4WCE
 
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | | 登録日 | 2014-09-04 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.526 Å) | | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4U67
 | | Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 | | 分子名称: | 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | | 登録日 | 2014-07-28 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
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7A0S
 | | 50S Deinococcus radiodurans ribosome bounded with mycinamicin I | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2020-08-10 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
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7A0R
 | | 50S Deinococcus radiodurans ribosome bounded with mycinamicin I | | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ... | | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2020-08-10 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
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7A18
 | | 50S Deinococcus radiodurans ribosome bounded with mycinamicin IV | | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ... | | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2020-08-12 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
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7PWG
 | | Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution | | 分子名称: | 60S ribosomal protein L13, 60S ribosomal protein L18a, 60S ribosomal protein L27, ... | | 著者 | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | | 登録日 | 2021-10-06 | | 公開日 | 2022-04-20 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
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7PWO
 | | Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution | | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ... | | 著者 | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | | 登録日 | 2021-10-07 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
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7PWF
 | | Cryo-EM structure of small subunit of Giardia lamblia ribosome at 2.9 A resolution | | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | 著者 | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | | 登録日 | 2021-10-06 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
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5NGM
 | | 2.9S structure of the 70S ribosome composing the S. aureus 100S complex | | 分子名称: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Amunts, A, Yonath, A. | | 登録日 | 2017-03-18 | | 公開日 | 2017-10-04 | | 最終更新日 | 2018-11-28 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
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6FXC
 | | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Kidmose, R, Amunts, A, Yonath, A. | | 登録日 | 2018-03-08 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-11-21 | | 実験手法 | ELECTRON MICROSCOPY (6.76 Å) | | 主引用文献 | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
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6AZ1
 | | Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin | | 分子名称: | E-site tRNA, LACK1, MAGNESIUM ION, ... | | 著者 | Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. | | 登録日 | 2017-09-09 | | 公開日 | 2017-12-06 | | 最終更新日 | 2019-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
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6AZ3
 | | Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin | | 分子名称: | 60S ribosomal protein L10, putative, 60S ribosomal protein L11 (L5, ... | | 著者 | Shalev-Benami, M, Zhang, Y, Rozenberg, H, Nobe, Y, Taoka, M, Matzov, D, Zimmerman, E, Bashan, A, Isobe, T, Jaffe, C.L, Yonath, A, Skiniotis, G. | | 登録日 | 2017-09-09 | | 公開日 | 2017-12-06 | | 最終更新日 | 2022-04-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
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5NRG
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M. | | 登録日 | 2017-04-23 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.442 Å) | | 主引用文献 | Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
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6SPB
 | | Pseudomonas aeruginosa 50s ribosome from a clinical isolate with a mutation in uL6 | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. | | 登録日 | 2019-09-01 | | 公開日 | 2019-10-16 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6SPC
 | | Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate | | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. | | 登録日 | 2019-09-01 | | 公開日 | 2019-10-16 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5HKV
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23s ribosomal RNA, 50S ribosomal protein L13, ... | | 著者 | Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M. | | 登録日 | 2016-01-14 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.66 Å) | | 主引用文献 | Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
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5HL7
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2016-01-14 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
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5TCU
 | | Methicillin sensitive Staphylococcus aureus 70S ribosome | | 分子名称: | 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... | | 著者 | Eyal, Z, Ahmed, T, Belousoff, N, Mishra, S, Matzov, D, Bashan, A, Zimmerman, E, Lithgow, T, Bhushan, S, Yonath, A. | | 登録日 | 2016-09-15 | | 公開日 | 2017-05-24 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
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5JVG
 | | The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ... | | 著者 | Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2016-05-11 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.428 Å) | | 主引用文献 | Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3M99
 | | Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module | | 分子名称: | Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... | | 著者 | Kohler, A, Zimmerman, E, Schneider, M, Hurt, E, Zheng, N. | | 登録日 | 2010-03-21 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module.
Cell(Cambridge,Mass.), 141, 2010
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3PIP
 | | Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit | | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Kinashi, H, Rozenberg, H, Yonath, A. | | 登録日 | 2010-11-07 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PIO
 | | Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit | | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Arakawa, K, Kinashi, H, Rozenberg, H, Yonath, A. | | 登録日 | 2010-11-07 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.2473 Å) | | 主引用文献 | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6HMA
 | | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Eyal, Z, Cimicata, G, Matzov, D, Fox, T, de Val, N, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2018-09-12 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit
To Be Published
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6S12
 | | Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22). | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | | 登録日 | 2019-06-18 | | 公開日 | 2019-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
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6S0X
 | | Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | | 登録日 | 2019-06-18 | | 公開日 | 2019-08-21 | | 実験手法 | ELECTRON MICROSCOPY (2.425 Å) | | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
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