5JDE
 
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5JDD
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5JDJ
 | | Crystal structure of domain I10 from titin in space group P212121 | | 分子名称: | CALCIUM ION, Titin | | 著者 | Williams, R, Bogomolovas, J, Labiet, S, Mayans, O. | | 登録日 | 2016-04-16 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.738 Å) | | 主引用文献 | Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.
Open Biology, 6, 2016
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2G50
 | | The location of the allosteric amino acid binding site of muscle pyruvate kinase. | | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ALANINE, ... | | 著者 | Holyoak, T, Williams, R, Fenton, A.W. | | 登録日 | 2006-02-22 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase.
Biochemistry, 45, 2006
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2PT7
 | | Crystal structure of Cag VirB11 (HP0525) and an inhibitory protein (HP1451) | | 分子名称: | Cag-alfa, Hypothetical protein | | 著者 | Hare, S, Fischer, W, Williams, R, Terradot, L, Bayliss, R, Haas, R, Waksman, G. | | 登録日 | 2007-05-08 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase.
Embo J., 26, 2007
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8BVO
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8BXR
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1RBJ
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4AG6
 | | Structure of VirB4 of Thermoanaerobacter pseudethanolicus | | 分子名称: | SULFATE ION, TYPE IV SECRETORY PATHWAY VIRB4 COMPONENTS-LIKE PROTEIN | | 著者 | Wallden, K, Williams, R, Yan, J, Lian, P.W, Wang, L, Thalassinos, K, Orlova, E.V, Waksman, G. | | 登録日 | 2012-01-24 | | 公開日 | 2012-07-04 | | 最終更新日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of the Virb4 ATPase, Alone and Bound to the Core Complex of a Type Iv Secretion System.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4AG5
 | | Structure of VirB4 of Thermoanaerobacter pseudethanolicus | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Wallden, K, Williams, R, Yan, J, Lian, P.W, Wang, L, Thalassinos, K, Orlova, E.V, Waksman, G. | | 登録日 | 2012-01-24 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the Virb4 ATPase, Alone and Bound to the Core Complex of a Type Iv Secretion System.
Proc.Natl.Acad.Sci.USA, 109, 2012
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8EB9
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8EBB
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8BW6
 | | Titin FnIII-domain I110 (I/A6) from the MIR region | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Mayans, O, Fleming, J.R. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
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7T69
 | | Crystal structure of Avr3 (SIX1) from Fusarium oxysporum f. sp. lycopersici | | 分子名称: | Avr3 (SIX1), Secreted in xylem 1, SULFATE ION | | 著者 | Yu, D.S, Outram, M.A, Ericsson, D.J, Jones, D.A, Williams, S.J. | | 登録日 | 2021-12-13 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Elife, 2023
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7T6A
 | | Crystal structure of Avr1 (SIX4) from Fusarium oxysporum f. sp. lycopersici | | 分子名称: | Avr1 (FolSIX4), Avirulence protein 1, Avr1 (SIX4), ... | | 著者 | Yu, D.S, Outram, M.A, Ericsson, D.J, Jones, D.A, Williams, S.J. | | 登録日 | 2021-12-13 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Elife, 2023
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5NGB
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4QEG
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2AJL
 | | X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor | | 分子名称: | 1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 | | 著者 | Qiao, L, Baumann, C.A, Crysler, C.S, Ninan, N.S, Abad, M.C, Spurlino, J.C, DesJarlais, R.L, Kervinen, J, Neeper, M.P, Bayoumy, S.S. | | 登録日 | 2005-08-02 | | 公開日 | 2005-11-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
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5UE3
 | | proMMP-9desFnII | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Matrix metalloproteinase-9, ... | | 著者 | Alexander, R.S, Spurlino, J, Milligan, C. | | 登録日 | 2016-12-29 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
J. Biol. Chem., 292, 2017
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5UE4
 | | proMMP-9desFnII complexed to JNJ0966 INHIBITOR | | 分子名称: | CALCIUM ION, Matrix metalloproteinase-9, SULFATE ION, ... | | 著者 | Alexander, R.S, Spurlino, J, Milligan, C. | | 登録日 | 2016-12-29 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
J. Biol. Chem., 292, 2017
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5TVZ
 | | Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820 | | 分子名称: | Nucleoporin POM152 | | 著者 | Dutta, K, Sampathkumar, P, Cowburn, D, Almo, S.C, Rout, M.P, Fernandez-Martinez, J. | | 登録日 | 2016-11-10 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure, 25, 2017
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8F2G
 | | Crystal structure of Hen Egg White Lysozyme at 0.44 GPa | | 分子名称: | Lysozyme C | | 著者 | Marshall, A.C, Boer, S.A, Turner, G, Moggach, S.A, Bond, C.S, Vrielink, A. | | 登録日 | 2022-11-08 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | High-pressure single-crystal diffraction at the Australian Synchrotron.
J.Synchrotron Radiat., 30, 2023
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7SUT
 | | Light harvesting phycobiliprotein HaPE645 from the cryptophyte Hemiselmis andersenii CCMP644 | | 分子名称: | (15,16)-DIHYDROBILIVERDIN (SINGLY LINKED), 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Rathbone, H.W, Michie, K.A, Laos, A.L, Curmi, P.M.G. | | 登録日 | 2021-11-18 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii.
Commun Biol, 6, 2023
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5V61
 | | Phospho-ERK2 bound to bivalent inhibitor SBP2 | | 分子名称: | 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid, 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, ... | | 著者 | Lechtenberg, B.C, Riedl, S.J. | | 登録日 | 2017-03-15 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
ACS Med Chem Lett, 8, 2017
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5V62
 | | Phospho-ERK2 bound to bivalent inhibitor SBP3 | | 分子名称: | 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, Mitogen-activated protein kinase 1, ... | | 著者 | Lechtenberg, B.C, Riedl, S.J. | | 登録日 | 2017-03-15 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
ACS Med Chem Lett, 8, 2017
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