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2FO7
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BU of 2fo7 by Molmil
Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
分子名称: CADMIUM ION, SYNTHETIC CONSENSUS TPR PROTEIN
著者Kajander, T, Cortajarena, A.L, Regan, L.
登録日2006-01-12
公開日2006-03-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins.
Acta Crystallogr.,Sect.D, 63, 2007
2HYZ
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BU of 2hyz by Molmil
Crystal structure of an 8 repeat consensus TPR superhelix (orthorombic crystal form)
分子名称: SAMARIUM (III) ION, SYNTHETIC CONSENSUS TPR PROTEIN
著者Kajander, T, Cortajarena, A.L, Regan, L.
登録日2006-08-08
公開日2008-02-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins.
Acta Crystallogr.,Sect.D, 63, 2007
3KD7
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BU of 3kd7 by Molmil
Designed TPR module (CTPR390) in complex with its peptide-ligand (Hsp90 peptide)
分子名称: CTPR390, Hsp90 MEEVD peptide
著者Cortajarena, A.L, Wang, J, Regan, L.
登録日2009-10-22
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand.
Febs J., 277, 2010
1GTO
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BU of 1gto by Molmil
HIGH RESOLUTION STRUCTURE OF A HYPERSTABLE HELICAL BUNDLE PROTEIN MUTANT
分子名称: ROP
著者Agrawal, V, Predki, P, Regan, L, Brunger, A.T.
登録日1996-04-23
公開日1997-01-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Amino-acid substitutions in a surface turn modulate protein stability.
Nat.Struct.Biol., 3, 1996
1NA3
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BU of 1na3 by Molmil
Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
著者Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L.
登録日2002-11-26
公開日2003-06-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
1NA0
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BU of 1na0 by Molmil
Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, ACETATE ION, CHLORIDE ION, ...
著者Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L.
登録日2002-11-26
公開日2003-06-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
2AVP
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BU of 2avp by Molmil
Crystal structure of an 8 repeat consensus TPR superhelix
分子名称: CADMIUM ION, synthetic consensus TPR protein
著者Kajander, T, Cortajarena, A.L, Main, E.R, Mochrie, S, Regan, L.
登録日2005-08-30
公開日2005-09-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins.
Acta Crystallogr.,Sect.D, 63, 2007
2QND
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BU of 2qnd by Molmil
Crystal Structure of the KH1-KH2 domains from human Fragile X Mental Retardation Protein
分子名称: FMR1 protein, MAGNESIUM ION
著者Valverde, R, Regan, L.
登録日2007-07-18
公開日2007-11-06
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein.
Structure, 15, 2007
6CIU
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BU of 6ciu by Molmil
Structure of a Thr-rich interface in an Azami Green tetramer
分子名称: Azami-Green
著者Oi, C, Lim, C.S, Knecht, K.M, Xiong, Y, Regan, L.
登録日2018-02-25
公開日2018-09-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A threonine zipper that mediates protein-protein interactions: Structure and prediction.
Protein Sci., 27, 2018
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
分子名称: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
著者Kajander, T, Regan, L.
登録日2008-10-06
公開日2009-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
3FWV
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BU of 3fwv by Molmil
Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide
分子名称: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION
著者Jackrel, M.E, Valverde, R, Regan, L.
登録日2009-01-19
公開日2009-04-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
1F4M
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BU of 1f4m by Molmil
P3(2) CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
分子名称: CALCIUM ION, ROP ALA2ILE2-6
著者Willis, M.A, Bishop, B, Regan, L, Brunger, A.T.
登録日2000-06-08
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Structure Fold.Des., 8, 2000
1F4N
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BU of 1f4n by Molmil
C2 CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ROP ALA2ILE2-6
著者Willis, M.A, Bishop, B, Regan, L, Brunger, A.T.
登録日2000-06-08
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Structure Fold.Des., 8, 2000
1XNF
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BU of 1xnf by Molmil
Crystal structure of E.coli TPR-protein NlpI
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Lipoprotein nlpI
著者Wilson, C.G, Kajander, T, Regan, L.
登録日2004-10-04
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The crystal structure of NlpI. A prokaryotic tetratricopeptide repeat protein with a globular fold.
FEBS J., 272, 2005
6I2I
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BU of 6i2i by Molmil
Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Atherton, J.M, Moores, C.A.
登録日2018-11-01
公開日2019-08-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression.
Sci.Signal., 12, 2019
5DE2
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BU of 5de2 by Molmil
Structural mechanism of Nek7 activation by Nek9-induced dimerisation
分子名称: Serine/threonine-protein kinase Nek7, Serine/threonine-protein kinase Nek9
著者Haq, T, Bayliss, R.
登録日2015-08-25
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.
Nat Commun, 6, 2015
6FHK
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BU of 6fhk by Molmil
Structure of a modified protein containing a genetically encoded phosphoserine
分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A, MAGNESIUM ION, ...
著者Mukherjee, M, Bayliss, R.
登録日2018-01-14
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.657 Å)
主引用文献Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release.
Sci Signal, 11, 2018
2WQO
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BU of 2wqo by Molmil
STRUCTURE OF NEK2 BOUND TO THE AMINOPYRIDINE CCT241950
分子名称: 4-[2-AMINO-5-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-3-YL]BENZOIC ACID, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2
著者Mas-Droux, C, Bayliss, R.
登録日2009-08-24
公開日2009-12-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.167 Å)
主引用文献An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.
Mol.Cell, 36, 2009
2WQM
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BU of 2wqm by Molmil
Structure of apo human Nek7
分子名称: NICKEL (II) ION, SERINE/THREONINE-PROTEIN KINASE NEK7, SULFATE ION
著者Richards, M.W, Bayliss, R.
登録日2009-08-24
公開日2009-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Auto-Inhibitory Tyrosine Motif in the Cell-Cycle Regulated Nek7 Kinase is Released Through Binding of Nek9
Mol.Cell, 36, 2009
2WQN
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BU of 2wqn by Molmil
Structure of ADP-bound human Nek7
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICKEL (II) ION, ...
著者Richards, M.W, Bayliss, R.
登録日2009-08-24
公開日2009-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.
Mol.Cell, 36, 2009
4CGB
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BU of 4cgb by Molmil
Crystal structure of the trimerization domain of EML2
分子名称: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2, GLYCEROL, POTASSIUM ION
著者Richards, M.W, Bayliss, R.
登録日2013-11-21
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.154 Å)
主引用文献Microtubule Association of Eml Proteins and the Eml4-Alk Variant 3 Oncoprotein Require an N-Terminal Trimerization Domain.
Biochem.J., 467, 2015
4CI8
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BU of 4ci8 by Molmil
Crystal structure of the tandem atypical beta-propeller domain of EML1
分子名称: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1, SULFATE ION
著者Richards, M.W, Bayliss, R.
登録日2013-12-06
公開日2014-04-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Eml1 Reveals the Basis for Hsp90 Dependence of Oncogenic Eml4-Alk by Disruption of an Atypical Beta-Propeller Domain.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CGC
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BU of 4cgc by Molmil
Crystal structure of the trimerization domain of human EML4
分子名称: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4
著者Richards, M.W, Bayliss, R.
登録日2013-11-21
公開日2014-12-10
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Microtubule Association of Eml Proteins and the Eml4-Alk Variant 3 Oncoprotein Require an N-Terminal Trimerization Domain.
Biochem.J., 467, 2015
4NE1
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BU of 4ne1 by Molmil
Human MHF1 MHF2 DNA complexes
分子名称: Centromere protein S, Centromere protein X, DNA (26-MER)
著者Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y.
登録日2013-10-28
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (6.499 Å)
主引用文献The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
4NDY
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BU of 4ndy by Molmil
Human MHF1-MHF2 DNA complex
分子名称: Centromere protein S, Centromere protein X, DNA (26-MER)
著者Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y.
登録日2013-10-28
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (6.999 Å)
主引用文献The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014

 

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