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1BXL
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BU of 1bxl by Molmil
STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: BAK PEPTIDE, BCL-XL
著者Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
登録日1996-10-16
公開日1997-10-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
分子名称: Nucleolysin TIA-1 isoform p40
著者Sattler, M, Wang, I.
登録日2014-01-13
公開日2014-04-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
1D8B
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BU of 1d8b by Molmil
NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE
分子名称: SGS1 RECQ HELICASE
著者Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M.
登録日1999-10-21
公開日2000-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
6R8G
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BU of 6r8g by Molmil
Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine
分子名称: 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M.
登録日2019-04-01
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Fragment-Based Approach Identifies an Allosteric Pocket that Impacts Malate Dehydrogenase Activity
Commun Biol, 2021
1KKS
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BU of 1kks by Molmil
Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression
分子名称: 5'-R(*GP*GP*AP*AP*GP*GP*CP*CP*CP*UP*UP*UP*UP*CP*AP*GP*GP*GP*CP*CP*AP*CP*CP*C)-3'
著者Zanier, K, Luyten, I, Crombie, C, Muller, B, Schuemperli, D, Linge, J.P, Nilges, M, Sattler, M.
登録日2001-12-10
公開日2002-03-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.
RNA, 8, 2002
2PEH
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BU of 2peh by Molmil
Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5
分子名称: Splicing factor 3B subunit 1, Splicing factor 45
著者Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
登録日2007-04-03
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
4UQT
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BU of 4uqt by Molmil
RRM-peptide structure in RES complex
分子名称: PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3
著者Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M.
登録日2014-06-25
公開日2014-09-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex.
J.Biol.Chem., 289, 2014
8Q8J
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BU of 8q8j by Molmil
Crystal structure of human GPX4-R152H
分子名称: Glutathione peroxidase
著者Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G.
登録日2023-08-18
公開日2024-08-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human GPX4-R152H
To Be Published
8Q8N
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BU of 8q8n by Molmil
Crystal structure of human GPX4-U46C-I129S-L130S
分子名称: Phospholipid hydroperoxide glutathione peroxidase
著者Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G.
登録日2023-08-18
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
7NDX
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BU of 7ndx by Molmil
Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC
分子名称: 1,2-ETHANEDIOL, DnaJ homolog subfamily B member 1, Nuclear migration protein nudC
著者Delhommel, F, Zak, K.M, Popowicz, G.M, Sattler, M.
登録日2021-02-02
公開日2022-01-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.541 Å)
主引用文献NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Mol.Cell, 82, 2022
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
著者Kachariya, N, Sattler, M, Keil, P, Strasser, K.
登録日2022-10-04
公開日2022-11-09
最終更新日2024-06-19
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
2PE8
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BU of 2pe8 by Molmil
Crystal structure of the UHM domain of human SPF45 (free form)
分子名称: Splicing factor 45
著者Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
登録日2007-04-02
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
3NBZ
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BU of 3nbz by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I)
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
登録日2010-06-04
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
登録日2010-06-04
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3DXB
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BU of 3dxb by Molmil
Structure of the UHM domain of Puf60 fused to thioredoxin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM)
著者Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M.
登録日2008-07-24
公開日2008-10-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
8POI
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BU of 8poi by Molmil
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
分子名称: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30
著者Borggraefe, J, Gaussmann, S, Sattler, M.
登録日2023-07-04
公開日2023-08-23
最終更新日2023-08-30
実験手法SOLUTION NMR
主引用文献Pharmacological perturbation of the phase-separating protein SMNDC1.
Nat Commun, 14, 2023
9GAG
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BU of 9gag by Molmil
Human PEX5 TPR domain in complex with PEX14 KIPSWQIPV peptide
分子名称: Peroxisomal membrane protein PEX14, Peroxisomal targeting signal 1 receptor
著者Emmanouilidis, L, Gaussmann, S, Sattler, M.
登録日2024-07-27
公開日2024-09-11
実験手法SOLUTION NMR
主引用文献Humain complexn PEX5 TPR domain with PEX14 KIPSWQIPV peptide
To Be Published
4EL6
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BU of 4el6 by Molmil
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
分子名称: IL-4-inducing protein
著者Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J.
登録日2012-04-10
公開日2013-04-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
分子名称: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
著者Hipp, C, Sattler, M.
登録日2023-05-14
公開日2023-07-26
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
8PXX
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BU of 8pxx by Molmil
Structure of the WW domain tandem of PRPF40A in complex with SF1
分子名称: Pre-mRNA-processing factor 40 homolog A, Splicing factor 1
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
8PXW
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BU of 8pxw by Molmil
Structure of the WW domain tandem of PRPF40A
分子名称: Pre-mRNA-processing factor 40 homolog A
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
著者Kooshapur, H, Sattler, M.
登録日2018-05-07
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018

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