5EQU
 
 | | Crystal structure of the epimerase SnoN in complex with Fe3+, alpha ketoglutarate and nogalamycin RO | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Nogalamycin RO, ... | | 著者 | Selvaraj, B, Lindqvist, Y, Siitonen, V, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2015-11-13 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5ERL
 | | Crystal structure of the epimerase SnoN in complex with Ni2+, succinate and nogalamycin RO | | 分子名称: | NICKEL (II) ION, Nogalamycin RO, SUCCINIC ACID, ... | | 著者 | Selvaraj, B, Lindqvist, Y, Siitonen, V, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2015-11-14 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EP9
 | | Crystal structure of the non-heme alpha ketoglutarate dependent epimerase SnoN from nogalamycin biosynthesis | | 分子名称: | 2-OXOGLUTARIC ACID, ACETATE ION, FE (III) ION, ... | | 著者 | Selvaraj, B, Lindqvist, Y, Niiranen, L, Siitonen, V, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2015-11-11 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EPA
 | | Crystal structure of non-heme alpha ketoglutarate dependent carbocyclase SnoK from nogalamycin biosynthesis | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, MAGNESIUM ION, ... | | 著者 | Selvaraj, B, Lindqvist, Y, Siitonen, V, Niiranen, L, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2015-11-11 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4AN4
 | | Crystal structure of the glycosyltransferase SnogD from Streptomyces nogalater | | 分子名称: | DEOXYURIDINE-5'-DIPHOSPHATE, GLYCOSYL TRANSFERASE | | 著者 | Claesson, M, Siitonen, V, Dobritzsch, D, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2012-03-15 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of the Glycosyltransferase Snogd from the Biosynthetic Pathway of the Nogalamycin in Streptomyces Nogalater.
FEBS J., 279, 2012
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4AMB
 | | Crystal structure of the glycosyltransferase SnogD from Streptomyces nogalater | | 分子名称: | DEOXYURIDINE-5'-DIPHOSPHATE, SNOGD | | 著者 | Claesson, M, Siitonen, V, Dobritzsch, D, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2012-03-08 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal Structure of the Glycosyltransferase Snogd from the Biosynthetic Pathway of the Nogalamycin in Streptomyces Nogalater.
FEBS J., 279, 2012
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4AMG
 | | Crystal structure of the glycosyltransferase SnogD from Streptomyces nogalater | | 分子名称: | SNOGD | | 著者 | Claesson, M, Siitonen, V, Dobritzsch, D, Metsa-Ketela, M, Schneider, G. | | 登録日 | 2012-03-09 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal Structure of the Glycosyltransferase Snogd from the Biosynthetic Pathway of the Nogalamycin in Streptomyces Nogalater.
FEBS J., 279, 2012
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5BKA
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6VW4
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6P77
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6P7L
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7OWB
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-hydroxylase CalMB | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-06-17 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7OY1
 | | DnrK mutant RTCR | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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8R2E
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8R2J
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8R2B
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8R20
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7PHF
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PGA
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PHD
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, GLYCEROL, S-ADENOSYLMETHIONINE, ... | | 著者 | Grocholski, T, Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PHE
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PGJ
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-decarboxylate TamK and 10-hydroxylase RdmB, together with a single point mutation F297G | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-7-methoxy-2,4,5-tris(oxidanyl)-6,11-bis(oxidanylidene)-3,4-dihydro-1H-tetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-14 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PG7
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