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8HY4
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BU of 8hy4 by Molmil
Crystal structure of human transthyretin variant A97S at pH 7.6
分子名称: Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2023-01-05
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7Y6J
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Crystal structure of human transthyretin variant A97S at pH 5.4
分子名称: GLYCEROL, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-20
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YBR
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Crystal structure of human transthyretin variant A97S complexed with Tolcapone
分子名称: Tolcapone, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-29
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YCQ
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BU of 7ycq by Molmil
Crystal structure of human transthyretin variant A97S complexed with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-07-01
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
6A4X
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Oxidase ChaP-H2
分子名称: Bleomycin resistance protein, FE (II) ION
著者Zhang, B, Wang, Y.S, Ge, H.M.
登録日2018-06-21
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
1ONB
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BU of 1onb by Molmil
Solution structure of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
分子名称: helicase NS3
著者Liu, D, Wang, Y.S, Gesell, J.J, Wyss, D.F.
登録日2003-02-27
公開日2003-03-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
J.Mol.Biol., 314, 2001
1OVQ
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BU of 1ovq by Molmil
Solution structure of the hypothetical protein YqgF from Escherichia coli
分子名称: Hypothetical protein yqgF
著者Liu, D, Wang, Y.S, Wyss, D.F.
登録日2003-03-27
公開日2003-11-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold.
J.Biomol.NMR, 27, 2003
8KE2
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BU of 8ke2 by Molmil
PylRS C-terminus domain mutant bound with L-3-trifluoromethylphenylalanine and AMPNP
分子名称: (2S)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.19639969 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE3
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BU of 8ke3 by Molmil
PylRS C-terminus domain mutant bound with D-3-trifluoromethylphenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89980984 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE5
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PylRS C-terminus domain mutant bound with D-3-chlorophenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-(3-chlorophenyl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.900073 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE6
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PylRS C-terminus domain mutant bound with L-3-chlorophenylalanine and AMPNP
分子名称: 3-CHLORO-L-PHENYLALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89570856 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE1
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BU of 8ke1 by Molmil
PylRS C-terminus domain mutant bound with L-3-bromophenylalanine and AMPNP
分子名称: 3-bromo-L-phenylalanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50081539 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE4
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BU of 8ke4 by Molmil
PylRS C-terminus domain mutant bound with D-3-bromophenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-(3-bromophenyl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75050962 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
6KL6
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BU of 6kl6 by Molmil
Crystal structure of MERS-CoV N-NTD complexed with 5-Benzyloxygramine
分子名称: N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine, Nucleoprotein
著者Hou, M.H, Lin, S.M, Wang, Y.S, Hsu, J.N.
登録日2019-07-29
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
6KL2
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BU of 6kl2 by Molmil
Structure of the N-terminal domain of Middle East respiratory syndrome coronavirus nucleocapsid protein
分子名称: Nucleoprotein
著者Hou, M.H, Wang, Y.S, Lin, S.M, Hsu, J.N.
登録日2019-07-29
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
6LY6
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BU of 6ly6 by Molmil
PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP
分子名称: MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5001328 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LY3
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BU of 6ly3 by Molmil
PylRS C-terminus domain mutant bound with 3-Benzothienyl-L-alanine and AMPNP
分子名称: 3-(1-benzothiophen-3-yl)-L-alanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89590144 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LYA
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BU of 6lya by Molmil
PylRS C-terminus domain mutant bound with 1-Methyl-L-tryptophan and AMPNP
分子名称: 1,2-ETHANEDIOL, 1-Methyl-L-tryptophan, MAGNESIUM ION, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.590702 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LY7
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BU of 6ly7 by Molmil
PylRS C-terminus domain mutant bound with 1-Formyl-L-tryptophan and AMPNP
分子名称: MAGNESIUM ION, N1-FORMYL-TRYPTOPHAN, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.09447265 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LYB
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PylRS C-terminus domain mutant in complex with 3-Benzothienyl-D-alanine and AMPNP
分子名称: (2R)-2-azanyl-3-(1-benzothiophen-3-yl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.90366471 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
1JR6
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BU of 1jr6 by Molmil
Solution Structure of an Engineered Arginine-rich Subdomain 2 of the Hepatitis C Virus NS3 RNA Helicase
分子名称: Helicase NS3
著者Liu, D, Wyss, D.F, Wang, Y.S, Gesell, J.J.
登録日2001-08-10
公開日2002-08-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase.
J.Mol.Biol., 314, 2001
4ZIB
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BU of 4zib by Molmil
Crystal Structure of the C-terminal domain of PylRS mutant bound with 3-benzothienyl-l-alanine and ATP
分子名称: 1,2-ETHANEDIOL, 3-(1-benzothiophen-3-yl)-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Nakamura, A, Guo, L.T, Wang, Y.S, Soll, D.
登録日2015-04-28
公開日2016-03-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Nucleic Acids Res., 43, 2015
1NM3
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BU of 1nm3 by Molmil
Crystal structure of Heamophilus influenza hybrid-Prx5
分子名称: Protein HI0572, SULFATE ION
著者Kim, S.J, Woo, J.R, Hwang, Y.S, Jeong, D.G, Shin, D.H, Kim, K.H, Ryu, S.E.
登録日2003-01-08
公開日2003-03-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Tetrameric Structure of Haemophilus influenza Hybrid Prx5 Reveals Interactions between Electron Donor and Acceptor Proteins.
J.Biol.Chem., 278, 2003
6KL5
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Structure of The N-terminal domain of Middle East respiratory syndrome coronavirus Nucleocapsid Protein complexed with Benzyl 2-(Hydroxymethyl)-1-Indolinecarboxylate
分子名称: (phenylmethyl) (2S)-2-(hydroxymethyl)-2,3-dihydroindole-1-carboxylate, Nucleoprotein
著者Hou, M.H, Lin, S.M, Hsu, J.N, Wang, Y.S.
登録日2019-07-29
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
7W6M
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BU of 7w6m by Molmil
Cryo-EM map of PEDV (Pintung 52) S protein with all three protomers in the D0-down conformation determined in situ on intact viral particles.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2021-12-02
公開日2022-08-03
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022

 

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