7R7G
 
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7R7F
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7R7E
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7LWZ
 | | Apo Structure of Vibrio cholerae dGTPase protein VC1979 | | 分子名称: | Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1, NICKEL (II) ION | | 著者 | Sikkema, A.P, Horng, J, Klemm, B.P, Schaaper, R.M, Hall, T.M.T. | | 登録日 | 2021-03-02 | | 公開日 | 2021-03-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structure of Vibrio cholerae dGTPase protein VC1979
To Be Published
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5WM4
 | | Crystal Structure of CahJ in Complex with 6-Methylsalicyl Adenylate | | 分子名称: | 9-(5-O-{(S)-hydroxy[(2-hydroxy-6-methylbenzene-1-carbonyl)oxy]phosphoryl}-alpha-L-lyxofuranosyl)-9H-purin-6-amine, ACETATE ION, GLYCEROL, ... | | 著者 | Sikkema, A.P, Smith, J.L. | | 登録日 | 2017-07-28 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.781 Å) | | 主引用文献 | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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5WM2
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5WM5
 | | Crystal Structure of CahJ in Complex with 5-Methylsalicyl Adenylate | | 分子名称: | 9-(5-O-{(S)-hydroxy[(2-hydroxy-5-methylbenzene-1-carbonyl)oxy]phosphoryl}-alpha-L-lyxofuranosyl)-9H-purin-6-amine, ACETATE ION, GLYCEROL, ... | | 著者 | Sikkema, A.P, Smith, J.L. | | 登録日 | 2017-07-28 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | | 主引用文献 | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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5WM3
 | | Crystal Structure of CahJ in Complex with Salicyl Adenylate | | 分子名称: | 9-(5-O-{(S)-hydroxy[(2-hydroxybenzene-1-carbonyl)oxy]phosphoryl}-alpha-L-lyxofuranosyl)-9H-purin-6-amine, ACETATE ION, GLYCEROL, ... | | 著者 | Sikkema, A.P, Smith, J.L. | | 登録日 | 2017-07-28 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.679 Å) | | 主引用文献 | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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5WM6
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5WM7
 | | Crystal Structure of CahJ in Complex with AMP | | 分子名称: | ACETATE ION, ADENOSINE MONOPHOSPHATE, GLYCEROL, ... | | 著者 | Sikkema, A.P, Smith, J.L. | | 登録日 | 2017-07-28 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.777 Å) | | 主引用文献 | A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
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6D6Y
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7TU0
 | | Structure of the L. blandensis dGTPase bound to Mn | | 分子名称: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU1
 | | Structure of the L. blandensis dGTPase R37A mutant | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU2
 | | Structure of the L. blandensis dGTPase R37A mutant bound to Mn | | 分子名称: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU3
 | | Structure of the L. blandensis dGTPase del55-58 mutant | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU4
 | | Structure of the L. blandensis dGTPase del55-58 mutant bound to Mn | | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU6
 | | Structure of the L. blandensis dGTPase bound to dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU7
 | | Structure of the L. blandensis dGTPase H125A mutant bound to dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU8
 | | Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU5
 | | Structure of the L. blandensis dGTPase in the apo form | | 分子名称: | MAGNESIUM ION, dGTP triphosphohydrolase | | 著者 | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | 登録日 | 2022-02-02 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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5KCI
 | | Crystal Structure of HTC1 | | 分子名称: | GLYCEROL, SULFATE ION, Uncharacterized protein YPL067C, ... | | 著者 | Martin, R.M, Horowitz, S, Koepnick, B, Cooper, S, Flatten, J, Rogawski, D.S, Koropatkin, N.M, Beinlich, F.R.M, Players, F, Students, U.M, Popovic, Z, Baker, D, Khatib, F, Bardwell, J.C.A. | | 登録日 | 2016-06-06 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.833 Å) | | 主引用文献 | Determining crystal structures through crowdsourcing and coursework.
Nat Commun, 7, 2016
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5THZ
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5THY
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6MFD
 | | GphF GNAT-like decarboxylase in complex with isobutyryl-CoA | | 分子名称: | ACETATE ION, GLYCEROL, GphF, ... | | 著者 | Skiba, M.A, Tran, C.L, Smith, J.L. | | 登録日 | 2018-09-10 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
Structure, 28, 2020
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6MFC
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