7T83

Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32

Summary for 7T83

• Entry DOI: 10.2210/pdb7t83/pdb
• Descriptor: Nanobody AT118i4h32, CITRATE ANION (3 entities in total)
• Functional Keywords: single chain antibody fragment, immune system
• Biological source: synthetic construct
• Total number of polymer chains: 8
• Total formula weight: 114563.28

Authors

Skiba, M.A.,Kruse, A.C. (deposition date: 2021-12-15, release date: 2022-12-07, Last modification date: 2023-10-25)

• Primary citation: Harvey, E.P.,Shin, J.E.,Skiba, M.A.,Nemeth, G.R.,Hurley, J.D.,Wellner, A.,Shaw, A.Y.,Miranda, V.G.,Min, J.K.,Liu, C.C.,Marks, D.S.,Kruse, A.C.; An in silico method to assess antibody fragment polyreactivity.; Nat Commun, 13:7554-7554, 2022; PubMed: 36477674; DOI: 10.1038/s41467-022-35276-4

Experimental method

X-RAY DIFFRACTION (2.1 Å)