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4LZ4
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BU of 4lz4 by Molmil
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ...
著者Pica, A, Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-07-31
公開日2014-01-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer.
Febs J., 280, 2013
4LZ1
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BU of 4lz1 by Molmil
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 12 nucleobase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ...
著者Pica, A, Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-07-31
公開日2014-01-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer.
Febs J., 280, 2013
5EW1
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BU of 5ew1 by Molmil
Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT3, ...
著者Pica, A, Russo Krauss, I, Parente, V, Sica, F.
登録日2015-11-20
公開日2016-11-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.
Nucleic Acids Res., 45, 2017
5EW2
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BU of 5ew2 by Molmil
Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT12, ...
著者Pica, A, Russo Krauss, I, Parente, V, Sica, F.
登録日2015-11-20
公開日2016-11-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.
Nucleic Acids Res., 45, 2017
4KXH
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BU of 4kxh by Molmil
The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease
分子名称: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ...
著者Pica, A, Merlino, A, Mazzarella, L, Sica, F.
登録日2013-05-26
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.
Acta Crystallogr.,Sect.D, 69, 2013
4Y23
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BU of 4y23 by Molmil
Crystal structure of T399A precursor mutant protein of gamma-glutamyl transpeptidase from Bacillus licheniformis
分子名称: Gamma glutamyl transpeptidase,Gamma-glutamyltranspeptidase, SODIUM ION
著者Pica, A, Merlino, A.
登録日2015-02-09
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The maturation mechanism of gamma-glutamyl transpeptidases: Insights from the crystal structure of a precursor mimic of the enzyme from Bacillus licheniformis and from site-directed mutagenesis studies.
Biochim.Biophys.Acta, 1864, 2015
5O7K
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BU of 5o7k by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 2.0
分子名称: Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
5O7L
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BU of 5o7l by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 4.6
分子名称: Monellin chain B, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
5O7S
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BU of 5o7s by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 8.3
分子名称: DI(HYDROXYETHYL)ETHER, Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
5O7R
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BU of 5o7r by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 6.5
分子名称: Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
5O7Q
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BU of 5o7q by Molmil
Crystal structure of a single chain monellin mutant (Y65R) pH 5.5
分子名称: DI(HYDROXYETHYL)ETHER, Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2017-06-09
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献pH driven fibrillar aggregation of the super-sweet protein Y65R-MNEI: A step-by-step structural analysis.
Biochim. Biophys. Acta, 1862, 2017
5LC7
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BU of 5lc7 by Molmil
Crystal structure of a single chain monellin mutant: E23Q/Q28K/C41S/Y65R-MNEI
分子名称: Monellin chain B,Monellin chain A
著者Pica, A, Merlino, A.
登録日2016-06-19
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Sweeter and stronger: enhancing sweetness and stability of the single chain monellin MNEI through molecular design.
Sci Rep, 6, 2016
5LC6
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BU of 5lc6 by Molmil
Crystal structure of a single chain monellin mutant: Q28K/C41S/Y65R-MNEI
分子名称: Monellin chain B,Monellin chain A, SULFATE ION
著者Pica, A, Merlino, A.
登録日2016-06-19
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Sweeter and stronger: enhancing sweetness and stability of the single chain monellin MNEI through molecular design.
Sci Rep, 6, 2016
6HJT
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BU of 6hjt by Molmil
The X-ray structure of the horse spleen ferritin nanocage containing Pt, obtained upon encapsulation of a Pt(II) terpyridine compound within the protein cage
分子名称: CADMIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Pica, A, Ferraro, G, Merlino, A.
登録日2018-09-04
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Preparation, structure, cytotoxicity and mechanism of action of ferritin-Pt(II) terpyridine compound nanocomposites.
Nanomedicine (Lond), 13, 2018
6HJU
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BU of 6hju by Molmil
The X-ray structure of the horse spleen ferritin nanocage containing Pt, obtained upon encapsulation of a Pt(II) terpyridine compound within the protein cage
分子名称: CADMIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Pica, A, Ferraro, G, Merlino, A.
登録日2018-09-04
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Preparation, structure, cytotoxicity and mechanism of action of ferritin-Pt(II) terpyridine compound nanocomposites.
Nanomedicine (Lond), 13, 2018
6GXJ
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BU of 6gxj by Molmil
X-ray structure of DiRu-1-encapsulated Apoferritin
分子名称: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
著者Pica, A, Ferraro, G, Merlino, A.
登録日2018-06-27
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Encapsulation of the Dinuclear Trithiolato-Bridged Arene Ruthenium Complex Diruthenium-1 in an Apoferritin Nanocage: Structure and Cytotoxicity.
ChemMedChem, 14, 2019
4I7Y
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BU of 4i7y by Molmil
Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ...
著者Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F.
登録日2012-12-01
公開日2013-10-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer.
Acta Crystallogr.,Sect.D, 69, 2013
4N4C
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BU of 4n4c by Molmil
Crystal structure of the C-terminal swapped dimer of a Bovine seminal ribonuclease mutant
分子名称: PHOSPHATE ION, Seminal ribonuclease
著者Pica, A, Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-10-08
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer.
Febs Lett., 587, 2013
6ZJF
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BU of 6zjf by Molmil
Crystal structure of STK17B (DRAK2) in complex with AP-229
分子名称: 1,2-ETHANEDIOL, 2-[6-(4-cyclopropylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic acid, Serine/threonine-protein kinase 17B
著者Chaikuad, A, Picado, A, Willson, T, Knapp, S, Structural Genomics Consortium (SGC)
登録日2020-06-28
公開日2020-07-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
J.Med.Chem., 63, 2020
4G51
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BU of 4g51 by Molmil
Crystallographic analysis of the interaction of nitric oxide with hemoglobin from Trematomus bernacchii in the T quaternary structure (fully ligated state).
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, NITRIC OXIDE, ...
著者Merlino, A, Balsamo, A, Pica, A, Mazzarella, L, Vergara, A.
登録日2012-07-17
公開日2013-01-16
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study.
Acta Crystallogr.,Sect.D, 69, 2013
4YIP
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BU of 4yip by Molmil
X-ray structure of the iron/manganese cambialistic superoxide dismutase from Streptococcus mutans
分子名称: FE (III) ION, Superoxide dismutase [Mn/Fe]
著者Russo Krauss, I, Merlino, A, Pica, A, Sica, F.
登録日2015-03-02
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases
Rsc Adv, 5, 2015
4YIO
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BU of 4yio by Molmil
X-ray structure of the iron/manganese cambialistic superoxide dismutase from Streptococcus thermophilus
分子名称: FE (III) ION, GLYCEROL, SULFATE ION, ...
著者Russo Krauss, I, Merlino, A, Pica, A, Sica, F.
登録日2015-03-02
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases
Rsc Adv, 5, 2015
5FCP
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BU of 5fcp by Molmil
X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN AT LONG INCUBATION TIMES
分子名称: CHLORIDE ION, Cisplatin, GLYCEROL, ...
著者Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A.
登録日2015-12-15
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme.
J.Biol.Inorg.Chem., 21, 2016
5F9X
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BU of 5f9x by Molmil
X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 55 DEGREES
分子名称: Cisplatin, GLYCEROL, Lysozyme C
著者Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A.
登録日2015-12-10
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme.
J.Biol.Inorg.Chem., 21, 2016
5F9U
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BU of 5f9u by Molmil
X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 20 DEGREES
分子名称: Cisplatin, GLYCEROL, Lysozyme C
著者Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A.
登録日2015-12-10
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme.
J.Biol.Inorg.Chem., 21, 2016

 

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