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1VOP
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CONSERVED RNA COMPONENT OF THE PEPTIDYL TRANSFERASE CENTER, NMR, 33 STRUCTURES
分子名称: 23S RIBOSOMAL RNA
著者Puglisi, E.V, Puglisi, J.D.
登録日1997-08-30
公開日1997-12-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a conserved RNA component of the peptidyl transferase centre.
Nat.Struct.Biol., 4, 1997
1BVJ
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BU of 1bvj by Molmil
HIV-1 RNA A-RICH HAIRPIN LOOP
分子名称: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3')
著者Puglisi, E.V, Puglisi, J.D.
登録日1998-08-31
公開日1998-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.
Nat.Struct.Biol., 5, 1998
6B19
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BU of 6b19 by Molmil
Architecture of HIV-1 reverse transcriptase initiation complex core
分子名称: RNA genome fragment, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit, ...
著者Larsen, K.P, Mathiharan, Y.K, Chen, D.H, Puglisi, J.D, Skiniotis, G, Puglisi, E.V.
登録日2017-09-18
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Architecture of an HIV-1 reverse transcriptase initiation complex.
Nature, 557, 2018
5BR8
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BU of 5br8 by Molmil
Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H.
登録日2015-05-29
公開日2015-11-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin
To Be Published
6WAZ
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BU of 6waz by Molmil
+1 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)
分子名称: HIV-1 viral RNA genome fragment, Reverse transcriptase p51 subunit, Reverse transcriptase/ribonuclease H, ...
著者Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V.
登録日2020-03-26
公開日2020-06-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WB0
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BU of 6wb0 by Molmil
+3 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)
分子名称: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ...
著者Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V.
登録日2020-03-26
公開日2020-06-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WB1
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+3 extended HIV-1 reverse transcriptase initiation complex core (intermediate state)
分子名称: HIV-1 viral RNA genome fragment, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, reverse transcriptase p51 subunit, ...
著者Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V.
登録日2020-03-26
公開日2020-06-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
6WB2
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BU of 6wb2 by Molmil
+3 extended HIV-1 reverse transcriptase initiation complex core (displaced state)
分子名称: HIV-1 viral RNA genome fragment, Reverse transcriptase/ribonuclease H, reverse transcriptase p51 subunit, ...
著者Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Chen, D.H, Puglisi, E.V.
登録日2020-03-26
公開日2020-06-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription.
J.Mol.Biol., 432, 2020
7KJX
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BU of 7kjx by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJV
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BU of 7kjv by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core
分子名称: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJW
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BU of 7kjw by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz
分子名称: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
著者Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
登録日2020-10-26
公開日2021-03-17
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7URI
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BU of 7uri by Molmil
allo-tRNAUTu1A in the A site of the E. coli ribosome
分子名称: Allo-tRNAUTu1A
著者Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
登録日2022-04-22
公開日2022-08-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7UR5
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allo-tRNAUTu1 in the A, P, and E sites of the E. coli ribosome
分子名称: allo-tRNAUTu1
著者Zhang, J, Krahn, N, Prabhakar, A, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
登録日2022-04-21
公開日2022-08-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
7URM
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BU of 7urm by Molmil
allo-tRNAUTu1A in the P site of the E. coli ribosome
分子名称: allo-tRNAUTU1A
著者Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J.
登録日2022-04-22
公開日2022-08-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Uncovering translation roadblocks during the development of a synthetic tRNA.
Nucleic Acids Res., 50, 2022
2M4Q
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BU of 2m4q by Molmil
NMR structure of E. coli ribosomela decoding site with apramycin
分子名称: APRAMYCIN, RNA (27-MER)
著者Puglisi, J.D, Tsai, A, Marshall, R, Viani, E.
登録日2013-02-10
公開日2013-03-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The impact of aminoglycosides on the dynamics of translation elongation.
Cell Rep, 3, 2013

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