4XHU
| |
4XHT
| |
4XHW
| |
4MQV
| Crystal complex of Rpa32c and Smarcal1 N-terminus | 分子名称: | Replication protein A 32 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | 著者 | Xie, S, Qian, C.M. | 登録日 | 2013-09-16 | 公開日 | 2014-07-02 | 最終更新日 | 2014-12-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins Febs J., 281, 2014
|
|
3T6R
| Structure of UHRF1 in complex with unmodified H3 N-terminal tail | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3.1t N-terminal peptide, MAGNESIUM ION, ... | 著者 | Xie, S, Jakoncic, J, Qian, C.M. | 登録日 | 2011-07-29 | 公開日 | 2011-11-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail J.Mol.Biol., 415, 2012
|
|
4ZDT
| Crystal structure of the RING finger domain of Slx1 in complex with the C-terminal domain of Slx4 | 分子名称: | GLYCEROL, SULFATE ION, Structure-specific endonuclease subunit slx1, ... | 著者 | Lian, F.M, Xie, S, Qian, C.M. | 登録日 | 2015-04-19 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and SUMO binding of Slx1-Slx4 complex Sci Rep, 6, 2016
|
|
4GXO
| Crystal structure of Staphylococcus aureus protein SarZ mutant C13E | 分子名称: | GLYCEROL, MarR family regulatory protein | 著者 | Sun, F, Ding, Y, Ji, Q, Liang, Z, Deng, X, Wong, C.C, Yi, C, Zhang, L, Xie, S, Alvarez, S, Hicks, L.M, Luo, C, Jiang, H, Lan, L, He, C. | 登録日 | 2012-09-04 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6JXR
| Structure of human T cell receptor-CD3 complex | 分子名称: | T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, T-cell surface glycoprotein CD3 delta chain, ... | 著者 | Dong, D, Zheng, L, Lin, J, Zhu, Y, Li, N, Zhang, B, Xie, S, Zheng, J, Wang, Y, Gao, N, Huang, Z. | 登録日 | 2019-04-24 | 公開日 | 2019-09-11 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of assembly of the human T cell receptor-CD3 complex. Nature, 573, 2019
|
|
8YLC
| The crystal structure of PDE4D with Amentoflavone | 分子名称: | 3',5'-cyclic-AMP phosphodiesterase 4D, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ... | 著者 | Huang, Y.-Y, Luo, H.-B. | 登録日 | 2024-03-06 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.30003715 Å) | 主引用文献 | Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects Chin.Chem.Lett., 2024
|
|
5WYM
| Crystal structure of an anti-connexin26 scFv | 分子名称: | anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain | 著者 | Li, S, Xu, L. | 登録日 | 2017-01-13 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders Front Mol Neurosci, 10, 2017
|
|
8JKZ
| |
8JL0
| Cryo-EM structure of the prokaryotic SPARSA system complex | 分子名称: | DNA (5'-D(P*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*T)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain protein, ... | 著者 | Xu, X, Zhen, X, Long, F. | 登録日 | 2023-06-02 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system. Nat Commun, 15, 2024
|
|
5Z65
| Crystal structure of porcine aminopeptidase N ectodomain in functional form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sun, Y.G, Li, R, Jiang, L.G, Qiao, S.L, Zhang, G.P. | 登録日 | 2018-01-22 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Characterization of the interaction between recombinant porcine aminopeptidase N and spike glycoprotein of porcine epidemic diarrhea virus. Int. J. Biol. Macromol., 117, 2018
|
|
2M6X
| |
5TBM
| Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex | 分子名称: | 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | 著者 | Du, X. | 登録日 | 2016-09-12 | 公開日 | 2016-09-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Cancer Res., 76, 2016
|
|
8T1R
| Crystal structure of human CPSF73 catalytic segment in complex with compound 2 | 分子名称: | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(3-methoxyphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ... | 著者 | Huang, J, Tong, L. | 登録日 | 2023-06-02 | 公開日 | 2023-11-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol, 31, 2024
|
|
8T1Q
| Crystal structure of human CPSF73 catalytic segment in complex with compound 1 | 分子名称: | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ... | 著者 | Huang, J, Tong, L. | 登録日 | 2023-06-02 | 公開日 | 2023-11-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol, 31, 2024
|
|
4OUS
| |
4OUL
| |
4O60
| |
4OUM
| |
4QFV
| |
5YDR
| Structure of DNMT1 RFTS domain in complex with ubiquitin | 分子名称: | DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ... | 著者 | Qian, C. | 登録日 | 2017-09-14 | 公開日 | 2018-02-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res., 46, 2018
|
|
5GJK
| |
8HMH
| The closed state of RGLG2-VWA | 分子名称: | E3 ubiquitin-protein ligase RGLG2, MAGNESIUM ION | 著者 | Wang, Q. | 登録日 | 2022-12-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | The regulation of RGLG2-VWA by Ca 2+ ions. Biochim Biophys Acta Proteins Proteom, 1872, 2024
|
|