6MFD
 
 | | GphF GNAT-like decarboxylase in complex with isobutyryl-CoA | | 分子名称: | ACETATE ION, GLYCEROL, GphF, ... | | 著者 | Skiba, M.A, Tran, C.L, Smith, J.L. | | 登録日 | 2018-09-10 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
Structure, 28, 2020
|
|
6MFC
 | |
8TH4
 | |
8TH3
 | |
6B39
 | | AprA Methyltransferase 1 - GNAT in complex with SAH | | 分子名称: | AprA Methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | 著者 | Skiba, M.A, Smith, J.L. | | 登録日 | 2017-09-21 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.392 Å) | | 主引用文献 | A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.
ACS Chem. Biol., 12, 2017
|
|
6B3A
 | |
6B3B
 | | AprA Methyltransferase 1 - GNAT in complex with Mn2+ , SAM, and Malonate | | 分子名称: | AprA Methyltransferase 1, GLYCEROL, MALONATE ION, ... | | 著者 | Skiba, M.A, Smith, J.L. | | 登録日 | 2017-09-21 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.
ACS Chem. Biol., 12, 2017
|
|
6ECW
 | |
6ECX
 | |
6ECV
 | |
6ECT
 | |
6ECU
 | |
5THZ
 | |
5THY
 | |
7UCH
 | | AprA Methyltransferase 1 - GNAT in complex with Mn2+ , SAM, and Di-methyl-malonate | | 分子名称: | AprA Methyltransferase 1, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Skiba, M.A, Lao, Y, Smith, J.L. | | 登録日 | 2022-03-16 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C -Methyltransferases.
Acs Chem.Biol., 17, 2022
|
|
7T83
 | |
6OS0
 | | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, CHLORIDE ION, ... | | 著者 | Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C. | | 登録日 | 2019-05-01 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
|
|
6OS1
 | | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Nanobody Nb.AT110i1_le, ... | | 著者 | Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C. | | 登録日 | 2019-05-01 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
|
|
6OS2
 | | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C. | | 登録日 | 2019-05-01 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
|
|
5VE5
 | | Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans in complex with glutathione | | 分子名称: | BpPRF, CHLORIDE ION, FE (III) ION, ... | | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | | 登録日 | 2017-04-03 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.
J. Biol. Chem., 292, 2017
|
|
5VE3
 | | Crystal structure of wild-type persulfide dioxygenase-rhodanese fusion protein from Burkholderia phytofirmans | | 分子名称: | BpPRF, FE (III) ION | | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | | 登録日 | 2017-04-03 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.793 Å) | | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.
J. Biol. Chem., 292, 2017
|
|
5VE4
 | | Crystal structure of persulfide dioxygenase-rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans | | 分子名称: | BpPRF, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | | 登録日 | 2017-04-03 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.
J. Biol. Chem., 292, 2017
|
|
7T84
 | | Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32 G26D T57I variant | | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Nemeth, G.R, Skiba, M.A, Kruse, A.C. | | 登録日 | 2021-12-15 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An in silico method to assess antibody fragment polyreactivity.
Nat Commun, 13, 2022
|
|
7TJ4
 | | Structure of the S. aureus amidase LytH and activator ActH extracellular domains | | 分子名称: | ActH, LytH, ZINC ION | | 著者 | Page, J.E, Skiba, M.A, Kruse, A.C, Walker, S. | | 登録日 | 2022-01-14 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UCI
 | | SxtA Methyltransferase and decarboxylase didomain in complex with Mn2+ and SAH | | 分子名称: | GLYCEROL, MANGANESE (II) ION, Polyketide synthase-related protein, ... | | 著者 | Lao, Y, Skiba, M.A, Smith, J.L. | | 登録日 | 2022-03-16 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C -Methyltransferases.
Acs Chem.Biol., 17, 2022
|
|
