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5UKW
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BU of 5ukw by Molmil
Crystal structure of human Glucose 6-phosphate Dehydrogenase mutant (A277C) complexed with G6P
分子名称: 6-O-phosphono-beta-D-glucopyranose, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase
著者Ranzani, A.T, Cordeiro, A.T.
登録日2017-01-23
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states.
FEBS Lett., 591, 2017
7MF4
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BU of 7mf4 by Molmil
Crystal structure of Trypanosoma cruzi cytosolic Malic Enzyme
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, Malic enzyme
著者Ranzani, A.T, Cordeiro, A.T.
登録日2021-04-08
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6CYR
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BU of 6cyr by Molmil
Crystal structure of the UBE2A variant Q93E
分子名称: Ubiquitin-conjugating enzyme E2 A
著者Ranzani, A.T, de Oliveira, J.F.
登録日2018-04-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat. Chem. Biol., 15, 2019
6CYO
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BU of 6cyo by Molmil
Crystal structure of human UBE2A (RAD6A)
分子名称: Ubiquitin-conjugating enzyme E2 A
著者Ranzani, A.T, de Oliveira, J.F.
登録日2018-04-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Nat. Chem. Biol., 15, 2019
6W29
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BU of 6w29 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC013)
分子名称: 3,5-bis(fluoranyl)-~{N}-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, ...
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-05
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W2N
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BU of 6w2n by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC009)
分子名称: 3,5-bis(fluoranyl)-~{N}-[3-[(2-fluoranyl-4-methoxy-phenyl)sulfamoyl]phenyl]benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, ...
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-06
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W59
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BU of 6w59 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC063)
分子名称: 3,5-bis(fluoranyl)-~{N}-[3-[[4-(trifluoromethyloxy)phenyl]sulfamoyl]phenyl]benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-12
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W49
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BU of 6w49 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC010)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, Malic enzyme, ...
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-10
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W57
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BU of 6w57 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC069)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme, ~{N}-[5-[[4-[bis(fluoranyl)methoxy]phenyl]sulfamoyl]-2-chloranyl-phenyl]-3,5-bis(fluoranyl)benzamide
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-12
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W53
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BU of 6w53 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC070)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme, N-(2-chloro-5-{[4-(trifluoromethoxy)phenyl]sulfamoyl}phenyl)-3,5-difluorobenzamide
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-12
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
6W56
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BU of 6w56 by Molmil
Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC062)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme, ~{N}-[3-[[4-[bis(fluoranyl)methoxy]phenyl]sulfamoyl]phenyl]-3,5-bis(fluoranyl)benzamide
著者Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T.
登録日2020-03-12
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box.
Acs Infect Dis., 7, 2021
7PGX
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BU of 7pgx by Molmil
Structure of dark-adapted AsLOV2 wild type
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.001 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
7PGZ
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BU of 7pgz by Molmil
Structure of dark-adapted AsLOV2 Q513L
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
7PH0
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BU of 7ph0 by Molmil
Structure of light-adapted AsLOV2 Q513L
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.979 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
7PGY
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BU of 7pgy by Molmil
Structure of light-adapted AsLOV2 wild type
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022

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件を2024-07-10に公開中

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