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5E54
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Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser
分子名称: MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2015-10-07
公開日2016-11-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
4EYA
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BU of 4eya by Molmil
Crystal Structure of a Plectonemic RNA Supercoil
分子名称: GLYCEROL, N utilization substance protein B homolog, RNA (5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3'), ...
著者Stagno, J.R, Ji, X.
登録日2012-05-01
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a plectonemic RNA supercoil.
Nat Commun, 3, 2012
3R2D
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BU of 3r2d by Molmil
Crystal Structure of Antitermination Factors NusB and NusE in complex with dsRNA
分子名称: 30S ribosomal protein S10, 5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3', DI(HYDROXYETHYL)ETHER, ...
著者Stagno, J.R, Ji, X.
登録日2011-03-14
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.
Nucleic Acids Res., 39, 2011
3R2C
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BU of 3r2c by Molmil
Crystal Structure of Antitermination Factors NusB and NusE in complex with BoxA RNA
分子名称: 30S ribosomal protein S10, 5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3', ACETATE ION, ...
著者Stagno, J.R, Ji, X.
登録日2011-03-14
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.
Nucleic Acids Res., 39, 2011
5SWD
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BU of 5swd by Molmil
Structure of the adenine riboswitch aptamer domain in an intermediate-bound state
分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ...
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5SWE
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BU of 5swe by Molmil
Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography
分子名称: ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
6VWT
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Transitional unit cell 1 of adenine riboswitch aptamer crystal phase transition upon ligand binding
分子名称: ADENINE, MAGNESIUM ION, adenine riboswitch aptamer variant
著者Stagno, J.R, Wang, Y.-X.
登録日2020-02-20
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Synchronous RNA conformational changes trigger ordered phase transitions in crystals.
Nat Commun, 12, 2021
4U5T
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BU of 4u5t by Molmil
Crystal Structure of VBP Leucine Zipper with Bound Arylstibonic Acid
分子名称: (2Z)-3-{3-[dihydroxy(oxido)-lambda~5~-stibanyl]phenyl}prop-2-enoic acid, VBP leucine zipper
著者Stagno, J.R, Ji, X.
登録日2014-07-25
公開日2014-08-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA.
Mol.Pharmacol., 82, 2012
8FW4
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BU of 8fw4 by Molmil
Crystal structure of the adenosylcobalamin riboswitch holo conformation in absence of ligand
分子名称: MAGNESIUM ION, RNA (210-MER)
著者Stagno, J.R, Wang, Y.-X.
登録日2023-01-20
公開日2023-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Crystal structure of cobalamin ribositch in holo conformation without ligand
Nucleic Acids Res., 2023
6VWV
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Transitional unit cell 2 of adenine riboswitch aptamer crystal phase transition upon ligand binding
分子名称: ADENINE, MAGNESIUM ION, POTASSIUM ION, ...
著者Stagno, J.R, Wang, Y.-X.
登録日2020-02-20
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synchronous RNA conformational changes trigger ordered phase transitions in crystals.
Nat Commun, 12, 2021
5KAL
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BU of 5kal by Molmil
Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*U)-3'), RNA uridylyltransferase 4, ...
著者Stagno, J.R, Luecke, H, Afasizhev, R.
登録日2016-06-01
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Nucleic Acids Res., 44, 2016
8F4O
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BU of 8f4o by Molmil
Apo structure of the TPP riboswitch aptamer domain
分子名称: IRIDIUM HEXAMMINE ION, TETRAETHYLENE GLYCOL, TPP riboswitch aptamer domain, ...
著者Lee, H.-K, Wang, Y.-X, Stagno, J.R.
登録日2022-11-11
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state.
Structure, 31, 2023
7KD1
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BU of 7kd1 by Molmil
Apo structure of the THF riboswitch aptamer domain
分子名称: MAGNESIUM ION, SULFATE ION, tetrahydrofolate riboswitch aptamer domain
著者Wilt, H.M, Stagno, J.R, Wang, Y.-X.
登録日2020-10-07
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tying the knot in the tetrahydrofolate (THF) riboswitch: A molecular basis for gene regulation.
J.Struct.Biol., 213, 2021
6WJR
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Apo structure of the FMN riboswitch aptamer domain in the presence of sulfate
分子名称: MAGNESIUM ION, RNA (112-MER), SULFATE ION
著者Wilt, H.M, Wang, Y.-X, Stagno, J.R.
登録日2020-04-14
公開日2020-09-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations.
J Struct Biol X, 4, 2020
6WJS
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BU of 6wjs by Molmil
Apo structure of the FMN riboswitch aptamer domain in the presence of phosphate
分子名称: PHOSPHATE ION, RNA (112-MER)
著者Wilt, H.M, Wang, Y.-X, Stagno, J.R.
登録日2020-04-14
公開日2020-09-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations.
J Struct Biol X, 4, 2020
5UZA
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BU of 5uza by Molmil
Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (PLOR)
分子名称: ADENINE, MAGNESIUM ION, RNA (71-MER)
著者Liu, Y, Stagno, J.R, Wang, Y.-X.
登録日2017-02-25
公開日2018-02-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.
Nat Protoc, 13, 2018
8SA2
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BU of 8sa2 by Molmil
Adenosylcobalamin-bound riboswitch dimer, form 1
分子名称: Adenosylcobalamin, adenosylcobalamin riboswitch form 1
著者Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X.
登録日2023-03-31
公開日2023-07-26
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
8SA4
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Adenosylcobalamin-bound riboswitch dimer, form 3
分子名称: Adenosylcobalamin, adenosylcobalamin riboswitch form 3
著者Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X.
登録日2023-03-31
公開日2023-07-26
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
8SA3
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Adenosylcobalamin-bound riboswitch dimer, form 2
分子名称: Adenosylcobalamin, adenosylcobalamin riboswitch form 2
著者Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X.
登録日2023-03-31
公開日2023-07-26
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
8SA6
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apo form of adenosylcobalamin riboswitch dimer
分子名称: apo form of adenosylcobalamin riboswitch dimer
著者Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X.
登録日2023-03-31
公開日2023-07-26
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
8SA5
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BU of 8sa5 by Molmil
Adenosylcobalamin-bound riboswitch dimer, form 4
分子名称: Adenosylcobalamin, adenosylcobalamin riboswitch form 4
著者Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X.
登録日2023-03-31
公開日2023-07-26
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM.
Nucleic Acids Res., 51, 2023
4XNR
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Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine
分子名称: ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch
著者Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R.
登録日2015-01-16
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Synthesis and applications of RNAs with position-selective labelling and mosaic composition.
Nature, 522, 2015
6PQ7
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BU of 6pq7 by Molmil
Structure of the iMango-III fluorescent aptamer at room temperature.
分子名称: MAGNESIUM ION, POTASSIUM ION, RNA (37-MER), ...
著者Trachman III, R.J, Ferre-D'Amare, A.R.
登録日2019-07-08
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Co-crystal structure of the iMango-III fluorescent RNA aptamer using an X-ray free-electron laser.
Acta Crystallogr.,Sect.F, 75, 2019
5HZD
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BU of 5hzd by Molmil
RNA Editing TUTase 1 from Trypanosoma brucei
分子名称: 3' terminal uridylyl transferase, CHLORIDE ION, SULFATE ION, ...
著者Thore, S, Rajappa, L.T.
登録日2016-02-02
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Nucleic Acids Res., 44, 2016
5I49
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RNA Editing TUTase 1 from Trypanosoma brucei in complex with UTP analog UMPNPP
分子名称: 3' terminal uridylyl transferase, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ...
著者Thore, S, Rajappa, L.T.
登録日2016-02-11
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Nucleic Acids Res., 44, 2016

 

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