8BH1
 
 | | Core divisome complex FtsWIQBL from Pseudomonas aeruginosa | | 分子名称: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ, ... | | 著者 | Kaeshammer, L, van den Ent, F, Jeffery, M, Lowe, J. | | 登録日 | 2022-10-28 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL.
Nat Microbiol, 8, 2023
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1YR2
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6S85
 | | Cutting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and dsDNA. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (31-MER), DNA (32-MER), ... | | 著者 | Kaeshammer, L, Saathoff, J.H, Gut, F, Bartho, J, Alt, A, Kessler, B, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-07-08 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.
Mol.Cell, 76, 2019
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6S6V
 | | Resting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ATPgS | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, Nuclease SbcCD subunit C, ... | | 著者 | Kaeshammer, L, Saathoff, J.H, Gut, F, Bartho, J, Alt, A, Kessler, B, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-07-03 | | 公開日 | 2019-09-04 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.
Mol.Cell, 76, 2019
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1NCH
 | | STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS | | 分子名称: | N-CADHERIN, YTTERBIUM (III) ION | | 著者 | Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A. | | 登録日 | 1995-03-23 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
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1NCG
 | | STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS | | 分子名称: | N-CADHERIN, YTTERBIUM (III) ION | | 著者 | Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A. | | 登録日 | 1995-03-23 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
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1NCI
 | | STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS | | 分子名称: | N-CADHERIN, URANYL (VI) ION | | 著者 | Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A. | | 登録日 | 1995-03-23 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
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1NEU
 | | STRUCTURE OF MYELIN MEMBRANE ADHESION MOLECULE P0 | | 分子名称: | MYELIN P0 PROTEIN | | 著者 | Shapiro, L, Doyle, J.P, Hensley, P, Colman, D.R, Hendrickson, W.A. | | 登録日 | 1996-09-24 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin.
Neuron, 17, 1996
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1C28
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1U9U
 | | Crystal structure of F58Y mutant of cytochrome b5 | | 分子名称: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shan, L, Lu, J.-X, Gan, J.-H, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | | 登録日 | 2004-08-11 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions.
Acta Crystallogr.,Sect.D, 61, 2005
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1U9M
 | | Crystal structure of F58W mutant of cytochrome b5 | | 分子名称: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shan, L, Lu, J.-X, Gan, J.-H, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | | 登録日 | 2004-08-10 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions.
Acta Crystallogr.,Sect.D, 61, 2005
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6AUO
 | | Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112F | | 分子名称: | N-biotin-C-Co4(mu3-O)4(Py)3(H2O)4-beta-alanine, Streptavidin | | 著者 | Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S. | | 登録日 | 2017-09-01 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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6AUC
 | | Artificial metalloproteins containing a Co4O4 active site - 2xm-Sav | | 分子名称: | N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine, Streptavidin | | 著者 | Olshansky, L, Vallapurackal, J, Huerta-Lavorie, R, Tilley, T.D, Borovik, A.S. | | 登録日 | 2017-08-31 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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6AUH
 | | Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112Y-a | | 分子名称: | N-biotin-C-Co4(mu3-O)4(OAc)(Py)3(H2O)3-beta-alanine, Streptavidin | | 著者 | Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S. | | 登録日 | 2017-09-01 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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6AUE
 | | Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112Y-b | | 分子名称: | N-biotin-C-Co4(mu3-O)4(OAc)(Py)4(H2O)3-beta-alanine, Streptavidin | | 著者 | Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S. | | 登録日 | 2017-08-31 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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6AUL
 | | Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112Y-b | | 分子名称: | BIOTIN, Streptavidin | | 著者 | Olshansky, L, Vallapurakal, J, Huerta-Lavorie, R, Nguyen, A.I, Tilley, T.D, Borovik, A.S. | | 登録日 | 2017-09-01 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
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7W2I
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2PQE
 | | Solution structure of proline-free mutant of staphylococcal nuclease | | 分子名称: | Thermonuclease | | 著者 | Shan, L, Tong, Y, Xie, T, Wang, M, Wang, J. | | 登録日 | 2007-05-01 | | 公開日 | 2007-06-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.
Biochemistry, 46, 2007
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7U5V
 | | Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide | | 分子名称: | Borealin, Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | An, S, Cho, U.S, Oh, H, Sha, L, Xu, J, Kim, S, Yang, W, An, W, Dou, Y. | | 登録日 | 2022-03-02 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Non-canonical MLL1 activity regulates centromeric phase separation and genome stability.
Nat.Cell Biol., 25, 2023
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2BKL
 | | Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Inter-Domain Dynamics in Catalysis and Specificity | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, N-[(BENZYLOXY)CARBONYL]-L-ALANYL-L-PROLINE, PROLYL ENDOPEPTIDASE, ... | | 著者 | Khosla, C, Shan, L, Mathews, I.I. | | 登録日 | 2005-02-16 | | 公開日 | 2005-03-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity
Proc.Natl.Acad.Sci.USA, 102, 2005
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6WUD
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6WU7
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6WIB
 | | Next generation monomeric IgG4 Fc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION | | 著者 | Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N. | | 登録日 | 2020-04-09 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
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6WMH
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6WNA
 | | Next generation monomeric IgG4 Fc | | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... | | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | | 登録日 | 2020-04-22 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
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