6ENH
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6ZY7
| Cryo-EM structure of the entire Human topoisomerase II alpha in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.64 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY6
| Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 2 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY8
| Cryo-EM structure of the entire Human topoisomerase II alpha in State 2 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY5
| Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ENG
| Crystal structure of the 43K ATPase domain of Escherichia coli gyrase B in complex with an aminocoumarin | 分子名称: | CHLORIDE ION, Coumermycin A1, DNA gyrase subunit B, ... | 著者 | Vanden Broeck, A, McEwen, A.G, Lamour, V. | 登録日 | 2017-10-04 | 公開日 | 2019-04-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for DNA Gyrase Interaction with Coumermycin A1. J.Med.Chem., 62, 2019
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6RKW
| CryoEM structure of the complete E. coli DNA Gyrase complex bound to a 130 bp DNA duplex | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA (58-MER), DNA (62-MER), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2019-04-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
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6RKS
| E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 without TOPRIM insertion | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2019-04-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
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6RKV
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6RKU
| E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2019-04-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
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4BZG
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose | 分子名称: | ALDOSE 1-EPIMERASE, CITRIC ACID, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2013-07-25 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose To be Published
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4BZH
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose and trehalose | 分子名称: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL, ... | 著者 | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2013-07-25 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose and Trehalose To be Published
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4BZF
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis with trehalose | 分子名称: | ACETATE ION, ALDOSE 1-EPIMERASE, CITRIC ACID, ... | 著者 | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2013-07-25 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis with Trehalose To be Published
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4BZE
| Crystal structure of galactose mutarotase GalM from Bacillus subtilis | 分子名称: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL | 著者 | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2013-07-25 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis To be Published
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8FL0
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8FKZ
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8FKP
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8FKU
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8FL7
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8FKW
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8FLD
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8FKY
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8FLF
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8FKR
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8FKT
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