2R9C
 
 | | Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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2R9F
 | | Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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3FOM
 | | Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL | | 分子名称: | 8 residue synthetic peptide, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | | 登録日 | 2008-12-30 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
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3FON
 | | Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI | | 分子名称: | Beta-2-microglobulin, MHC, Peptide | | 著者 | Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | | 登録日 | 2008-12-30 | | 公開日 | 2010-01-12 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
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3FOL
 | | Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFERI | | 分子名称: | 8 residue synthetic peptide, Beta-2-microglobulin, MHC | | 著者 | Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | | 登録日 | 2008-12-30 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect
Int.Immunol., 22, 2010
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1FC9
 | | PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE | | 分子名称: | PHOTOSYSTEM II D1 PROTEASE | | 著者 | Liao, D.I, Qian, J, Chisholm, D.A, Jordan, D.B, Diner, B.A. | | 登録日 | 2000-07-18 | | 公開日 | 2001-01-18 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of the photosystem II D1 C-terminal processing protease.
Nat.Struct.Biol., 7, 2000
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1FCF
 | | PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE | | 分子名称: | PHOTOSYSTEM II D1 PROTEASE, SULFATE ION | | 著者 | Liao, D.I, Qian, J, Chisholm, D.A, Jordan, D.B, Diner, B.A. | | 登録日 | 2000-07-18 | | 公開日 | 2001-01-18 | | 最終更新日 | 2018-10-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the photosystem II D1 C-terminal processing protease.
Nat.Struct.Biol., 7, 2000
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1FC6
 | | PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE | | 分子名称: | PHOTOSYSTEM II D1 PROTEASE | | 著者 | Liao, D.I, Qian, J, Chisholm, D.A, Jordan, D.B, Diner, B.A. | | 登録日 | 2000-07-18 | | 公開日 | 2001-01-18 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of the photosystem II D1 C-terminal processing protease.
Nat.Struct.Biol., 7, 2000
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1FC7
 | | PHOTOSYSTEM II D1 C-TERMINAL PROCESSING PROTEASE | | 分子名称: | PHOTOSYSTEM II D1 PROTEASE | | 著者 | Liao, D.I, Qian, J, Chisholm, D.A, Jordan, D.B, Diner, B.A. | | 登録日 | 2000-07-18 | | 公開日 | 2001-01-18 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the photosystem II D1 C-terminal processing protease.
Nat.Struct.Biol., 7, 2000
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8ZF1
 | | Crystal structure of a Chemo Triplet Photoenzyme (CTPe) | | 分子名称: | N-(9-oxidanylidenethioxanthen-2-yl)ethanamide, Transcriptional regulator, PadR-like family | | 著者 | Chen, X, Qian, J.Y, Guo, J, Wu, Y.Z, Zhong, F.R. | | 登録日 | 2024-05-07 | | 公開日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Chemogenetic Evolution of Diversified Photoenzymes for Enantioselective [2 + 2] Cycloadditions in Whole Cells.
J.Am.Chem.Soc., 2024
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6XSW
 | | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ... | | 著者 | Bard, J. | | 登録日 | 2020-07-16 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell Rep Med, 2, 2021
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4G9J
 | | Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide | | 著者 | Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J. | | 登録日 | 2012-07-24 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells.
Angew.Chem.Int.Ed.Engl., 51, 2012
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7XUP
 | | Crystal structure of TPe3.0 | | 分子名称: | Transcriptional regulator, PadR-like family | | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | | 登録日 | 2022-05-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes.
Nature, 611, 2022
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7XUQ
 | | Crystal structure of Tpe3.0 complexed with N-Boc-3-alkenylindole | | 分子名称: | Transcriptional regulator, PadR-like family, dimethyl 2-[[2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]methyl]-2-prop-2-enyl-propanedioate | | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | | 登録日 | 2022-05-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes.
Nature, 611, 2022
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3VK6
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7VW3
 | | Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex | | 分子名称: | CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ... | | 著者 | Du, W.H, Qian, J.Q, Huang, Q. | | 登録日 | 2021-11-09 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State.
Int J Mol Sci, 24, 2023
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5Z9R
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5C3U
 | | Crystal structure of a fungal L-serine ammonia-lyase from Rhizomucor miehei | | 分子名称: | L-serine ammonia-lyase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Zhen, Q, Qiaojuan, Y, Shaoqing, Y, Zhengqiang, J. | | 登録日 | 2015-06-17 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal structure and characterization of a novel l-serine ammonia-lyase from Rhizomucor miehei.
Biochem.Biophys.Res.Commun., 466, 2015
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