7D4G
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7DX4
| The structure of FC08 Fab-hA.CE2-RBD complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Heavy chain of FC08 Fab, ... | Authors: | Cao, L, Wang, X. | Deposit date: | 2021-01-18 | Release date: | 2021-04-21 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2. Natl Sci Rev, 8, 2021
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7EHJ
| human MTHFD2 in complex with compound 21, cofactor and phosphate. | Descriptor: | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ... | Authors: | Lee, L.C, Peng, Y.H, Wu, S.Y. | Deposit date: | 2021-03-29 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2). J.Med.Chem., 64, 2021
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7EHN
| Human MTHFD2 in complex with compound 21 and 9 | Descriptor: | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid, 3-[4-[[1-[(4-chloranyl-1H-indol-2-yl)methyl]-3,7-dimethyl-2,6-bis(oxidanylidene)purin-8-yl]amino]-6-methyl-pyrimidin-2-yl]propanoic acid, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, ... | Authors: | Lee, L.C, Peng, Y.H, Wu, S.Y. | Deposit date: | 2021-03-30 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2). J.Med.Chem., 64, 2021
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7EHM
| Human MTHFD2 in complex with compound 21 and 15 | Descriptor: | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid, (2S)-2-[[4-[[1-[(3,4-dichlorophenyl)methyl]-3,7-dimethyl-2,6-bis(oxidanylidene)purin-8-yl]amino]phenyl]carbonylamino]pentanedioic acid, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, ... | Authors: | Lee, L.C, Peng, Y.H, Wu, S.Y. | Deposit date: | 2021-03-30 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2). J.Med.Chem., 64, 2021
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7EHV
| Human MTHFD2 in complex with compound 21 and 3 | Descriptor: | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid, 1-(3,4-dichlorobenzyl)-8-(((1R,4R)-4-hydroxycyclohexyl)amino)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, ... | Authors: | Lee, L.C, Peng, Y.H, Wu, S.Y. | Deposit date: | 2021-03-30 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2). J.Med.Chem., 64, 2021
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7UR8
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7UR7
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7XTW
| The structure of IsPETase in complex with MHET | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-hydroxyethyloxycarbonyl)benzoic acid, GLYCEROL, ... | Authors: | Yang, Y, Jiang, P.C, Huang, J.-W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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7XTR
| The apo structure of the engineered TfCut | Descriptor: | GLYCEROL, LITHIUM ION, SULFATE ION, ... | Authors: | Yang, Y, Jiang, P.C, Huang, J.-W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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7XTU
| The structure of TfCut S130A | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Yang, Y, Jiang, P.C, Huang, J.-W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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7XTS
| The apo structure of the engineered TfCut S130A | Descriptor: | SODIUM ION, alpha/beta hydrolase | Authors: | Yang, Y, Jiang, P.C, Huang, J.-W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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7XTV
| The structure of MHET-bound TfCut S130A | Descriptor: | 4-(2-hydroxyethyloxycarbonyl)benzoic acid, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yang, Y, Jiang, P.C, Huang, J.-W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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7XTT
| The structure of engineered TfCut S130A in complex with MHET | Descriptor: | 1,2-ETHANEDIOL, 4-(2-hydroxyethyloxycarbonyl)benzoic acid, SODIUM ION, ... | Authors: | Yang, Y, Jiang, P.C, Huang, J.W, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-05-18 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nat Commun, 14, 2023
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2ESE
| Structure of the SAM domain of Vts1p in complex with RNA | Descriptor: | 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*UP*CP*C)-3', Vts1p | Authors: | Allain, F.H.T. | Deposit date: | 2005-10-26 | Release date: | 2006-01-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat.Struct.Mol.Biol., 13, 2006
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2EVZ
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2ES5
| Structure of the SRE RNA | Descriptor: | 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*UP*CP*C)-3' | Authors: | Allain, F.H.T. | Deposit date: | 2005-10-25 | Release date: | 2006-01-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat.Struct.Mol.Biol., 13, 2006
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2ES6
| Structure of the SAM domain of Vts1p | Descriptor: | Vts1p | Authors: | Allain, F.H.T. | Deposit date: | 2005-10-25 | Release date: | 2006-01-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat.Struct.Mol.Biol., 13, 2006
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1JKZ
| NMR Solution Structure of Pisum sativum defensin 1 (Psd1) | Descriptor: | DEFENSE-RELATED PEPTIDE 1 | Authors: | Almeida, M.S, Cabral, K.M.S, Kurtenbach, E, Almeida, F.C.L, Valente, A.P. | Deposit date: | 2001-07-13 | Release date: | 2002-02-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of Pisum sativum defensin 1 by high resolution NMR: plant defensins, identical backbone with different mechanisms of action. J.Mol.Biol., 315, 2002
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1JMO
| Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Baglin, T.P, Carrell, R.W, Esmon, C.T, Huntington, J.A. | Deposit date: | 2001-07-19 | Release date: | 2002-08-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99, 2002
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1JWW
| NMR characterization of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis | Descriptor: | Potential copper-transporting ATPase | Authors: | Banci, L, Bertini, I, Ciofi-Baffoni, S, D'Onofrio, M, Gonnelli, L, Marhuenda-Egea, F, Ruiz-Duenas, F.J. | Deposit date: | 2001-09-05 | Release date: | 2002-04-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis in the apo and Cu(I) loaded states. J.Mol.Biol., 317, 2002
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3DGD
| Crystal structure of the F87M/L110M mutant of human transthyretin at pH 4.6 | Descriptor: | ACETATE ION, GLYCEROL, Transthyretin, ... | Authors: | Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R. | Deposit date: | 2008-06-13 | Release date: | 2008-07-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.383 Å) | Cite: | Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition. J.Biol.Chem., 285, 2010
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3DID
| Crystal structure of the F87M/L110M mutant of human transthyretin at pH 4.6 soaked | Descriptor: | ACETATE ION, GLYCEROL, Transthyretin, ... | Authors: | Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R. | Deposit date: | 2008-06-20 | Release date: | 2008-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition. J.Biol.Chem., 285, 2010
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3EIX
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3EIW
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