4KYW
 
 | | Restriction endonuclease DPNI in complex with two DNA molecules | | 分子名称: | 5'-(*DC*DTP*DGP*DGP*6MAP*DTP*DCP*DCP*DAP*DG)-3', CALCIUM ION, SODIUM ION, ... | | 著者 | Mierzejewska, K, Siwek, W, Czapinska, H, Skowronek, K, Bujnicki, J.M, Bochtler, M. | | 登録日 | 2013-05-29 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res., 42, 2014
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4ESJ
 | | RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA | | 分子名称: | AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ... | | 著者 | Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K. | | 登録日 | 2012-04-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
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1XJ0
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8BV8
 | | Crystal structure of the phage Mu protein Mom inactive mutant S124A | | 分子名称: | Methylcarbamoylase mom | | 著者 | Silva, R.M.B, Slyvka, A, Lee, Y.J, Guan, C, Lund, S.R, Raleigh, E.A, Skowronek, K, Bochtler, M, Weigele, P.R. | | 登録日 | 2022-12-08 | | 公開日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal structure of the phage Mu protein Mom catalytic mutant S124A
To Be Published
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8BPR
 | | Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction). | | 分子名称: | DNA repair protein RecO, DNA replication and repair protein RecF, MAGNESIUM ION, ... | | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | 登録日 | 2022-11-17 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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7ZVX
 | | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution | | 分子名称: | 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ... | | 著者 | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | | 登録日 | 2022-05-17 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
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7ZVN
 | | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution | | 分子名称: | 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ... | | 著者 | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
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8A8J
 | | Complex of RecF and DNA from Thermus thermophilus. | | 分子名称: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | 登録日 | 2022-06-23 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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8A93
 | | Complex of RecF-RecR-DNA from Thermus thermophilus. | | 分子名称: | DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ... | | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | 登録日 | 2022-06-27 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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8AB0
 | | Complex of RecO-RecR-DNA from Thermus thermophilus. | | 分子名称: | DNA repair protein RecO, Oligo1, Oligo2, ... | | 著者 | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | | 登録日 | 2022-07-04 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (6.09 Å) | | 主引用文献 | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
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6QM2
 | | NlaIV restriction endonuclease | | 分子名称: | POTASSIUM ION, SODIUM ION, Type-2 restriction enzyme NlaIV | | 著者 | Czapinska, H, Siwek, W, Szczepanowski, R.H, Bujnicki, J.M, Bochtler, M, Skowronek, K. | | 登録日 | 2019-02-01 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.
J.Mol.Biol., 431, 2019
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4OUN
 | | Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis | | 分子名称: | Mini-ribonuclease 3 | | 著者 | Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M. | | 登録日 | 2014-02-18 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Sequence-specific cleavage of dsRNA by Mini-III RNase
Nucleic Acids Res., 43, 2015
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8OZ7
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3PIH
 | | T. maritima UvrA in complex with fluorescein-modified DNA | | 分子名称: | DNA (32-MER), PYROPHOSPHATE, UvrABC system protein A, ... | | 著者 | Jaciuk, M, Nowak, E, Nowotny, M. | | 登録日 | 2010-11-06 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Nat.Struct.Mol.Biol., 18, 2011
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8AUP
 | | Structure of hARG1 with a novel inhibitor. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ... | | 著者 | Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol.Cancer Ther., 22, 2023
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7O24
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7O0H
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7O0G
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7R08
 | | Abortive infection DNA polymerase Abi-P2 | | 分子名称: | Reverse transcriptase | | 著者 | Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R06
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | 分子名称: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3') | | 著者 | Figiel, M, Nowotny, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7R07
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis | | 分子名称: | AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MAGNESIUM ION | | 著者 | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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7Z0Z
 | | Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant | | 分子名称: | AbiK | | 著者 | Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M. | | 登録日 | 2022-02-24 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
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