8T6B
 
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8T69
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8T6A
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6M0F
 | | X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in substrate-free form | | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment (9D5) Light chain, Antibody fragment (9D5) heavy chain, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-02-21 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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6M2R
 | | X-ray structure of a functional Drosophila dopamine transporter in L-norepinephrine bound form | | 分子名称: | Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, CHLORIDE ION, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-02-28 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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6M38
 | | X-ray structure of a Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in S-duloxetine bound form | | 分子名称: | (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, Antibody fragment 9D5 heavy chain, Antibody fragment 9D5 light chain, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-03-02 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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6M3Z
 | | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in milnacipran bound form | | 分子名称: | (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide, Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-03-04 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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6M0Z
 | | X-ray structure of Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in L-norepinephrine bound form | | 分子名称: | Antibody fragment (Fab) 9D5 Light chain, Antibody fragment (Fab) 9D5 heavy chain, CHLORIDE ION, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-02-24 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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6M47
 | | X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in tramadol bound form | | 分子名称: | (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol, Antibody fragment 9D5 light chain, Antibody fragment Heavy chain, ... | | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | | 登録日 | 2020-03-05 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.252 Å) | | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters.
Nat Commun, 12, 2021
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8GTS
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8GTR
 | | CryoEM structure of human Pannexin isoform 3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3 | | 著者 | Hussain, N, Penmatsa, A. | | 登録日 | 2022-09-08 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
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8GTT
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8XV5
 | | Pyridoxamine-bound human SLC19A3 | | 分子名称: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Soluble cytochrome b562,Thiamine transporter 2 | | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | | 登録日 | 2024-01-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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8XV2
 | | Thiamine-bound human SLC19A3 | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Soluble cytochrome b562,Thiamine transporter 2 | | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | | 登録日 | 2024-01-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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8XV9
 | | Fedratinib-bound human SLC19A3 | | 分子名称: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Soluble cytochrome b562,Thiamine transporter 2 | | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | | 登録日 | 2024-01-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3.
Cell Res., 34, 2024
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