5WM5

Crystal Structure of CahJ in Complex with 5-Methylsalicyl Adenylate

Summary for 5WM5

Entry DOI	10.2210/pdb5wm5/pdb
Descriptor	Salicylate-AMP ligase, 9-(5-O-{(S)-hydroxy[(2-hydroxy-5-methylbenzene-1-carbonyl)oxy]phosphoryl}-alpha-L-lyxofuranosyl)-9H-purin-6-amine, ACETATE ION, ... (5 entities in total)
Functional Keywords	ligase, adenylation domain, peptide synthetase
Biological source	Streptomyces gandocaensis
Total number of polymer chains	1
Total formula weight	61475.06
Authors	Sikkema, A.P.,Smith, J.L. (deposition date: 2017-07-28, release date: 2018-05-23, Last modification date: 2023-10-04)
Primary citation	Tripathi, A.,Park, S.R.,Sikkema, A.P.,Cho, H.J.,Wu, J.,Lee, B.,Xi, C.,Smith, J.L.,Sherman, D.H. A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ. Chembiochem, 19:1595-1600, 2018 Cited by PubMed: 29742306 DOI: 10.1002/cbic.201800233 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.797 Å)

Structure validation