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8FE3
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BU of 8fe3 by Molmil
Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody
分子名称: Envelope protein E, prM protein, prM12 Fab Heavy Chain, ...
著者Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
登録日2022-12-05
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (10.2 Å)
主引用文献prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FE4
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BU of 8fe4 by Molmil
Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody
分子名称: Envelope protein E, prM protein, prM13 Fab Heavy Chain, ...
著者Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
登録日2022-12-05
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
5IRE
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BU of 5ire by Molmil
The cryo-EM structure of Zika Virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein
著者Sirohi, D, Chen, Z, Sun, L, Klose, T, Pierson, T, Rossmann, M, Kuhn, R.
登録日2016-03-13
公開日2016-03-30
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The 3.8 angstrom resolution cryo-EM structure of Zika virus.
Science, 352, 2016
7KYL
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BU of 7kyl by Molmil
Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
分子名称: CHLORIDE ION, Envelope protein domain III, POWV-80 Fab heavy chain, ...
著者Errico, J.M, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-12-08
公開日2021-04-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
J.Exp.Med., 218, 2021
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
分子名称: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
著者Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-07-01
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
7T17
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BU of 7t17 by Molmil
Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment
分子名称: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ...
著者Miller, A.S, Kuhn, R.J.
登録日2021-12-01
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.26 Å)
主引用文献A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.
Cell, 185, 2022
5KVG
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BU of 5kvg by Molmil
Zika specific antibody, ZV-67, bound to ZIKA envelope DIII
分子名称: CHLORIDE ION, ZIKA Envelope DIII, ZV-67 Antibody Fab Heavy Chain, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2016-08-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVF
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BU of 5kvf by Molmil
Zika specific antibody, ZV-64, bound to ZIKA envelope DIII
分子名称: GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVE
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BU of 5kve by Molmil
Zika specific antibody, ZV-48, bound to ZIKA envelope DIII
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Genome polyprotein, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVD
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BU of 5kvd by Molmil
Zika specific antibody, ZV-2, bound to ZIKA envelope DIII
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ...
著者Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-07-14
公開日2016-08-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
4FFZ
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BU of 4ffz by Molmil
Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain).
分子名称: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E
著者Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-06-01
公開日2012-06-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
4FFY
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BU of 4ffy by Molmil
Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007.
分子名称: CHLORIDE ION, DENV1-E111 single chain variable fragment (heavy chain), DENV1-E111 single chain variable fragment (light chain), ...
著者Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-06-01
公開日2012-06-20
最終更新日2012-10-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
4L5F
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BU of 4l5f by Molmil
Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
分子名称: Envelope protein, Heavy chain of E106 antibody (VH and CH1 of IgG2c), Light chain of E106 antibody (kappa)
著者Edeling, M.A, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-06-11
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
To be Published
6CO8
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BU of 6co8 by Molmil
Structure of Zika virus at a resolution of 3.1 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein
著者Sevvana, M, Long, F, Miller, A.J, Klose, T, Buda, G, Sun, L, Kuhn, R.J, Rossmann, M.R.
登録日2018-03-12
公開日2018-07-04
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 angstrom Resolution.
Structure, 26, 2018

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件を2024-10-30に公開中

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