8GCW
 
 | | Stx2A1(Y77A)-P6 peptide | | 分子名称: | P stalk protein, rRNA N-glycosylase | | 著者 | Rudolph, M.J, Li, X.P. | | 登録日 | 2023-03-03 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2.
Acs Infect Dis., 10, 2024
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8CX8
 | | Stx2A1-BTB13086 | | 分子名称: | 1,2-ETHANEDIOL, 5-(4-chlorophenyl)furan-2-carboxylic acid, CHLORIDE ION, ... | | 著者 | Rudolph, M.J, Li, X.P. | | 登録日 | 2022-05-20 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | | 主引用文献 | Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2.
Acs Infect Dis., 10, 2024
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8T9V
 | | RTA-RUNT-59 complex structure | | 分子名称: | (9aP)-7-fluoro-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, NONAETHYLENE GLYCOL, Ricin | | 著者 | Rudolph, M.J, Tumer, N. | | 登録日 | 2023-06-26 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.
Bioorg.Med.Chem., 100, 2024
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8TAB
 | | RTA-PD00589 | | 分子名称: | 1,2-ETHANEDIOL, 4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid, CHLORIDE ION, ... | | 著者 | Rudolph, M.J, Tumer, N. | | 登録日 | 2023-06-27 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.
Bioorg.Med.Chem., 100, 2024
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8TV3
 | | Fab 221-5 in complex with OspA | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Heavy chain of human monoclonal Fab 221-5, ... | | 著者 | Rudolph, M.J, Mantis, N. | | 登録日 | 2023-08-17 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | | 主引用文献 | Fab 221-5 in complex with OspA
To Be Published
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8TVD
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8TVJ
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8TUZ
 | | Fab 857-2 in complex with OspA | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Heavy chain of human monoclonal antibody 857-2, ... | | 著者 | Rudolph, M.J, Mantis, N. | | 登録日 | 2023-08-17 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.186 Å) | | 主引用文献 | Fab 857-2 in complex with OspA
To Be Published
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4Z9K
 | | Ricin A chain bound to camelid nanobody (VHH2)(F5) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2015-04-10 | | 公開日 | 2016-07-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
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2NYE
 | | Crystal structure of the Bateman2 domain of yeast Snf4 | | 分子名称: | Nuclear protein SNF4 | | 著者 | Rudolph, M.J, Amodeo, G.A, Iram, S, Hong, S, Pirino, G, Carlson, M, Tong, L. | | 登録日 | 2006-11-20 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
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2NYC
 | | Crystal structure of the Bateman2 domain of yeast Snf4 | | 分子名称: | Nuclear protein SNF4 | | 著者 | Rudolph, M.J, Amodeo, G.A, Iram, S, Hong, S, Pirino, G, Carlson, M, Tong, L. | | 登録日 | 2006-11-20 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
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8SZ2
 | | Stx2A1 bound to P8 stalk peptide | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, NONAETHYLENE GLYCOL, ... | | 著者 | rudolph, M.J, Li, X.P. | | 登録日 | 2023-05-26 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structure of Shiga toxin 2 A1 subunit with peptides that bind at the ribosome binding site and inhibit activity
To Be Published
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8TAD
 | | RTA in complex with inhibitor RUNT-206 | | 分子名称: | (9aM)-5,5-dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, CHLORIDE ION, NONAETHYLENE GLYCOL, ... | | 著者 | Rudolph, M.J, Tumer, N. | | 登録日 | 2023-06-27 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.
Bioorg.Med.Chem., 100, 2024
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6CWK
 | | Anti-RTA VHH antibody | | 分子名称: | 1,2-ETHANEDIOL, Anti-Ricin antibody, CHLORIDE ION, ... | | 著者 | Rudolph, M.J, Mantis, N. | | 登録日 | 2018-03-30 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.256 Å) | | 主引用文献 | Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
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6CWG
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5E1H
 | | Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs) | | 分子名称: | CHLORIDE ION, F8(JOB10) VHH antibody, Ricin | | 著者 | Rudolph, M.J, Vance, D, Shoemaker, C, Mantis, N. | | 登録日 | 2015-09-29 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | | 主引用文献 | Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
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5BOZ
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6OCD
 | | Ricin A chain bound to VHH antibody V6D4 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-22 | | 公開日 | 2020-04-01 | | 最終更新日 | 2020-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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6OBM
 | | Ricin A chain bound to VHH antibody V6A7 | | 分子名称: | CHLORIDE ION, Ricin A chain, VHH antibody V6A7 | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-21 | | 公開日 | 2020-04-01 | | 最終更新日 | 2020-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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3HYH
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6OBC
 | | Ricin A chain bound to camelid | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-20 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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6OBG
 | | Ricin A chain bound to VHH antibody V8E6 | | 分子名称: | CHLORIDE ION, Ricin A chain, VHH antibody V8E6, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-20 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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6OBE
 | | Ricin A chain bound to VHH antibody V6H8 | | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, NICKEL (II) ION, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-20 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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6OBO
 | | Ricin A chain bound to VHH antibody V6A6 | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-21 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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6OCA
 | | Ricin A chain bound to VHH antibody V2G10 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin A chain, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-22 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.113 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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