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2XXM
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BU of 2xxm by Molmil
Crystal structure of the HIV-1 capsid protein C-terminal domain in complex with a camelid VHH and the CAI peptide.
分子名称: ACETATE ION, CAMELID VHH 9, CAPSID PROTEIN P24, ...
著者Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A.
登録日2010-11-10
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XV6
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BU of 2xv6 by Molmil
Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 220) in complex with a camelid VHH.
分子名称: CAMELID VHH 9, CAPSID PROTEIN P24
著者Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A.
登録日2010-10-22
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XT1
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BU of 2xt1 by Molmil
Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 231) in complex with a camelid VHH.
分子名称: CAMELID VHH 9, GAG POLYPROTEIN, GLYCEROL
著者Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A.
登録日2010-10-03
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XXC
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BU of 2xxc by Molmil
Crystal structure of a camelid VHH raised against the HIV-1 capsid protein C-terminal domain.
分子名称: CAMELID VHH 9
著者Igonet, S, Vaney, M.C, Bartonova, V, Helma, J, Rothbauer, U, Leonhardt, H, Stura, E, Krausslich, H.-G, Rey, F.A.
登録日2010-11-10
公開日2011-10-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2HEO
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BU of 2heo by Molmil
General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
著者Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P.
登録日2006-06-21
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
2AS8
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BU of 2as8 by Molmil
Crystal structure of mature and fully active Der p 1 allergen
分子名称: MAGNESIUM ION, Major mite fecal allergen Der p 1
著者de Halleux, S, Stura, E, VanderElst, L, Carlier, V, Jacquemin, M, Saint-Remy, J.-M.
登録日2005-08-23
公開日2005-12-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen
J.Allergy Clin.Immunol., 117, 2006
1DT1
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BU of 1dt1 by Molmil
THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI
分子名称: CYTOCHROME C552, HEME C
著者Fee, J.A, Chen, Y, Hill, M.J, Gomez-Moran, E, Loehr, T, Ai, J, Thony-Meyer, L, Williams, P.A, Stura, E, Sridhar, V, McRee, D.E.
登録日2000-01-10
公開日2000-02-18
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein.
Protein Sci., 9, 2000
3LJG
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BU of 3ljg by Molmil
Human MMP12 in complex with non-zinc chelating inhibitor
分子名称: ACETOHYDROXAMIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
著者Stura, E.A, Dive, V, Devel, L, Vera, L, Beau, F.
登録日2010-01-26
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.313 Å)
主引用文献Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
6R5M
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BU of 6r5m by Molmil
Crystal structure of toxin MT9 from mamba venom
分子名称: ACETYL GROUP, Dendroaspis polylepis MT9, GLYCEROL, ...
著者Stura, E.A, Tepshi, L, Ciolek, J, Triquigneaux, M, Zoukimian, C, De Waard, M, Beroud, R, Servent, D, Gilles, N, Legrand, P, Ciccone, L.
登録日2019-03-25
公開日2020-02-12
最終更新日2022-05-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Biomed Pharmacother, 150, 2022
8AJ7
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BU of 8aj7 by Molmil
Kunitz domain of Amblyomin-X
分子名称: 1,2-ETHANEDIOL, Kunitz domain of Amblyomin-X
著者Ciccone, L, Servent, D, Stura, E.A.
登録日2022-07-27
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity.
Front Mol Biosci, 10, 2023
3F58
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BU of 3f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120 (MN ISOLATE); H315S MUTATION
分子名称: PROTEIN (CYCLIC PEPTIDE (GP120)), PROTEIN (IMMUNOGLOBULIN GAMMA I (58.2))
著者Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
登録日1998-10-23
公開日1999-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2VLW
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BU of 2vlw by Molmil
Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative.
分子名称: ACETATE ION, MUSCARINIC M1-TOXIN1, SULFATE ION
著者Menez, R, Granata, V, Mourier, G, Fruchart-Gaillard, C, Menez, A, Servant, D, Stura, E.A.
登録日2008-01-17
公開日2008-10-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.
Mol.Pharmacol., 74, 2008
3LIR
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BU of 3lir by Molmil
Human MMP12 in complex with non-zinc chelating inhibitor
分子名称: CALCIUM ION, GLYCINE, Macrophage metalloelastase, ...
著者Stura, E.A, Dive, V, Devel, L, Czarny, B, Vera, L, Beau, F.
登録日2010-01-25
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
3LIL
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BU of 3lil by Molmil
Human MMP12 in complex with non-zinc chelating inhibitor
分子名称: ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ...
著者Stura, E.A, Dive, V, Devel, L, Czarny, B, Vera, L, Beau, F.
登録日2010-01-25
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
3LIK
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BU of 3lik by Molmil
Human MMP12 in complex with non-zinc chelating inhibitor
分子名称: ACETOHYDROXAMIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
著者Stura, E.A, Dive, V, Devel, L, Czarny, B, Vera, L, Beau, F.
登録日2010-01-25
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
2ZCH
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BU of 2zch by Molmil
Crystal structure of human prostate specific antigen complexed with an activating antibody
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, PHOSPHATE ION, ...
著者Menez, R, Stura, E, Jolivet-Reynaud, C.
登録日2007-11-08
公開日2008-01-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
2ZCL
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BU of 2zcl by Molmil
Crystal structure of human prostate specific antigen complexed with an activating antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostate-specific antigen, monoclonal antibody 8G8F5 Fab
著者Menez, R, Stura, E, Jolivet-Reynaud, C.
登録日2007-11-09
公開日2008-01-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
2ZCK
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BU of 2zck by Molmil
Crystal structure of a ternary complex between PSA, a substrat-acyl intermediate and an activating antibody
分子名称: KGISSQY, Prostate-specific antigen, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Menez, R, Stura, E, Jolivet-Reynaud, C.
登録日2007-11-09
公開日2008-01-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
2F58
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BU of 2f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
分子名称: 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ...
著者Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
登録日1998-10-23
公開日1999-02-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2H7Z
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BU of 2h7z by Molmil
Crystal structure of irditoxin
分子名称: Irditoxin subunit A, Irditoxin subunit B
著者Pawlak, J, Kini, R.M, Stura, E.A, Le Du, M.H.
登録日2006-06-06
公開日2006-08-29
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
Faseb J., 23, 2009
3NDS
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BU of 3nds by Molmil
Crystal structure of engineered Naja Nigricollis toxin alpha
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, SULFATE ION, Short neurotoxin 1
著者Stura, E.A, Drevet, P, Gregory, G, Gallopin, M, Vandame, M.
登録日2010-06-08
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Conformational exchange is critical for the productivity of an oxidative folding intermediate with buried free cysteines.
J.Mol.Biol., 403, 2010
3V95
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BU of 3v95 by Molmil
Crystal structure of monoclonal human anti-rhesus D Fc and IgG1 t125(yb2/0) in the presence of EDTA
分子名称: GLYCEROL, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Menez, R, A Stura, E, Bourel, D, Siberil, S, Jorieux, S, De Romeuf, C, Ducancel, F, Fridman, W.H, Teillaud, J.L.
登録日2011-12-23
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Effect of zinc on human IgG1 and its Fc gamma R interactions.
Immunol.Lett., 143, 2012
2H5F
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BU of 2h5f by Molmil
Denmotoxin: A the three-finger toxin from colubrid snake Boiga dendrophila with bird-specific activity
分子名称: PHOSPHATE ION, POTASSIUM ION, SODIUM ION, ...
著者Pawlak, J, Kini, R.M, Stura, E.A.
登録日2006-05-26
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
J.Biol.Chem., 281, 2006
1NLB
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BU of 1nlb by Molmil
crystal structure of anti-HCV monoclonal antibody 19D9D6
分子名称: antibody 19D9D6 heavy chain, antibody 19D9D6 light chain
著者Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E.
登録日2003-01-07
公開日2003-02-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003
1N64
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BU of 1n64 by Molmil
Crystal structure analysis of the immunodominant antigenic site on Hepatitis C virus protein bound to mAb 19D9D6
分子名称: Fab 19D9D6 heavy chain, Fab 19D9D6 light chain, Genome polyprotein Capsid protein C
著者Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E.
登録日2002-11-08
公開日2003-02-25
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003

 

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