6HI1

PI3 Kinase Delta in complex with 3[6(morpholin4yl)pyridin2yl]phenol

Summary for 6HI1

• Entry DOI: 10.2210/pdb6hi1/pdb
• Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, 3-(6-morpholin-4-ylpyridin-2-yl)phenol (3 entities in total)
• Functional Keywords: kinase, drug discovery, complex, transferase
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 1
• Total formula weight: 108079.96

Authors

Convery, M.A.,Summers, D.,Peace, S. (deposition date: 2018-08-29, release date: 2019-09-11)

• Primary citation: Convery, M.A.,Summers, D.,Hobbs, H.,Jamieson, C.,Kennedy, A.R.,Pal, S.,Peace, S.,Pogany, P.,Upton, R.; A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines.; To be published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)