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2A4J
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BU of 2a4j by Molmil
Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein
分子名称: 17-mer peptide P1-XPC from DNA-repair protein complementing XP-C cells, Centrin 2
著者Yang, A, Miron, S, Mouawad, L, Duchambon, P, Blouquit, Y, Craescu, C.T.
登録日2005-06-29
公開日2005-07-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein (XPC) from nuclear excision repair.
Biochemistry, 45, 2006
1ZMZ
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BU of 1zmz by Molmil
Solution structure of the N-terminal domain (M1-S98) of human centrin 2
分子名称: Centrin-2
著者Yang, A, Miron, S, Duchambon, P, Assairi, L, Blouquit, Y, Craescu, C.T.
登録日2005-05-11
公開日2006-04-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The N-terminal domain of human centrin 2 has a closed structure, binds calcium with a very low affinity, and plays a role in the protein self-assembly
Biochemistry, 45, 2006
2K7L
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BU of 2k7l by Molmil
NMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1
分子名称: General transcription factor IIF subunit 1, centFCP1-T584PO4 peptide
著者Yang, A, Abbott, K.L, Desjardins, A, Di Lello, P, Omichinski, J.G, Legault, P.
登録日2008-08-13
公開日2009-06-02
最終更新日2020-02-19
実験手法SOLUTION NMR
主引用文献NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase
Biochemistry, 48, 2009
8DA3
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BU of 8da3 by Molmil
Coevolved affibody-Z domain pair LL1.c1
分子名称: Affibody LL1.FILF, Immunoglobulin G-binding protein A, MALONATE ION, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA4
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BU of 8da4 by Molmil
Coevolved affibody-Z domain pair LL1.c2
分子名称: Affibody LL1.FIVM, Immunoglobulin G-binding protein A, SULFATE ION, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA9
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BU of 8da9 by Molmil
Coevolved affibody-Z domain pair LL2.c3
分子名称: Affibody LL2.FIIV, GLYCEROL, Immunoglobulin G-binding protein A, ...
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA6
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BU of 8da6 by Molmil
Coevolved affibody-Z domain pair LL1.c5
分子名称: Affibody LL1.FIIM, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA5
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BU of 8da5 by Molmil
Coevolved affibody-Z domain pair LL1.c4
分子名称: GLYCEROL, Immunoglobulin G-binding protein A, affibody LL1.FIVM
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA8
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BU of 8da8 by Molmil
Coevolved affibody-Z domain pair LL2.c1
分子名称: Affibody LL2.FIIK, GLYCEROL, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DA7
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BU of 8da7 by Molmil
Coevolved affibody-Z domain pair LL1.c6
分子名称: Immunoglobulin G-binding protein A, MALONATE ION, affibody LL1.FIFV
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DAC
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BU of 8dac by Molmil
Coevolved affibody-Z domain pair LL2.c22
分子名称: Affibody LL2.FILV, GLYCEROL, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DAA
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BU of 8daa by Molmil
Coevolved affibody-Z domain pair LL2.c7
分子名称: Affibody LL2.FIVK, Immunoglobulin G-binding protein A, MALONATE ION
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8DAB
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BU of 8dab by Molmil
Coevolved affibody-Z domain pair LL2.c17
分子名称: Affibody LL2.IVVY, Immunoglobulin G-binding protein A
著者Jude, K.M, Yang, A, Garcia, K.C.
登録日2022-06-13
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.134 Å)
主引用文献Deploying synthetic coevolution and machine learning to engineer protein-protein interactions.
Science, 381, 2023
8HFC
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BU of 8hfc by Molmil
Cryo-EM structure of yeast Erf2/Erf4 complex
分子名称: PALMITIC ACID, Palmitoyltransferase ERF2, Ras modification protein ERF4, ...
著者Wu, J, Hu, Q, Zhang, Y, Yang, A, Liu, S.
登録日2022-11-10
公開日2023-11-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation.
Nat.Struct.Mol.Biol., 31, 2024
8HF3
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BU of 8hf3 by Molmil
Cryo-EM structure of human ZDHHC9/GCP16 complex
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, Golgin subfamily A member 7, PALMITIC ACID, ...
著者Wu, J, Hu, Q, Zhang, Y, Liu, S, Yang, A.
登録日2022-11-09
公開日2023-11-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation.
Nat.Struct.Mol.Biol., 31, 2024
4APP
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BU of 4app by Molmil
Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide
分子名称: GLYCEROL, N-[6,6-dimethyl-5-[(2S)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PAK 4
著者Knighton, D.D, Deng, Y.L, Wang, C, Guo, C, McAlpine, I, Zhang, J, Kephart, S, Johnson, M.C, Li, H, Bouzida, D, Yang, A, Dong, L, Marakovits, J, Tikhe, J, Richardson, P, Guo, L.C, Kania, R, Edwards, M.P, Kraynov, E, Christensen, J, Piraino, J, Lee, J, Dagostino, E, Del-Carmen, C, Smeal, T, Murray, B.W.
登録日2012-04-04
公開日2012-06-06
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Pyrroloaminopyrazoles as Novel Pak Inhibitors.
J.Med.Chem., 55, 2012
8HVS
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BU of 8hvs by Molmil
Solution Structure of the Antimicrobial Peptide HT-2
分子名称: ARG-PHE-LEU-ARG-ARG-ILE-PHE-PHE-PHE-PHE
著者Li, S, Yang, A.
登録日2022-12-27
公開日2023-10-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Design and evaluation of tadpole-like conformational antimicrobial peptides.
Commun Biol, 6, 2023
3LD1
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BU of 3ld1 by Molmil
Crystal Structure of IBV Nsp2a
分子名称: Replicase polyprotein 1a
著者Xu, Y, Cong, L, Wei, L, Fu, J, Chen, C, Yang, A, Tang, H, Bartlam, M, Rao, Z.
登録日2010-01-12
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献IBV nsp2 is an endosome-associated protein and viral pathogenicity factor
To be Published
7LH9
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BU of 7lh9 by Molmil
Crystal structure of BRPF2 PWWP domain in complex with DNA
分子名称: Bromodomain-containing protein 1, DNA
著者Zhang, M, Lei, M, Qin, S, Dong, A, Yang, A, Li, Y, Loppnau, P, Hughes, T.R, Arrowsmith, C.H, Edwards, A.M, Min, J, Liu, J, Structural Genomics Consortium (SGC)
登録日2021-01-21
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.
Biochim Biophys Acta Gene Regul Mech, 1864, 2021
5MS7
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BU of 5ms7 by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ_20-502
分子名称: BARIUM ION, GLYCEROL, Legionella pneumophila effector protein RavZ
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS2
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BU of 5ms2 by Molmil
Crystal structure of the Legionella pneumophila effector protein RavZ in complex with human LC3B
分子名称: Legionella pneumophila effector protein RavZ, Microtubule-associated proteins 1A/1B light chain 3B
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-30
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS5
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BU of 5ms5 by Molmil
Low-salt structure of RavZ LIR2-fused human LC3B
分子名称: GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS8
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BU of 5ms8 by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ_1-487
分子名称: BARIUM ION, DI(HYDROXYETHYL)ETHER, Legionella pneumophila effector protein RavZ
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS6
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BU of 5ms6 by Molmil
High-salt structure of RavZ LIR2-fused human LC3B
分子名称: Microtubule-associated proteins 1A/1B light chain 3B
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
7S5B
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BU of 7s5b by Molmil
Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
分子名称: Miniprotein Binder
著者Walsh, S.T.R, Cao, L, Baker, D.
登録日2021-09-10
公開日2022-05-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022

 

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