6C5V
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![BU of 6c5v by Molmil](/molmil-images/mine/6c5v) | An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ... | 著者 | Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-01-16 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Immunity, 48, 2018
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5N8Y
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![BU of 5n8y by Molmil](/molmil-images/mine/5n8y) | KaiCBA circadian clock backbone model based on a Cryo-EM density | 分子名称: | Circadian clock protein KaiA, Circadian clock protein KaiB, Circadian clock protein kinase KaiC | 著者 | Schuller, J.M, Snijder, J, Loessl, P, Heck, A.J.R, Foerster, F. | 登録日 | 2017-02-24 | 公開日 | 2017-03-29 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state. Science, 355, 2017
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7BG1
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![BU of 7bg1 by Molmil](/molmil-images/mine/7bg1) | |
5SZS
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![BU of 5szs by Molmil](/molmil-images/mine/5szs) | Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Walls, A.C, Tortorici, M.A, Frenz, B, Snijder, J, Li, W, Rey, F.A, DiMaio, F, Bosch, B.J, Veesler, D. | 登録日 | 2016-08-15 | 公開日 | 2016-09-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy. Nat.Struct.Mol.Biol., 23, 2016
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6MYY
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![BU of 6myy by Molmil](/molmil-images/mine/6myy) | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | 登録日 | 2018-11-02 | 公開日 | 2018-11-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
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6U1T
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![BU of 6u1t by Molmil](/molmil-images/mine/6u1t) | Crystal structure of anti-Nipah virus (NiV) F 5B3 antibody Fab fragment | 分子名称: | CHLORIDE ION, antigen-binding (Fab) fragment, heavy chain, ... | 著者 | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C, Mire, C.E, BBroder, C.C, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-08-16 | 公開日 | 2019-10-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.483 Å) | 主引用文献 | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
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6TYS
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![BU of 6tys by Molmil](/molmil-images/mine/6tys) | A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ... | 著者 | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-08-09 | 公開日 | 2019-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
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6NB8
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![BU of 6nb8 by Molmil](/molmil-images/mine/6nb8) | Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment | 分子名称: | S230 antigen-binding (Fab) fragment, heavy chain, light chain | 著者 | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB5
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![BU of 6nb5 by Molmil](/molmil-images/mine/6nb5) | Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment | 分子名称: | LCA60 antigen-binding (Fab) fragment, heavy chain, light chain | 著者 | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6B3O
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![BU of 6b3o by Molmil](/molmil-images/mine/6b3o) | Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion | 分子名称: | Spike glycoprotein | 著者 | Walls, A.C, Tortorici, M.A, Snijder, J, Xiong, X, Bosch, B.J, Rey, F.A, Veesler, D. | 登録日 | 2017-09-22 | 公開日 | 2017-10-04 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6MZJ
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![BU of 6mzj by Molmil](/molmil-images/mine/6mzj) | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | 登録日 | 2018-11-05 | 公開日 | 2018-11-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
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8P6I
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![BU of 8p6i by Molmil](/molmil-images/mine/8p6i) | Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope | 分子名称: | 139H2 HC, 139H2 LC, Mucin-1 | 著者 | Beugelink, J.W, Peng, W, Siborova, M, Pronker, M.F, Snijder, J, Janssen, B.J.C. | 登録日 | 2023-05-26 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing. Life Sci Alliance, 7, 2024
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6BLA
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![BU of 6bla by Molmil](/molmil-images/mine/6bla) | Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ... | 著者 | Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2017-11-09 | 公開日 | 2018-04-25 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Immunity, 48, 2018
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8RMO
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![BU of 8rmo by Molmil](/molmil-images/mine/8rmo) | Crystal structure of anti-FLAG M2 Fab fragment bound to FLAG-tag peptide epitope | 分子名称: | CHLORIDE ION, FLAG-tag, anti-FLAG M2 heavy chain, ... | 著者 | Beugelink, J.W, Janssen, B.J.C, Pronker, M.F. | 登録日 | 2024-01-08 | 公開日 | 2024-04-03 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.163 Å) | 主引用文献 | Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2. J.Mol.Biol., 436, 2024
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6Y3Y
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![BU of 6y3y by Molmil](/molmil-images/mine/6y3y) | Human Coronavirus HKU1 Haemagglutinin-Esterase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ... | 著者 | Hurdiss, D.L, Drulyte, I, Pronker, M.F. | 登録日 | 2020-02-19 | 公開日 | 2020-04-08 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans. Nat Commun, 11, 2020
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6BFU
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![BU of 6bfu by Molmil](/molmil-images/mine/6bfu) | Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ... | 著者 | Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D. | 登録日 | 2017-10-27 | 公開日 | 2017-11-22 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections. J. Virol., 92, 2018
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6NB4
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![BU of 6nb4 by Molmil](/molmil-images/mine/6nb4) | MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB7
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![BU of 6nb7 by Molmil](/molmil-images/mine/6nb7) | SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB6
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![BU of 6nb6 by Molmil](/molmil-images/mine/6nb6) | SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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6NB3
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![BU of 6nb3 by Molmil](/molmil-images/mine/6nb3) | MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ... | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-12-06 | 公開日 | 2019-02-06 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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7PNM
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![BU of 7pnm by Molmil](/molmil-images/mine/7pnm) | |
7PO5
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![BU of 7po5 by Molmil](/molmil-images/mine/7po5) | |
7PNQ
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6MFT
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![BU of 6mft by Molmil](/molmil-images/mine/6mft) | Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Weidle, C, Pancera, M, Stamatatos, L, Gray, M. | 登録日 | 2018-09-12 | 公開日 | 2018-11-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.315 Å) | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
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6T3W
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![BU of 6t3w by Molmil](/molmil-images/mine/6t3w) | Coxsackie B3 2C protein in complex with S-Fluoxetine | 分子名称: | (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, SODIUM ION, ... | 著者 | El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B. | 登録日 | 2019-10-11 | 公開日 | 2020-11-18 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex. Sci Adv, 8, 2022
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