7MF4
Crystal structure of Trypanosoma cruzi cytosolic Malic Enzyme
Summary for 7MF4
Entry DOI | 10.2210/pdb7mf4/pdb |
Related | 6W29 6W2N 6W49 6W53 6W56 6W57 6W59 |
Descriptor | Malic enzyme, CITRIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | cytosol, oxidoreductase |
Biological source | Trypanosoma cruzi (strain CL Brener) |
Total number of polymer chains | 1 |
Total formula weight | 62040.84 |
Authors | Ranzani, A.T.,Cordeiro, A.T. (deposition date: 2021-04-08, release date: 2021-07-28, Last modification date: 2023-10-18) |
Primary citation | Mercaldi, G.F.,Eufrasio, A.G.,Ranzani, A.T.,do Nascimento Faria, J.,Mota, S.G.R.,Fagundes, M.,Bruder, M.,Cordeiro, A.T. Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box. Acs Infect Dis., 7:2455-2471, 2021 Cited by PubMed: 34279922DOI: 10.1021/acsinfecdis.1c00231 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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