5WM4
Crystal Structure of CahJ in Complex with 6-Methylsalicyl Adenylate
Summary for 5WM4
Entry DOI | 10.2210/pdb5wm4/pdb |
Descriptor | Salicylate-AMP ligase, 9-(5-O-{(S)-hydroxy[(2-hydroxy-6-methylbenzene-1-carbonyl)oxy]phosphoryl}-alpha-L-lyxofuranosyl)-9H-purin-6-amine, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | ligase, adenylation domain, peptide synthetase |
Biological source | Streptomyces gandocaensis |
Total number of polymer chains | 1 |
Total formula weight | 61827.64 |
Authors | Sikkema, A.P.,Smith, J.L. (deposition date: 2017-07-28, release date: 2018-05-23, Last modification date: 2023-10-04) |
Primary citation | Tripathi, A.,Park, S.R.,Sikkema, A.P.,Cho, H.J.,Wu, J.,Lee, B.,Xi, C.,Smith, J.L.,Sherman, D.H. A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ. Chembiochem, 19:1595-1600, 2018 Cited by PubMed: 29742306DOI: 10.1002/cbic.201800233 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.781 Å) |
Structure validation
Download full validation report