU of 7el6 by Molmil](/molmil-images/mine/7el6) | Structure of SMCR8 bound FEM1B | Descriptor: | Protein fem-1 homolog B,Guanine nucleotide exchange protein SMCR8 | Authors: | Zhao, S, Xu, C. | Deposit date: | 2021-04-08 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structural insights into SMCR8 C-degron recognition by FEM1B. Biochem.Biophys.Res.Commun., 557, 2021
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3RER
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![BU of 3rer by Molmil](/molmil-images/mine/3rer) | Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP | Descriptor: | 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wang, W.W, Wu, J.H, Shi, Y.Y. | Deposit date: | 2011-04-05 | Release date: | 2011-10-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Cooperation of Escherichia coli Hfq hexamers in DsrA binding. Genes Dev., 25, 2011
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2O9C
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![BU of 2o9c by Molmil](/molmil-images/mine/2o9c) | Crystal Structure of Bacteriophytochrome chromophore binding domain at 1.45 angstrom resolution | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | Authors: | Wagner, J.R, Brunzelle, J.S, Vierstra, R.D, Forest, K.T. | Deposit date: | 2006-12-13 | Release date: | 2007-03-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution. J.Biol.Chem., 282, 2007
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3BT1
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![BU of 3bt1 by Molmil](/molmil-images/mine/3bt1) | Structure of urokinase receptor, urokinase and vitronectin complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ... | Authors: | Huang, M. | Deposit date: | 2007-12-27 | Release date: | 2008-03-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes Nat.Struct.Mol.Biol., 15, 2008
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5FD2
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![BU of 5fd2 by Molmil](/molmil-images/mine/5fd2) | |
3SWJ
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![BU of 3swj by Molmil](/molmil-images/mine/3swj) | Crystal structure of Campylobacter jejuni ChuZ | Descriptor: | AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein | Authors: | Hu, Y. | Deposit date: | 2011-07-14 | Release date: | 2011-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | Crystal structure of Campylobacter jejuni ChuZ: a split-barrel family heme oxygenase with a novel heme-binding mode. Biochem.Biophys.Res.Commun., 415, 2011
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4O91
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![BU of 4o91 by Molmil](/molmil-images/mine/4o91) | Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1 | Descriptor: | Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide | Authors: | Gurbani, D, Hunter, J.C, Tan, L, Westover, K.D. | Deposit date: | 2013-12-31 | Release date: | 2014-07-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.393 Å) | Cite: | Discovery of Type II Inhibitors of TGF beta-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2). J.Med.Chem., 58, 2015
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