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6R7E
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BU of 6r7e by Molmil
N-terminally reversed variant of FimA E. coli with alanine insertion at position 20
分子名称: FimA, SULFATE ION
著者Zyla, D, Echeverria, B, Glockshuber, R.
登録日2019-03-28
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA.
J.Biol.Chem., 295, 2020
6S09
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BU of 6s09 by Molmil
C-terminally extended and N-terminally truncated variant of FimA E. coli at 1.5 Angstrom resolution
分子名称: ACETIC ACID, FimA, SODIUM ION, ...
著者Zyla, D, Echeverria, B, Glockshuber, R.
登録日2019-06-14
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA.
J.Biol.Chem., 295, 2020
6R74
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BU of 6r74 by Molmil
N-terminally reversed variant of FimA E. coli
分子名称: SULFATE ION, Type-1 fimbrial protein, A chain
著者Zyla, D, Echeverria, B, Glockshuber, R.
登録日2019-03-28
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA.
J.Biol.Chem., 295, 2020
7U9G
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BU of 7u9g by Molmil
Rabies virus glycoprotein pre-fusion trimer in complex with neutralizing antibody RVA122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, RVA122 Fab Heavy Chain, ...
著者Callaway, H.M, Zyla, D, Larrous, F, Dias de Melo, G, Hastie, K.M, Avalos, R.D, Agarwal, A, Bouhry, H, Corti, D, Saphire, E.O.
登録日2022-03-10
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Sci Adv, 8, 2022
6YEV
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BU of 6yev by Molmil
Crystal structure of MsrA C206 and Trx C35S complex from Escherichia coli
分子名称: Peptide methionine sulfoxide reductase MsrA, SODIUM ION, Thioredoxin 1
著者Napolitano, S, Zyla, D, Glockshuber, R.
登録日2020-03-25
公開日2021-04-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Structure of a complex between the single-cysteine mutant MsrA C206 and Trx C35S from Escherichia coli
To Be Published
6SYM
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BU of 6sym by Molmil
Crystal structure of Escherichia coli MsrB (reduced form)
分子名称: Peptide methionine sulfoxide reductase MsrB, ZINC ION
著者Napolitano, S, Zyla, D, Glockshuber, R.
登録日2019-09-30
公開日2020-10-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6302 Å)
主引用文献Structure of Peptide methionine sulfoxide reductase MsrB at 1.63 Angstrom resolution
To Be Published
5LP9
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BU of 5lp9 by Molmil
FimA wt from S. flexneri
分子名称: Major type 1 subunit fimbrin (Pilin)
著者Zyla, D, Capitani, G, Prota, A, Glockshuber, R.
登録日2016-08-12
公開日2017-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.88626635 Å)
主引用文献Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 2019
8PTU
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BU of 8ptu by Molmil
2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod
分子名称: Type-1 fimbrial protein, A chain
著者Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G.
登録日2023-07-14
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
8UUP
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BU of 8uup by Molmil
Structure of the Measles virus Fusion protein in the pre-fusion conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
著者Zyla, D, Saphire, E.O.
登録日2023-11-01
公開日2024-07-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
8UT2
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BU of 8ut2 by Molmil
Pre-fusion Measles virus fusion protein complexed with Fab 77
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zyla, D, Saphire, E.O.
登録日2023-10-30
公開日2024-07-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
8UTF
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BU of 8utf by Molmil
Structure of the Measles virus Fusion protein in the post-fusion conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Zyla, D, Saphire, E.O.
登録日2023-10-31
公開日2024-07-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
8UUQ
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BU of 8uuq by Molmil
Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, [FIP-HRC]2-PEG11, ...
著者Zyla, D, Saphire, E.O.
登録日2023-11-01
公開日2024-07-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
9AT8
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BU of 9at8 by Molmil
Fab 77-stabilized MeV F ectodomain fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ...
著者Zyla, D, Saphire, E.O.
登録日2024-02-26
公開日2024-07-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
5NKT
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BU of 5nkt by Molmil
FimA wt from E. coli
分子名称: SULFATE ION, Type-1 fimbrial protein, A chain
著者Zyla, D, Capitani, G, Prota, A, Glockshuber, R.
登録日2017-04-03
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 2019
6Y7S
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BU of 6y7s by Molmil
2.85 A cryo-EM structure of the in vivo assembled type 1 pilus rod
分子名称: Type-1 fimbrial protein, A chain
著者Zyla, D, Hospenthal, M, Waksman, G, Glockshuber, R.
登録日2020-03-02
公開日2021-03-31
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
6X84
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BU of 6x84 by Molmil
Sn-glycerol-3-phosphate binding periplasmic protein UgpB from Escherichia coli - W169S, W172S
分子名称: GLYCEROL, sn-glycerol-3-phosphate-binding periplasmic protein UgpB
著者Wu, K, Zyla, D, Bardwell, J.C.A.
登録日2020-06-01
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A metabolite binding protein moonlights as a bile-responsive chaperone.
Embo J., 39, 2020
8PSV
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BU of 8psv by Molmil
2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod
分子名称: Type-1 fimbrial protein, A chain
著者Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G.
登録日2023-07-13
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
6ZS5
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BU of 6zs5 by Molmil
3.5 A cryo-EM structure of human uromodulin filament core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R.
登録日2020-07-15
公開日2020-09-02
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism.
Elife, 9, 2020
6ZYA
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BU of 6zya by Molmil
Extended human uromodulin filament core at 3.5 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R.
登録日2020-07-31
公開日2020-09-02
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism.
Elife, 9, 2020
8F0G
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BU of 8f0g by Molmil
Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1C3 Fab Heavy Chain, ...
著者Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O.
登録日2022-11-02
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
8F0H
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BU of 8f0h by Molmil
Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 1H2 heavy chain, Antibody Fab 1H2 light chain, ...
著者Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O.
登録日2022-11-02
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
7UOV
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BU of 7uov by Molmil
Native Lassa glycoprotein in complex with neutralizing antibodies 12.1F and 37.2D
分子名称: 12.1F heavy chain (variable domain), 12.1F light chain (variable domain), 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Li, H, Saphire, E.O.
登録日2022-04-14
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus.
Sci Transl Med, 14, 2022
7UOT
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BU of 7uot by Molmil
Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 37.2D heavy chain (variable domain), ...
著者Li, H, Saphire, E.O.
登録日2022-04-13
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus.
Sci Transl Med, 14, 2022
5OH0
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BU of 5oh0 by Molmil
The Cryo-Electron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod
分子名称: Type-1 fimbrial protein, A chain
著者Hospenthal, M.K, Costa, T.R.D, Redzej, A, Waksman, G.
登録日2017-07-13
公開日2017-11-22
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod.
Structure, 25, 2017

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件を2024-07-24に公開中

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