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1TG6
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BU of 1tg6 by Molmil
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLYCEROL, ...
著者Kang, S.G, Maurizi, M.R, Thompson, M, Mueser, T, Ahvazi, B.
登録日2004-05-28
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
3ZNR
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BU of 3znr by Molmil
HDAC7 bound with inhibitor TMP269
分子名称: HISTONE DEACETYLASE 7, N-{[4-(4-phenyl-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ...
著者Lobera, m, madauss, k, pohlhaus, d, trump, r, nolan, m.
登録日2013-02-15
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
3ZNS
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BU of 3zns by Molmil
HDAC7 bound with TFMO inhibitor tmp942
分子名称: HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ...
著者Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A.
登録日2013-02-15
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
7ZGJ
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BU of 7zgj by Molmil
Trypanosoma brucei gambiense ISG65 in complex with human complement component C3
分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3, ...
著者Suelzen, H, Zoll, S.
登録日2022-04-03
公開日2023-04-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun, 14, 2023
7ZGK
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BU of 7zgk by Molmil
Trypanosoma brucei gambiense ISG65 in complex with human complement component C3b
分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3 beta chain, ...
著者Suelzen, H, Zoll, S.
登録日2022-04-03
公開日2023-04-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun, 14, 2023
6OB5
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BU of 6ob5 by Molmil
Computationally-designed, modular sense/response system (S3-2D)
分子名称: Ankyrin Repeat Domain (AR), S3-2D variant, FARNESYL DIPHOSPHATE, ...
著者Thompson, M.C, Glasgow, A.A, Huang, Y.M, Fraser, J.S, Kortemme, T.
登録日2019-03-19
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Computational design of a modular protein sense-response system.
Science, 366, 2019
3SW8
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BU of 3sw8 by Molmil
Strep Peptide Deformylase with a time dependent dichlorobenzamide-reverse hydroxamic acid
分子名称: 2,3-dichloro-N-{2-[formyl(hydroxy)amino]ethyl}benzamide, NICKEL (II) ION, Peptide deformylase 3, ...
著者Campobasso, N, Smith, K.J.
登録日2011-07-13
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Biochemistry, 50, 2011
3STR
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BU of 3str by Molmil
Strep Peptide Deformylase with a time dependent thiazolidine hydroxamic acid
分子名称: (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-[2-(hydroxyamino)-2-oxoethyl]-1,3-thiazolidine-4-carboxamide, GLYCEROL, NICKEL (II) ION, ...
著者Campobasso, N, Ward, P.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Biochemistry, 50, 2011
3SVJ
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BU of 3svj by Molmil
Strep Peptide Deformylase with a time dependent thiazolidine amide
分子名称: (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-methyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, NICKEL (II) ION, ...
著者Campobasso, N, Ward, P.
登録日2011-07-12
公開日2011-07-27
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Biochemistry, 50, 2011
6NI8
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BU of 6ni8 by Molmil
Pseudomonas fluorescens isocyanide hydratase rotating anode 298K
分子名称: Isonitrile hydratase InhA
著者Wilson, M.A, Dasgupta, M, van den Bedem, H.
登録日2018-12-26
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Cysteine modification can gate non-equilibrium conformational dynamics during enzyme catalysis
Biorxiv, 2019
5V4L
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BU of 5v4l by Molmil
Cryptococcus neoformans adenylosuccinate lyase
分子名称: Adenylosuccinate lyase
著者Chitty, J, Williams, S.J, Kobe, B, Fraser, J.A.
登録日2017-03-09
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J. Biol. Chem., 292, 2017

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件を2024-07-24に公開中

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