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6HI1
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BU of 6hi1 by Molmil
PI3 Kinase Delta in complex with 3[6(morpholin4yl)pyridin2yl]phenol
分子名称: 3-(6-morpholin-4-ylpyridin-2-yl)phenol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
著者Convery, M.A, Summers, D, Peace, S.
登録日2018-08-29
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines.
To be published
6HI2
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BU of 6hi2 by Molmil
PI3 Kinase Delta in complex with 3{6[(1S,6R)3oxabicyclo[4.1.0]heptan6yl]pyridin2yl}phenol
分子名称: 3-[6-[(1~{S},6~{R})-3-oxabicyclo[4.1.0]heptan-6-yl]pyridin-2-yl]phenol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
著者Convery, M.A, Summers, D, Peace, S.
登録日2018-08-29
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines.
to be published
6HI9
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BU of 6hi9 by Molmil
PI3 Kinase Delta in complex with 3[6(oxan4yl)pyridin2yl]phenol
分子名称: 3-[6-(oxan-4-yl)pyridin-2-yl]phenol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
著者Convery, M.A, Summers, D, Peace, S.
登録日2018-08-29
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines.
To be published
4CS3
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BU of 4cs3 by Molmil
Catalytic domain of Pyrrolysyl-tRNA synthetase mutant Y306A, Y384F in complex with an adenylated furan-bearing noncanonical amino acid and pyrophosphate
分子名称: 1,2-ETHANEDIOL, 2-(furan-2-yl)ethyl hydrogen carbonate, ADENOSINE MONOPHOSPHATE, ...
著者Schmidt, M.J, Weber, A, Pott, M, Welte, W, Summerer, D.
登録日2014-03-04
公開日2014-04-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Structural Basis of Furan-Amino Acid Recognition by a Polyspecific Aminoacyl-tRNA-Synthetase and its Genetic Encoding in Human Cells.
Chembiochem, 15, 2014
4CS4
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BU of 4cs4 by Molmil
Catalytic domain of Pyrrolysyl-tRNA synthetase mutant Y306A, Y384F in complex with AMPPNP
分子名称: 1,2-ETHANEDIOL, 2-{[dihydroxy(4-aminoethylphenyl)-{4}-sulfanyl]amino}-3-hydroxypropanoic acid, MAGNESIUM ION, ...
著者Schmidt, M.J, Weber, A, Pott, M, Welte, W, Summerer, D.
登録日2014-03-04
公開日2014-04-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.349 Å)
主引用文献Structural Basis of Furan-Amino Acid Recognition by a Polyspecific Aminoacyl-tRNA-Synthetase and its Genetic Encoding in Human Cells.
Chembiochem, 15, 2014
4CS2
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BU of 4cs2 by Molmil
Catalytic domain of Pyrrolysyl-tRNA synthetase mutant Y306A, Y384F in its apo form
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRROLYSINE--TRNA LIGASE
著者Schmidt, M.J, Weber, A, Pott, M, Welte, W, Summerer, D.
登録日2014-03-04
公開日2014-04-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Furan-Amino Acid Recognition by a Polyspecific Aminoacyl-tRNA-Synthetase and its Genetic Encoding in Human Cells.
Chembiochem, 15, 2014
8AJR
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BU of 8ajr by Molmil
The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2
分子名称: Methyl-CpG-binding protein 2
著者Singh, H.
登録日2022-07-28
公開日2023-02-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity.
Nucleic Acids Res., 51, 2023
8ALQ
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BU of 8alq by Molmil
The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2 that Binds to Asymmetrically Modified DNA
分子名称: Methyl-CpG-binding protein 2
著者Singh, H.
登録日2022-08-01
公開日2023-02-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity.
Nucleic Acids Res., 51, 2023
5K1X
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BU of 5k1x by Molmil
Catalytic domain of polyspecific pyrrolysyl-tRNA synthetase mutant Y306A/N346A/C348A/Y384F in complex with AMPPNP
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Weber, A.
登録日2016-05-18
公開日2016-10-19
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.
Chem.Commun.(Camb.), 52, 2016
5K1P
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BU of 5k1p by Molmil
Catalytic domain of polyspecific pyrrolysyl-tRNA synthetase mutant N346A/C348A in complex with AMPPNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase
著者Weber, A.
登録日2016-05-18
公開日2016-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.
Chem.Commun.(Camb.), 52, 2016
3D6U
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BU of 3d6u by Molmil
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
分子名称: 4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase
著者Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G.
登録日2008-05-20
公開日2008-05-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
3D6V
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BU of 3d6v by Molmil
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
分子名称: 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase
著者Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G.
登録日2008-05-20
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007

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件を2024-11-06に公開中

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