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1DV8
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BU of 1dv8 by Molmil
CRYSTAL STRUCTURE OF THE CARBOHYDRATE RECOGNITION DOMAIN OF THE H1 SUBUNIT OF THE ASIALOGLYCOPROTEIN RECEPTOR
分子名称: ASIALOGLYCOPROTEIN RECEPTOR 1, CALCIUM ION, CHLORIDE ION
著者Meier, M, Bider, M.D, Malashkevich, V.N, Spiess, M, Burkhard, P.
登録日2000-01-20
公開日2000-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the carbohydrate recognition domain of the H1 subunit of the asialoglycoprotein receptor.
J.Mol.Biol., 300, 2000
8DGZ
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BU of 8dgz by Molmil
Caspase-7 bound to substrate mimic and allosteric inhibitor
分子名称: 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}benzoic acid, Ac-Asp-Glu-Val-Asp-Aldehyde, Caspase-7
著者Propp, J, Kalenkiewicz, A, Kathryn, F.H, Spies, M.A.
登録日2022-06-24
公開日2023-07-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power.
Chemistry, 29, 2023
8DJ3
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BU of 8dj3 by Molmil
Caspase-7 bound to novel allosteric inhibitor
分子名称: 2-[(2-{[(3s,5s,7s)-adamantan-1-yl]sulfamoyl}phenyl)sulfanyl]benzoic acid, Caspase-7
著者Propp, J, Kalenkiewicz, A, Kathryn, F.H, Spies, M.A.
登録日2022-06-29
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power.
Chemistry, 29, 2023
6I52
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BU of 6i52 by Molmil
Yeast RPA bound to ssDNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ...
著者Yates, L.A, Aramayo, R.J, Zhang, X.
登録日2018-11-12
公開日2018-12-19
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Nat Commun, 9, 2018
9B8U
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BU of 9b8u by Molmil
Crystal structure of CRX-Ret4 oligonucleotide complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Cone-rod homeobox protein, ...
著者Srivastava, D, Artemyev, N.O.
登録日2024-04-01
公開日2024-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element.
Structure, 32, 2024
8TKQ
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BU of 8tkq by Molmil
Cryo-EM structure of human full-length RAD52
分子名称: DNA repair protein RAD52 homolog
著者Schnicker, N.J, Razzaghi, M, Spies, M.
登録日2023-07-25
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A double-ring of human RAD52 remodels replication forks restricting fork reversal
To Be Published
8DNY
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BU of 8dny by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by decatransin
分子名称: Decatransin peptide inhibitor, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DNX
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BU of 8dnx by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by cotransin
分子名称: Cotransin analogue peptide inhibitor, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DNZ
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BU of 8dnz by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F
分子名称: Apratoxin F peptide inhibitor, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DO3
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BU of 8do3 by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I
分子名称: N'-(4-chlorophenyl)-N-[(4R)-3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]hydrazinyl}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-N-hydroxyurea, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DNV
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BU of 8dnv by Molmil
Cryo-EM structure of the human Sec61 complex in a partially-open apo state (Class 1)
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DNW
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BU of 8dnw by Molmil
Cryo-EM structure of the human Sec61 complex in a partially-open apo state (Class 2)
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DO0
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BU of 8do0 by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by mycolactone
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DO2
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BU of 8do2 by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by cyclotriazadisulfonamide (CADA)
分子名称: 9-benzyl-1,5-bis(4-methylbenzene-1-sulfonyl)-3-methylidene-1,5,9-triazacyclododecane, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023
8DO1
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BU of 8do1 by Molmil
Cryo-EM structure of the human Sec61 complex inhibited by ipomoeassin F
分子名称: Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ...
著者Park, E, Itskanov, S.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献A common mechanism of Sec61 translocon inhibition by small molecules.
Nat.Chem.Biol., 19, 2023

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件を2024-10-16に公開中

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