8JL0

Cryo-EM structure of the prokaryotic SPARSA system complex

Summary for 8JL0

• Entry DOI: 10.2210/pdb8jl0/pdb
• Related: 8JKZ
• EMDB information: 36385
• Descriptor: Sir2 superfamily protein, Piwi domain protein, DNA (5'-D(P*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*T)-3'), ... (5 entities in total)
• Functional Keywords: the sparsa antiviral system, nadase, argonaute protein, antiviral protein, antiviral protein-dna-rna complex, antiviral protein/dna/rna
• Biological source: Geobacter sulfurreducens; More
• Total number of polymer chains: 4
• Total formula weight: 134204.25

Authors

Xu, X.,Zhen, X.,Long, F. (deposition date: 2023-06-02, release date: 2024-01-24)

• Primary citation: Zhen, X.,Xu, X.,Ye, L.,Xie, S.,Huang, Z.,Yang, S.,Wang, Y.,Li, J.,Long, F.,Ouyang, S.; Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system.; Nat Commun, 15:450-450, 2024; PubMed: 38200015; DOI: 10.1038/s41467-023-44660-7

Experimental method

ELECTRON MICROSCOPY (3.1 Å)