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2ROL
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BU of 2rol by Molmil
Structural Basis of PxxDY motif recognition in SH3 binding
分子名称: 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1
著者Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P.
登録日2008-04-02
公開日2009-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis of PxxDY motif recognition in SH3 binding
J.Mol.Biol., 382, 2008
5I22
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BU of 5i22 by Molmil
Amphiphysin SH3 in complex with Chikungunya virus nsP3 peptide
分子名称: CHIKV nsP3 peptide, Myc box-dependent-interacting protein 1
著者Tossavainen, H, Aitio, O, Hellman, M, Saksela, K, Permi, P.
登録日2016-02-04
公開日2016-06-15
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2.
J.Biol.Chem., 291, 2016
2K2M
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BU of 2k2m by Molmil
Structural Basis of PxxDY Motif Recognition in SH3 Binding
分子名称: Eps8-like protein 1
著者Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P.
登録日2008-04-02
公開日2009-02-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis of PxxDY motif recognition in SH3 binding.
J.Mol.Biol., 382, 2008
2KXC
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BU of 2kxc by Molmil
1H, 13C, and 15N Chemical Shift Assignments for IRTKS-SH3 and EspFu-R47 complex
分子名称: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, EspF-like protein
著者Aitio, O, Hellman, M, Kazlauskas, A, Vingadassalom, D.F, Leong, J.M, Saksela, K, Permi, P.
登録日2010-04-30
公開日2010-11-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly
Proc.Natl.Acad.Sci.USA, 107, 2010
2LNH
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BU of 2lnh by Molmil
Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly
分子名称: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, Neural Wiskott-Aldrich syndrome protein, Secreted effector protein EspF(U)
著者Aitio, O, Hellman, M, Skehan, B, Kesti, T, Leong, J.M, Saksela, K, Permi, P.
登録日2011-12-28
公開日2012-08-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.
Structure, 20, 2012
1EFN
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BU of 1efn by Molmil
HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
分子名称: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
著者Lee, C.-H, Kuriyan, J.
登録日1996-06-29
公開日1997-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
7OJ9
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BU of 7oj9 by Molmil
NMR solution structure of SNX9 SH3 - EEEV nsP3 peptide complex
分子名称: EEEV nsP3 peptide, Sorting nexin-9
著者Tossavainen, H, Permi, P.
登録日2021-05-14
公開日2022-04-13
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs.
Structure, 30, 2022
8C1V
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BU of 8c1v by Molmil
SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sb92, ...
著者Huiskonen, J.T, Rissanen, I, Hannula, L.
登録日2022-12-21
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants.
Nat Commun, 14, 2023
3RBB
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BU of 3rbb by Molmil
HIV-1 NEF protein in complex with engineered HCK SH3 domain
分子名称: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK
著者Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M.
登録日2011-03-29
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
Traffic, 12, 2011
4ORZ
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BU of 4orz by Molmil
HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19
著者Geyer, M, Lulf, S.
登録日2014-02-12
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody.
Retrovirology, 11, 2014
4D8D
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BU of 4d8d by Molmil
Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant
分子名称: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn
著者Arold, S.T, Hoh, F, Dumas, C.
登録日2012-01-10
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5201 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
1AVZ
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BU of 1avz by Molmil
V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
分子名称: FYN TYROSINE KINASE, NEGATIVE FACTOR
著者Arold, S, Franken, P, Dumas, C.
登録日1997-09-23
公開日1998-03-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
1QA5
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BU of 1qa5 by Molmil
MYRISTOYLATED HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES
分子名称: PROTEIN (MYRISTOYLATED HIV-1 NEF ANCHOR DOMAIN (MYRISTATE-GLY2 TO TRP57))
著者Geyer, M, Kalbitzer, H.R.
登録日1999-04-12
公開日1999-05-26
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
J.Mol.Biol., 289, 1999
1QA4
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BU of 1qa4 by Molmil
HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES
分子名称: Protein Nef
著者Geyer, M, Kalbitzer, H.R.
登録日1999-04-12
公開日1999-05-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
J.Mol.Biol., 289, 1999
1AVV
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BU of 1avv by Molmil
HIV-1 NEF PROTEIN, UNLIGANDED CORE DOMAIN
分子名称: NEGATIVE FACTOR
著者Arold, S, Franken, P, Dumas, C.
登録日1997-09-21
公開日1998-03-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997

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件を2024-07-03に公開中

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