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4UP5
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BU of 4up5 by Molmil
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
分子名称: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
著者Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
登録日2014-06-12
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
分子名称: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
著者Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
登録日2014-06-11
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
1W09
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BU of 1w09 by Molmil
Solution structure of the cis form of the human alpha-hemoglobin stabilizing protein (AHSP)
分子名称: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
著者Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
登録日2004-05-25
公開日2004-06-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
2FEJ
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BU of 2fej by Molmil
Solution structure of human p53 DNA binding domain.
分子名称: Cellular tumor antigen p53, ZINC ION
著者Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R.
登録日2005-12-16
公開日2006-01-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of p53 core domain: Structural basis for its instability
Proc.Natl.Acad.Sci.Usa, 103, 2006
7NWJ
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BU of 7nwj by Molmil
Solution NMR structure of the N-terminal domain of CEP164 (1-109)
分子名称: Centrosomal protein of 164 kDa
著者van Breugel, M, Rutherford, T.J.
登録日2021-03-16
公開日2021-09-15
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
3ZPV
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BU of 3zpv by Molmil
Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain
分子名称: PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION
著者Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M.
登録日2013-03-02
公開日2013-10-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
1W0B
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BU of 1w0b by Molmil
Solution structure of the human alpha-hemoglobin stabilizing protein (AHSP) P30A mutant
分子名称: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
著者Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
登録日2004-06-01
公開日2004-06-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
1W0A
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BU of 1w0a by Molmil
Solution structure of the trans form of the human alpha-hemoglobin stabilizing protein (AHSP)
分子名称: ALPHA-HEMOGLOBIN STABILIZING PROTEIN
著者Santiveri, C.M, Perez-Canadillas, J.M, Vadivelu, M.K, Allen, M.D, Rutherford, T.J, Watkins, N.A, Bycroft, M.
登録日2004-06-01
公開日2004-06-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.
J. Biol. Chem., 279, 2004
2UWQ
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BU of 2uwq by Molmil
Solution structure of ASPP2 N-terminus
分子名称: APOPTOSIS-STIMULATING OF P53 PROTEIN 2
著者Tidow, H, Rutherford, T.J, Andreeva, A, Fersht, A.R.
登録日2007-03-22
公開日2007-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.
J. Mol. Biol., 371, 2007
2VY5
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BU of 2vy5 by Molmil
U11-48K CHHC Zn-finger protein domain
分子名称: U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
著者Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
登録日2008-07-18
公開日2009-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.
Structure, 17, 2009
2WXC
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BU of 2wxc by Molmil
The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family.
分子名称: DIHYDROLIPOYLTRANSSUCCINASE
著者Neuweiler, H, Sharpe, T.D, Rutherford, T.J, Johnson, C.M, Allen, M.D, Ferguson, N, Fersht, A.R.
登録日2009-11-06
公開日2009-11-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Folding Mechanism of Bbl: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family.
J.Mol.Biol., 390, 2009
2WQG
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BU of 2wqg by Molmil
SAP domain from Tho1: L31W (fluorophore) mutant
分子名称: PROTEIN THO1
著者Dodson, C.A, Ferguson, N, Rutherford, T.J, Johnson, C.M, Fersht, A.R.
登録日2009-08-21
公開日2010-02-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Engineering a Two-Helix Bundle Protein for Folding Studies.
Protein Eng.Des.Sel., 23, 2010
2XB1
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BU of 2xb1 by Molmil
Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ...
著者Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M.
登録日2010-04-01
公開日2010-07-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
2VY4
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BU of 2vy4 by Molmil
U11-48K CHHC ZN-FINGER DOMAIN
分子名称: U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
著者Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
登録日2008-07-17
公開日2009-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.
Structure, 17, 2009
5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-05
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
6T8G
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BU of 6t8g by Molmil
Stalled FtsK motor domain bound to dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8B
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BU of 6t8b by Molmil
FtsK motor domain with dsDNA, translocating state
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, MAGNESIUM ION, ...
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8O
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BU of 6t8o by Molmil
Stalled FtsK motor domain bound to dsDNA end
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
7O6U
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BU of 7o6u by Molmil
Crystal structure of the VIN3 VEL polymerising domain (R554A R556D mutant)
分子名称: Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6T
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BU of 7o6t by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (R556D I575D mutant)
分子名称: MAGNESIUM ION, Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6V
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BU of 7o6v by Molmil
Crystal structure of the VEL1 VEL polymerising domain (R643A K645D I664D mutant)
分子名称: VIN3-like protein 2
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6W
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BU of 7o6w by Molmil
Crystal structure of (the) VEL1 VEL polymerising domain (I664D mutant)
分子名称: PHOSPHATE ION, VIN3-like protein 2
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7OQV
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BU of 7oqv by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (I575D mutant)
分子名称: Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-06-04
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7QCE
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BU of 7qce by Molmil
Crystal structure of an atypical PHD finger of VIN3
分子名称: DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION
著者Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M.
登録日2021-11-23
公開日2022-11-16
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
1W4J
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BU of 1w4j by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: PYRUVATE DEHYDROGENASE E2
著者Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
登録日2004-07-23
公開日2005-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family.
J. Mol. Biol., 353, 2005

 

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