8RKS
 
 | | Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | | 著者 | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | | 登録日 | 2023-12-30 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21.
Protein Sci., 33, 2024
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1W3W
 | | The 2.1 Angstroem resolution structure of annexin A8 | | 分子名称: | ANNEXIN A8, CALCIUM ION | | 著者 | Rety, S, Sopkova-De Oliveira Santos, J, Renouard, M, Lewit-Bentley, A. | | 登録日 | 2004-07-20 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The Crystal Structure of Annexin A8 is Similar to that of Annexin A3
J.Mol.Biol., 345, 2005
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3ZDT
 | | Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A | | 分子名称: | FOCAL ADHESION KINASE 1 | | 著者 | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | | 登録日 | 2012-11-30 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5OSI
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL harpin loop (163-176) | | 分子名称: | 1,2-ETHANEDIOL, Interaptin, SODIUM ION, ... | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OSH
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236) | | 分子名称: | Interaptin, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OT4
 | | Structure of the Legionella pneumophila effector RidL (1-866) | | 分子名称: | GLYCEROL, Interaptin | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-20 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4CYE
 | | Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A | | 分子名称: | FOCAL ADHESION KINASE 1 | | 著者 | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | | 登録日 | 2014-04-10 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6GWS
 | | Crystal structure of human PCNA in complex with three p15 peptides | | 分子名称: | PCNA-associated factor, Proliferating cell nuclear antigen | | 著者 | De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-06-25 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
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6X6P
 | | Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Herrera, N.G, Morano, N.C, Celikgil, A, Georgiev, G.I, Malonis, R, Lee, J.H, Tong, K, Vergnolle, O, Massimi, A, Yen, L.Y, Noble, A.J, Kopylov, M, Bonanno, J.B, Garrett-Thompson, S.C, Hayes, D.B, Brenowitz, M, Garforth, S.J, Eng, E.T, Lai, J.R, Almo, S.C. | | 登録日 | 2020-05-28 | | 公開日 | 2020-06-10 | | 最終更新日 | 2021-01-27 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.
Biorxiv, 2020
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6HVO
 | | Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta | | 分子名称: | DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION | | 著者 | Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-10-11 | | 公開日 | 2019-01-23 | | 最終更新日 | 2019-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
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1BT6
 | | P11 (S100A10), LIGAND OF ANNEXIN II IN COMPLEX WITH ANNEXIN II N-TERMINUS | | 分子名称: | ANNEXIN II, S100A10 | | 著者 | Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A. | | 登録日 | 1998-09-02 | | 公開日 | 1999-01-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Nat.Struct.Biol., 6, 1999
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1A4P
 | | P11 (S100A10), LIGAND OF ANNEXIN II | | 分子名称: | S100A10 | | 著者 | Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Nat.Struct.Biol., 6, 1999
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1ANX
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1W45
 | | The 2.5 Angstroem structure of the K16A mutant of annexin A8, which has an intact N-terminus. | | 分子名称: | ANNEXIN A8 | | 著者 | Rety, S, Sopkova-de Oliveira Santos, J, Raguenes-Nicol, C, Dreyfuss, L, Blondeau, K, Hofbauerova, K, Renouard, M, Russo-Marie, F, Lewit-Bentley, A. | | 登録日 | 2004-07-22 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | The Crystal Structure of Annexin A8 is Similar to that of Annexin A3
J.Mol.Biol., 345, 2005
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3EJ1
 | | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor | | 分子名称: | Cell division protein kinase 2, Cyclin-A2, N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine | | 著者 | Stevens, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M. | | 登録日 | 2008-09-17 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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3EID
 | | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor | | 分子名称: | (2S)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol, Cell division protein kinase 2, Cyclin-A2 | | 著者 | Steven, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M. | | 登録日 | 2008-09-15 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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4UW8
 | | Structure of the carboxy-terminal domain of the bacteriophage T5 L- shaped tail fiber with its intra-molecular chaperone domain | | 分子名称: | CITRATE ANION, L-SHAPED TAIL FIBER PROTEIN | | 著者 | Garcia-Doval, C, Luque, D, Caston, J.R, Otero, J.M, Llamas-Saiz, A.L, Boulanger, P, van Raaij, M.J. | | 登録日 | 2014-08-08 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Structure of the Receptor-Binding Carboxy-Terminal Domain of the Bacteriophage T5 L-Shaped Tail Fibre with and without Its Intra-Molecular Chaperone.
Viruses, 7, 2015
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4UW7
 | | Structure of the carboxy-terminal domain of the bacteriophage T5 L- shaped tail fiber without its intra-molecular chaperone domain | | 分子名称: | GLYCEROL, L-SHAPED TAIL FIBER PROTEIN | | 著者 | Garcia-Doval, C, Luque, D, Caston, J.R, Otero, J.M, Llamas-Saiz, A.L, Boulanger, P, van Raaij, M.J. | | 登録日 | 2014-08-08 | | 公開日 | 2015-08-05 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Structure of the Receptor-Binding Carboxy-Terminal Domain of the Bacteriophage T5 L-Shaped Tail Fibre with and without Its Intra-Molecular Chaperone.
Viruses, 7, 2015
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6EHT
 | | Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme | | 分子名称: | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... | | 著者 | De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2017-09-15 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
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7Z1S
 | | X-ray crystal structure of SLPYL1-NIO complex | | 分子名称: | GLYCEROL, NICOTINIC ACID, SlPYL1-NIO | | 著者 | Infantes, L, Albert, A. | | 登録日 | 2022-02-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure-Based Modulation of the Ligand Sensitivity of a Tomato Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the Latch Loop.
Front Plant Sci, 13, 2022
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7Z1Q
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7Z1P
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7Z1R
 | | X-ray crystal structure of SLPYL1-E151D mutant ABA complex | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, GLYCEROL, SlPYL1-E151D ABA | | 著者 | Infantes, L, Albert, A. | | 登録日 | 2022-02-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Structure-Based Modulation of the Ligand Sensitivity of a Tomato Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the Latch Loop.
Front Plant Sci, 13, 2022
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6AX5
 | | RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1. | | 分子名称: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | | 著者 | Girvin, M.E, Cahill, S.M, Harris, R, Cowburn, D, Spira, M, Wu, X, Prakash, R, Bernowitz, M, Almo, S.C, Kalpana, G.V. | | 登録日 | 2017-09-06 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.
Nat Commun, 12, 2021
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4CZT
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